Patents by Inventor Douglas Ohlendorf

Douglas Ohlendorf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutants of streptococcal toxin a and methods of use
    Publication number: 20060039925
    Abstract: This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
    Type: Application
    Filed: March 21, 2005
    Publication date: February 23, 2006
    Applicant: Regents of the University of Minnesota
    Inventors: Patrick Schlievert, Manuela Roggiani, Jennifer Stoehr, Douglas Ohlendorf
  • Mutants of streptococcal toxin A and methods of use
    Publication number: 20060041107
    Abstract: This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
    Type: Application
    Filed: July 5, 2005
    Publication date: February 23, 2006
    Applicant: Regents of the University of Minnesota
    Inventors: Patrick Schlievert, Manuela Roggiani, Jennifer Auge, Douglas Ohlendorf
  • Mutants of Streptococcal toxin A and methods of use
    Patent number: 6913755
    Abstract: This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
    Type: Grant
    Filed: December 5, 1997
    Date of Patent: July 5, 2005
    Assignee: Regents of the University of Minnesota
    Inventors: Patrick M. Schlievert, Manuela Roggiani, Jennifer Stoehr Stoehr, Douglas Ohlendorf
  • Mutants of streptococcal toxin A and methods of use
    Patent number: 6870042
    Abstract: This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: March 22, 2005
    Assignee: Regents of the University of Minnesota
    Inventors: Patrick M. Schlievert, Manuela Roggiani, Jennifer Stoehr, Douglas Ohlendorf
  • Mutants of streptococcal toxin C and methods of use
    Publication number: 20050010034
    Abstract: This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-C toxin. The mutant SPE-C toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-C toxin.
    Type: Application
    Filed: August 9, 2004
    Publication date: January 13, 2005
    Applicant: Regents of the University of Minnesota
    Inventors: Patrick Schlievert, Douglas Ohlendorf, David Mitchell, Pamala Gahr
  • Mutants of streptococcal toxin C and methods of use
    Publication number: 20050010033
    Abstract: This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-C toxin. The mutant SPE-C toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-C toxin.
    Type: Application
    Filed: August 9, 2004
    Publication date: January 13, 2005
    Applicant: Regents of the University of Minnesota
    Inventors: Patrick Schlievert, Douglas Ohlendorf, David Mitchell, Pamala Gahr
  • Mutants of Streptococcal toxin C and methods of use
    Patent number: 6835818
    Abstract: This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-C toxin. The mutant SPE-C toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-C toxin.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: December 28, 2004
    Assignee: Regents of the University of Minnesota
    Inventors: Patrick M. Schlievert, Douglas Ohlendorf, David T. Mitchell, Pamala J. Gahr
  • Mutants of streptococcal toxin C and methods of use
    Patent number: 6774218
    Abstract: This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-C toxin. The mutant SPE-C toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-C toxin.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: August 10, 2004
    Assignee: Regents of the University of Minnesota
    Inventors: Patrick M. Schlievert, Douglas Ohlendorf, David T. Mitchell, Pamela Gahr
  • Mutants of streptococcal toxin a and methods of use
    Patent number: 6632441
    Abstract: This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: October 14, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Patrick M. Schlievert, Manuela Roggiani, Jennifer Stoehr, Douglas Ohlendorf
  • MUTANTS OF STREPTOCOCCAL TOXIN A AND METHODS OF USE
    Publication number: 20020086813
    Abstract: This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
    Type: Application
    Filed: August 4, 1999
    Publication date: July 4, 2002
    Applicant: Regents of the University of Minnesota
    Inventors: PATRICK M. SCHLIEVERT, MANUELA ROGGIANI, JENNIFER STOEHR AUGE, DOUGLAS OHLENDORF
  • MUTANTS OF STREPTOCOCCAL TOXIN A AND METHODS OF USE
    Publication number: 20020054887
    Abstract: This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
    Type: Application
    Filed: March 12, 1998
    Publication date: May 9, 2002
    Applicant: Regents of the University of Minnesota
    Inventors: PATRICK M SCHLIEVERT, MANUELA ROGGIANI, JENNIFER STOEHR, DOUGLAS OHLENDORF
  • MUTANTS OF STREPTOCOCCAL TOXIN C AND METHODS OF USE
    Publication number: 20020039585
    Abstract: This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-C toxin. The mutant SPE-C toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-C toxin.
    Type: Application
    Filed: July 14, 1999
    Publication date: April 4, 2002
    Applicant: MERCHANT & GOULD
    Inventors: PATRICK M SCHLIEVERT, DOUGLAS OHLENDORF, DAVID T MITCHELL, PAMALA J GAHR
  • MUTANTS OF STREPTOCOCCAL TOXIN C AND METHODS OF USE
    Publication number: 20020018781
    Abstract: This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-C toxin. The mutant SPE-C toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-C toxin.
    Type: Application
    Filed: June 18, 1999
    Publication date: February 14, 2002
    Applicant: MERCHANT AND GOULD
    Inventors: PATRICK M. SCHLIEVERT, DOUGLAS OHLENDORF, DAVID T. MITCHELL, PAMELA GAHR