Patents by Inventor Douglas Lee Pittman

Douglas Lee Pittman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for affecting homology-directed DNA double stranded break repair
    Patent number: 9095561
    Abstract: Disclosed herein are methods and composition for alteration of the presence, activity, or concentration of RNF138. Disclosed methods can be utilized to affect DNA double strand break repair. Methods and compositions can be utilized to alter RNF138 so as to prevent interaction between RNF138 and RAD51D. Specifically, methods can prevent RNF138-directed ubiquitylation of RAD51D, which is necessary for DNA double strand break repair.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: August 4, 2015
    Assignee: University of South Carolina
    Inventors: Douglas Lee Pittman, Brian David Yard
  • Methods for Affecting Homology-Directed DNA Double Stranded Break Repair
    Publication number: 20140010893
    Abstract: Disclosed herein are methods and composition for alteration of the presence, activity, or concentration of RNF138. Disclosed methods can be utilized to affect DNA double strand break repair. Methods and compositions can be utilized to alter RNF138 so as to prevent interaction between RNF138 and RAD51D. Specifically, methods can prevent RNF138-directed ubiquitylation of RAD51D, which is necessary for DNA double strand break repair.
    Type: Application
    Filed: September 17, 2013
    Publication date: January 9, 2014
    Applicant: University of South Carolina
    Inventors: Douglas Lee Pittman, Brian David Yard