Abstract: Described herein are compounds that inhibit ALK2 and its mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

Abstract: A fiber management device includes a support member including a first connector for releasably securing a first sidewall portion of an optical fiber bundle to the support member at a first fixed location and a drawer mounted for sliding movement relative to the support member, the drawer including a mounting surface, a plurality of fiber guiding components mounted on the mounting surface, and a second connector for releasably securing a second sidewall portion of the optical fiber bundle to the drawer at a second fixed location.

Abstract: It has been demonstrated that B containing glasses are sensitive to radiation in the band 225-275 nm and, therefore, B2O3 glasses are particularly adapted to receive refractive index modulation, e.g., to make reflection gratings. Glasses containing SiO2 and B2O3 are particularly suitable when the grating is to be localized in the cladding of a fiber. Glasses containing SiO2, GeO2, and B2O3 are suitable when the grating is in the path region of a waveguide, e.g., in the core of a fiber.

Abstract: An optical device includes a waveguiding configuration and an electrical capacitive configuration. The capacitive configuration includes glass electrode region(s) and glass dielectric region(s) with electrical leads, e.g., metallic conductors, for applying electrical control signals to the electrode region(s). The preferred metals for the conductors are Ni, Ti and Au. The waveguiding structure is configured so that the fields associated with optical signals propagating therein interact with dielectric region(s). During the use of the device control signals are applied to the dielectric region(s) by the electrical leads. The control signals have the effect that temporary electric fields are applied to the dielectric region(s). The fields change the optical properties of the dielectric region(s) and this affects the propagation of the optical signals. The device can either be produced in planar or fibre configurations.

Abstract: Boron containing glasses are sensitive to radiation in the band 225-275 nm and therefore, B.sub.2 O.sub.3 glasses are particularly adapted to receive refractive index modulation, e.g., to make reflection gratings. Glasses containing SiO.sub.2 and B.sub.2 O.sub.3 are particularly suitable when the grating is to be localized in the cladding of a fibre. Glasses containing SiO.sub.2, GeO.sub.2 and B.sub.2 O.sub.3 are suitable when the grating is in the path region of a waveguide, e.g., in the core of a fibre.

Abstract: It has been demonstrated that B containing glasses are sensitive to radiation in the band 225-275 nm and, therefore, B.sub.2 O.sub.3 glasses are particularly adapted to receive refractive index modulation, e.g., to make reflection gratings. Glasses containing SiO.sub.2 and B.sub.2 O.sub.3 are particularly suitable when the grating is to be localized in the cladding of a fiber. Glasses containing SiO.sub.2, GeO.sub.2, and B.sub.2 O.sub.3 are suitable when the grating is in the path region of a waveguide, e.g., in the core of a fiber.