Patents by Inventor Douglas Lake

Douglas Lake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QSOX1 as an anti-neoplastic drug target
    Patent number: 8946186
    Abstract: The present invention provides methods for tumor treatment by administering an inhibitor of quiescin sulfhydryl oxidase 1 (QSOX1), compositions comprising such inhibitors, and methods for identifying such inhibitors.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: February 3, 2015
    Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
    Inventors: Douglas Lake, Benjamin Katchman
  • Methods of detection of species in bodily fluid
    Patent number: 8911959
    Abstract: Coccidioidomycosis (Valley Fever) is currently diagnosed by relying on infected individuals (humans, dogs, etc.) to generate antibodies against the fungus. Since the immune response against Valley Fever can be delayed or absent in many cases, methods that detect a polypeptide or peptide component of the Coccidioides sp. fungus in a bodily fluid such as blood are provided.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: December 16, 2014
    Assignees: Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizona State University, Mayo Foundation for Medical Education and Research
    Inventors: Douglas Lake, Kwasi Antwi, Janis E. Blair
  • QSOX1 as an Anti-Neoplastic Drug Target
    Publication number: 20140141015
    Abstract: The present invention provides methods for tumor treatment by administering an inhibitor of quiescin sulfhydryl oxidase 1 (QSOX1), compositions comprising such inhibitors, and methods for identifying such inhibitors.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 22, 2014
    Inventors: Douglas Lake, Benjamin Katchman
  • QSOX1 as an Anti-Neoplastic Drug Target
    Publication number: 20130287793
    Abstract: The present invention provides methods for tumor treatment by administering an inhibitor of quiescin sulfhydryl oxidase 1 (QSOX1), compositions comprising such inhibitors, and methods for identifying such inhibitors.
    Type: Application
    Filed: March 20, 2013
    Publication date: October 31, 2013
    Inventors: Douglas Lake, Benjamin Katchman
  • Methods of Detection of Coccidioides Species in Bodily Fluid
    Publication number: 20130164764
    Abstract: Coccidioidomycosis (Valley Fever) is currently diagnosed by relying on infected individuals (humans, dogs, etc.) to generate antibodies against the fungus. Since the immune response against Valley Fever can be delayed or absent in many cases, methods that detect a polypeptide or peptide component of the Coccidioides sp. fungus in a bodily fluid such as blood are provided.
    Type: Application
    Filed: September 10, 2012
    Publication date: June 27, 2013
    Inventors: Douglas Lake, Kwasi Antwi, Janis E. Blair
  • Monoclonal antibodies specific for HIV and the hybridomas for production thereof
    Patent number: 5783670
    Abstract: Human monoclonal antibodies which belong to the IgGl subclass and are specific for HIV are described. The monoclonal antibodies have potential for use in the diagnosis, prevention and therapy of HIV infection.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 21, 1998
    Assignees: The University of Arizona, Department of Internal Medicine, Section of Hematology and Oncology, Teijin Limited
    Inventors: Yasuhiko Masuho, Toru Sugano, Yoh-ichi Matsumoto, Takashi Kawamura, Evan Hersh, Eskild Petersen, Douglas Lake
  • Monoclonal antibodies specific for HIV and the hybridomas for production thereof
    Patent number: 5695927
    Abstract: Human monoclonal antibodies which belong to the IgG1 subclass and are specific for HIV are described. The monoclonal antibodies have potential for use in the diagnosis, prevention and therapy of HIV infection.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: December 9, 1997
    Assignees: The University of Arizona, Department of Internal Medicine, Section of Hematology and Oncology, Teijin Limited
    Inventors: Yasuhiko Masuho, Toru Sugano, Yoh-ichi Matsumoto, Takashi Kawamura, Evan Hersh, Eskild Petersen, Douglas Lake
  • Monoclonal antibodies specific for HIV and hybridomas for their production
    Patent number: 5445960
    Abstract: Human IgG1 monoclonal antibodies are produced by hybridoma ATCC HB10074 and bind to gp120 of HIV.
    Type: Grant
    Filed: May 24, 1993
    Date of Patent: August 29, 1995
    Assignees: The Arizona Board of Regents on behalf of the University of Arizona, Teijin Limited
    Inventors: Yasuhiko Masuho, Toru Sugano, Yoh-Ichi Matsumoto, Evan M. Hersh, Eskild A. Petersen, Douglas Lake, Takashi Kawamura
  • Adjustable, fluid-filled breast implant
    Patent number: 4095295
    Abstract: An improved fluid-filled breast prosthesis for implantation which permits subsequent alterations in the fluid volume of the implant without the necessity for major surgery. The prosthesis comprises a flexible plastic bag having an elongated filler tube including a loop near its outer end. After the prosthesis has been interposed into the surgically prepared implant site, the filler tube is drawn out through a small stab wound connected to the site which terminates adjacent the arm pit. After the plastic bag is filled with fluid, the filler tube is plugged and clamped, and the loop is sutured to the tissue to hold the implant in place. The radiopaque nature of the plug and clamp, and a connected filament, enable the end of the tube to be readily located and grasped subsequent to the operation, using a simple office procedure to adjust the volume of fluid in the bag.
    Type: Grant
    Filed: March 28, 1977
    Date of Patent: June 20, 1978
    Inventor: Douglas Lake