Abstract: The present disclosure relates to a positive pressure breathing circuit and a method for ventilating a patient. The breathing circuit can be used in any type of pressurized breathing therapy including, for example, continuous positive air (way) pressure (CPAP) therapy and bilevel positive air pressure therapy where the inspiratory and expiratory pressures differ.

Abstract: Heat sink devices which gradually increase the effective heat transfer coefficient (HTC) of a cooling fluid flowing along a row of power electronics devices are described. The heat sink devices may allow substantially uniform cooling of the plurality of power electronics devices, regardless of the temperature of the cooling fluid when it contacts them. The heat sink devices allow the HTC to be increased as needed down the row of power electronics devices resulting in power electronics devices cooled to substantially the same temperatures. The heat sink devices may include fins.

Abstract: Various embodiments of the present technology generally relate to systems and methods for providing an analytics service governance system to provide data visualizations of system-level metadata. In certain embodiments, a method may comprise operating a data analytics system to implement an analytics service governance process to generate data visualizations (DVs) of system-level metadata using an analytics service configured to generate DVs of user-provided datasets.

Abstract: A method of manufacturing a ceramic honeycomb structure by mixing a ceramic precursor batch composition having a median particle diameter less than or equal to about 10 ?m and at least one starch-based pore former having a median particle diameter greater than or equal to about 10 ?m. The method also includes forming a mixture of ceramic precursor batch composition and a starch-based pore former into a green ceramic structure having a web structure, and firing the green ceramic structure to yield a ceramic honeycomb structure.

Abstract: The invention relates to methods of monitoring treatment response, disease resolution, and disease progression in subjects having inflammatory bowel disease (IBD).

Abstract: The invention relates to methods of predicting a patient's responsiveness to treatment (e.g., vedolizumab treatment) for inflammatory bowel disease (IBD).

Abstract: Methods for filling gaps with dielectric material involve deposition using an atomic layer deposition (ALD) technique to fill a gap followed by deposition of a cap layer on the filled gap by a chemical vapor deposition (CVD) technique. The ALD deposition may be a plasma-enhanced ALD (PEALD) or thermal ALD (tALD) deposition. The CVD deposition may be plasma-enhanced CVD (PECVD) or thermal CVD (tCVD) deposition. In some embodiments, the CVD deposition is performed in the same chamber as the ALD deposition without intervening process operations. This in-situ deposition of the cap layer results in a high throughput process with high uniformity. After the process, the wafer is ready for chemical-mechanical planarization (CMP) in some embodiments.

Abstract: Apparatuses, systems, and techniques for performing color correction are presented. In at least one embodiment, a color mapping model may be identified that maps colors, within a subspace of an input color space localized around a target color, to an adjusted color space and applied to an input image to adjust a value of one or more pixels of the input image that fall within the subspace. In at least one embodiment, a color mapping model may be initialized that maps colors, within a subspace of an input color space localized around a target color, to an adjusted color space. At least one parameter of the color mapping model may be adjusted to reduce an amount of visible artifacts produced by the color mapping model.

Abstract: Embodiments disclosed herein include playback devices configured to operate in one or more playback configurations including configurations individual playback devices play back one or more corresponding channels of multichannel audio content. An audio parameter can be determined based on a distance between playback devices. In some examples, the audio parameter comprises a filter such as a low frequency filter that varies based on at least the distance between the playback devices. After the audio parameter is determined, the playback devices can play back audio content according to the determined audio parameter.

Abstract: Provided herein are methods of treating cancer, an infectious disease, or an infection, which comprise administering to a human patient in need thereof: (a) a TIGIT antagonist; (b) a PD-1 antagonist; and (c) lenvatinib represented by Formula (I), or a pharmaceutically acceptable salt thereof. Also provided are kits containing such agents and uses of therapeutic combinations of such agents for the treatment of cancer, an infectious disease, or an infection.

Abstract: Embodiments disclosed herein include playback devices configured to operate in one or more playback configurations including configurations individual playback devices play back one or more corresponding channels of multichannel audio content. An audio parameter can be determined based on a distance between playback devices. In some examples, the audio parameter comprises a filter such as a low frequency filter that varies based on at least the distance between the playback devices. After the audio parameter is determined, the playback devices can play back audio content according to the determined audio parameter.

