Abstract: A system for generating a target image comprises an endoscope having an image collection component, a computing device communicatively connected to the image collection component of the endoscope, comprising a non-transitory computer-readable medium with instructions stored thereon, which when executed by a processor perform steps comprising receiving at least one input image from the image collection component of the endoscope, providing the at least one input image as an input to a machine learning algorithm, generating a target image from the at least one input image using the machine learning algorithm, and providing the at least one input image and the target image to a display driver, and a display device, communicatively connected to the computing device, and configured to display the images provided to the display driver. A method of training a machine learning algorithm and a method of generating a stereoscopic image are also disclosed.

Abstract: Methods, systems, and apparatuses are disclosed for radiation treatment of tumors based at least in part on patient-specific imaging information. The methods, systems and apparatuses include computer programs encoded on computer-readable media. The methods include acquiring imaging information relating to a target to be treated. The imaging information is non-anatomic imaging information relating to the target acquired from at least one imaging marker that reflects at least one of the metabolic, physiological and histological features of the target. The methods further include computing a radiation dose based at least on the imaging information.

Abstract: Methods, systems, and apparatuses are disclosed for radiation treatment of tumors based at least in part on patient-specific imaging information. The methods, systems and apparatuses include computer programs encoded on computer-readable media. The methods include acquiring imaging information relating to a target to be treated. The imaging information is non-anatomic imaging information relating to the target acquired from at least one imaging marker that reflects at least one of the metabolic, physiological and histological features of the target. The methods further include computing a radiation dose based at least on the imaging information.

Abstract: Methods, systems, and apparatuses are disclosed for radiation treatment of tumors based at least in part on patient-specific imaging information. The methods, systems and apparatuses include computer programs encoded on computer-readable media. The methods include acquiring imaging information relating to a target to be treated. The imaging information is non-anatomic imaging information relating to the target acquired from at least one imaging marker that reflects at least one of the metabolic, physiological and histological features of the target. The methods further include computing a radiation dose based at least on the imaging information.

Abstract: A method of treating stroke in a patient who has undergone a stroke comprising administering at least 2 million suitable neuronal cells in at least one brain area involved in the stroke. The method comprises the step of using a twist drill or a burr to form a hole in the skull through which the cells could be administered. Exemplary cells are hNT neuronal cells, HCN-1 cells, fetal pig cells, neural crest cells, neural stem cells, or a combination thereof. Also disclosed herein is a pharmaceutical composition of 95% pure hNT neuronal cells, which composition further includes a vial containing PBS and human neuronal cells. This vial is provided in a container with liquid nitrogen, whereby the composition is frozen and maintained at ?170° C. before use.

Abstract: Apparatuses and methods for the effective implantation of viable cells into the body of a patient. Apparatuses and methods are disclosed that are particularly useful for the effective implantation of viable cells into a patient. The apparatuses preferably include a syringe with a small or zero dead volume, a cannula adapted for cell implantation, and a rotational chamber. The syringe is able to hold a cellular suspension for administration to a patient. The apparatuses and methods also preferably employ a small motor which is adapted to rotate the syringe, cannula, and rotational chamber slowly. That rotation reduces cell clumping in the cellular suspension and better maintains the cellular suspension during the implantation procedure. The apparatuses and methods are particularly well suited for the implantation of neurons into the brain of a patient. The apparatuses and methods may also be used to control the rate and volume of cell delivery during implantation precisely and in an automated manner.

Abstract: A method of treating stroke in a patient who has undergone a stroke comprising administering at least 2 million suitable neuronal cells to at least one brain area involved in the stroke. The method comprises the step of using a twist drill or a burr to form a hole in the skull through which the cells could be administered. Exemplary cells are hNT neuronal cells, HCN-1 cells, fetal pig cells, neural crest cells, neural stem cells, or a combination thereof. Also disclosed herein is a pharmaceutical composition of 95% pure hNT neuronal cells, which composition further includes a vial containing PBS and human neuronal cells. This vial is provided in a container with liquid nitrogen, whereby the composition is frozen and maintained at −170° C. before use.