Patents by Inventor Douglas McCann

Douglas McCann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ELECTROPHORETIC TAG-BASED IN VITRO ASSAY TO QUANTIFY DIMERIZATION OF P66 AND P51 SUB-UNITS OF HIV-1 REVERSE TRANSCRIPTASE (RT)
    Publication number: 20120003667
    Abstract: Methods for measuring hetero- and homodimerization of HIV reverse transcriptase (HIV RT) are provided using pairs of tagged probes and cleaving probes. The methods can be used, for example, to screen for modulators of HIV RT dimerization. Also provided are methods of determining whether a compound modulates HIV RT. Further provided are methods of determining whether a compound modulates formation of a complex between a p66 and p51, p66 and p66, or p51 and p55 subunits polypeptides of HIV RT.
    Type: Application
    Filed: June 16, 2008
    Publication date: January 5, 2012
    Inventors: Soumi Gupta, Rajiv Dua, Douglas McCann