Abstract: Compositions comprising donor cells, acceptor cells, and methods involving the same are described herein. In some embodiments, the donor cell is deficient in at least one endogenous function, for instance cytotoxic activity. In some embodiments, the donor cell comprises a T cell receptor (TCR) and a cargo, and the acceptor cell comprises an MHC. In some embodiments, the TCR facilitates transfer of the cargo to the acceptor cell. In some embodiments, the donor cell comprises a chimeric antigen receptor (CAR) and a cargo, and the acceptor cell comprises an antigen bound by the CAR. In some embodiments, the CAR facilitates transfer of the cargo to the acceptor cell.

Abstract: A glass manufacturing apparatus includes a forming apparatus defining a travel path extending in a travel direction. The forming apparatus conveys a ribbon of glass-forming material along the travel path in the travel direction of the forming apparatus. The glass manufacturing apparatus includes a cooling tube extending substantially parallel to the travel path and extending across the travel direction. The cooling tube includes a plurality of orifices spaced apart along the cooling tube and facing the travel path. Methods of manufacturing glass can comprise flowing a coolant from an outlet of a conduit in a direction toward a target location of a flowing ribbon of molten material. Methods can also include changing a phase of the coolant while the coolant is flowing towards the target location. The change in phase can cool the target location.

Abstract: A multi-point sliding door lock includes a lock assembly and a cartridge assembly, the lock assembly is configured to receive the cartridge assembly in a plurality of different positions spaced along a longitudinal axis. The lock assembly includes a lock housing supporting a pair of latch elements configured to move between an extended position and a retracted position. A slide plate is disposed within the lock housing and engaged with the pair of latch elements such that sliding movement of the slide plate pivots each of the pair of latch elements. The cartridge assembly includes a cartridge housing insertable at least partially into the lock housing. A hub is rotatably mounted at least partially within the cartridge housing. The hub engages with the slide plate when the cartridge assembly is received by the lock assembly such that rotation of the hub drives the sliding movement of the slide plate.

Abstract: A particulate filter having a honeycomb structure of a matrix of interconnected porous walls including inlet cells and outlet cells defining a plurality of inlet channels and outlet channels, respectively, wherein at least a portion of the outlet cells are larger than any of the inlet cells, and a cross-sectional shape of at least some of the outlet channels is rectangular. Honeycomb extrusion dies, honeycomb bodies, honeycomb structures, and methods of manufacture are described, as are other aspects.

Abstract: The invention relates to a breathing assistance apparatus that may be configured to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks within the apparatus or impacts to the apparatus. In other forms, the apparatus may be configured to allow for easy assembly and/or safe operation.

Abstract: A data intake and query system can manage the search of data stored at an external location relative to the data intake and query system using one or more indexers. The data intake and query system can receive data stored at the external location. The data intake and query system can process the data and generate an index using the one or more indexers. The data intake and query system can discard the data and store the index and a location identifier of the external location in one or more buckets. In response to a query, the data intake and query system can identify that at least a subset of the data is responsive to the query using the index and can obtain the at least the subset of the data from the external location using the location identifier.

Abstract: One example of an IP KVM device includes a USB port, a display port, a communication port, a network port, and a processor communicatively coupled to the USB port, display port, communication port, and network port. The USB port may be communicatively coupled to a host device to receive first USB signals from the host device. The display port may be communicatively coupled to the host device to receive first display signals from the host device. The communication port may be communicatively coupled to a secondary IP KVM device to receive second USB signals from the host device and second display signals from the host device. The network port may be communicatively coupled to a network. The processor is to aggregate the first and second USB signals and the first and second display signals and output the aggregated USB signals and display signals via the network port.

Abstract: A vehicle battery terminal clamp assembly features a clasping mechanism and a securement assembly. The clasping mechanism includes a top wall with an upper battery post aperture and an upper slit, a bottom wall with a lower battery post aperture and a lower slit, and a front wall integrally extending between the top and bottom walls and including a front slit, and wherein the upper slit, the lower slit, and the front slit are arranged to form a continuous slit that extends from the upper battery post aperture, across the front wall and to the lower battery post aperture. The upper and lower battery post apertures are configured to receive an extent of a post extending from the vehicle battery. The securement assembly applies less than a nominal compressive force on the clasping mechanism, wherein the top wall of the clasping mechanism is substantially parallel with the bottom wall of the clasping mechanism.

Abstract: A CVD single crystal diamond having a smallest linear dimension of no less than 3.5 mm, a concentration of single substitutional nitrogen atoms in their neutral charge state (Ns0), as measured by EPR, of between 20 and 250 ppb, a hue angle, hab, between 75 and 135°.