Patents by Inventor Douglas L. Tolson

Douglas L. Tolson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Archaeosomes, archaeosomes containing coenzyme Q.sub.10, and other types of liposomes containing coenzyme Q.sub.10 as adjuvants and as delivery vehicles
    Patent number: 6132789
    Abstract: Novel archaeosome compositions and their use in vaccine formulations as adjuvants and/or delivery systems, to enhance the immune response to immunogens in an animal such as a human, are described. Another aspect relates to the use of these archaeosomes to enhance the delivery of compounds such as pharmaceuticals to specific cell types and tissues in animals and other life forms, via various routes of administration such as subcutaneous, intramuscular, and oral. The efficacy of the archaeosomes and also of conventional liposomes can be further improved in these applications by incorporation of coenzyme Q.sub.10 and/or polyethyleneglycol-lipid conjugate into liposomes made from these archaeosomes.
    Type: Grant
    Filed: June 12, 1998
    Date of Patent: October 17, 2000
    Assignee: National Research Council of Canada
    Inventors: G. Dennis Sprott, Girishchandra B. Patel, Boby Makabi-Panzu, Douglas L. Tolson