Patents by Inventor Douglas R. Hole

Douglas R. Hole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180250329
    Abstract: Methods and devices for treating excess mucus accumulation in mammals by administering gaseous inhaled nitric oxide or nitric oxide releasing compounds as a mucolytic agent or expectorant are provided. Delivery of gaseous nitric oxide can be made nasally or orally and is preferably substantially coincident with inhalation of the mammal or based on a synchronous parameter of the mammal's respiratory cycle. Varying therapeutic profiles may be used for the delivery of gaseous nitric oxide depending on the severity of the excess mucus accumulation. Parameters for the therapeutic profiles may include flow rate of nitric oxide containing gas, duration of administration of nitric oxide containing gas, number of breaths for which nitric oxide containing gas is to be administered, and concentrations of therapeutic NO delivered to the airways.
    Type: Application
    Filed: January 31, 2018
    Publication date: September 6, 2018
    Inventors: Bruce R. Murray, Christopher C. Miller, Douglas R. Hole, Bryan Perry
  • Publication number: 20160194766
    Abstract: Devices and methods are described for converting a carbon source and a hydrogen source into hydrocarbons, such as alcohols, for alternative energy sources. The influents may comprise carbon dioxide gas and hydrogen gas or water, obtainable from the atmosphere for through methods described herein, such as plasma generation or electrolysis. One method to produce hydrocarbons comprises the use of an electrolytic device, comprising an anode, a cathode and an electrolyte. Another method comprises the use of ultrasonic energy to drive the reaction. The devices and methods and related devices and methods are useful, for example, to provide a fossil fuel alternative energy source, store renewable energy, sequester carbon dioxide from the atmosphere, counteract global warming, and store carbon dioxide in a liquid fuel.
    Type: Application
    Filed: March 15, 2016
    Publication date: July 7, 2016
    Inventors: Craig D. Eastman, Douglas R. Hole
  • Patent number: 9315910
    Abstract: Devices and methods are described for converting a carbon source and a hydrogen source into hydrocarbons, such as alcohols, for alternative energy sources. The influents may comprise carbon dioxide gas and hydrogen gas or water, obtainable from the atmosphere for through methods described herein, such as plasma generation or electrolysis. One method to produce hydrocarbons comprises the use of an electrolytic device, comprising an anode, a cathode and an electrolyte. Another method comprises the use of ultrasonic energy to drive the reaction. The devices and methods and related devices and methods are useful, for example, to provide a fossil fuel alternative energy source, store renewable energy, sequester carbon dioxide from the atmosphere, counteract global warming, and store carbon dioxide in a liquid fuel.
    Type: Grant
    Filed: August 28, 2012
    Date of Patent: April 19, 2016
    Assignee: Principle Energy Solutions Inc.
    Inventors: Craig D. Eastman, Douglas R. Hole
  • Publication number: 20140141098
    Abstract: Methods and devices for treating excess mucus accumulation in mammals by administering gaseous inhaled nitric oxide or nitric oxide releasing compounds as a mucolytic agent or expectorant are provided. Delivery of gaseous nitric oxide can be made nasally or orally and is preferably substantially coincident with inhalation of the mammal or based on a synchronous parameter of the mammal's respiratory cycle. Varying therapeutic profiles may be used for the delivery of gaseous nitric oxide depending on the severity of the excess mucus accumulation. Parameters for the therapeutic profiles may include flow rate of nitric oxide containing gas, duration of administration of nitric oxide containing gas, number of breaths for which nitric oxide containing gas is to be administered, and concentrations of therapeutic NO delivered to the airways.
    Type: Application
    Filed: August 26, 2013
    Publication date: May 22, 2014
    Applicant: Pulmonox Technologies Corporation
    Inventors: Bruce R. Murray, Christopher C. Miller, Douglas R. Hole
  • Patent number: 8518457
    Abstract: Methods and devices for treating excess mucus accumulation in mammals by administering gaseous inhaled nitric oxide or nitric oxide releasing compounds as a mucolytic agent or expectorant are provided. Delivery of gaseous nitric oxide can be made nasally or orally and is preferably substantially coincident with inhalation of the mammal or based on a synchronous parameter of the mammal's respiratory cycle. Varying therapeutic profiles may be used for the delivery of gaseous nitric oxide depending on the severity of the excess mucus accumulation. Parameters for the therapeutic profiles may include flow rate of nitric oxide containing gas, duration of administration of nitric oxide containing gas, number of breaths for which nitric oxide containing gas is to be administered, and concentrations of therapeutic NO delivered to the airways.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: August 27, 2013
    Assignee: Pulmonox Technologies Corporation
    Inventors: Christopher C. Miller, Douglas R. Hole, Bruce R Murray, Bryan Perry
  • Publication number: 20120329657
    Abstract: Devices and methods are described for converting a carbon source and a hydrogen source into hydrocarbons, such as alcohols, for alternative energy sources. The influents may comprise carbon dioxide gas and hydrogen gas or water, obtainable from the atmosphere for through methods described herein, such as plasma generation or electrolysis. One method to produce hydrocarbons comprises the use of an electrolytic device, comprising an anode, a cathode and an electrolyte. Another method comprises the use of ultrasonic energy to drive the reaction. The devices and methods and related devices and methods are useful, for example, to provide a fossil fuel alternative energy source, store renewable energy, sequester carbon dioxide from the atmosphere, counteract global warming, and store carbon dioxide in a liquid fuel.
    Type: Application
    Filed: August 28, 2012
    Publication date: December 27, 2012
    Applicant: PRINCIPLE ENERGY SOLUTIONS, INC.
    Inventors: Craig D. Eastman, Douglas R. Hole
  • Patent number: 8277631
    Abstract: Devices and methods are described for converting a carbon source and a hydrogen source into hydrocarbons, such as alcohols, for alternative energy sources. The influents may comprise carbon dioxide gas and hydrogen gas or water, obtainable from the atmosphere for through methods described herein, such as plasma generation or electrolysis. One method to produce hydrocarbons comprises the use of an electrolytic device, comprising an anode, a cathode and an electrolyte. Another method comprises the use of ultrasonic energy to drive the reaction. The devices and methods and related devices and methods are useful, for example, to provide a fossil fuel alternative energy source, store renewable energy, sequester carbon dioxide from the atmosphere, counteract global warming, and store carbon dioxide in a liquid fuel.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: October 2, 2012
    Assignee: Principle Energy Solutions, Inc.
    Inventors: Craig D. Eastman, Douglas R. Hole
  • Publication number: 20120186635
    Abstract: Devices and methods are described for more effectively collecting solar energy, including both visible and non-visible electromagnetic radiation to be converted into electrical energy. For example, a nanotube/nanowire device, comprising an electrical contact layer, semi-conductive layer, insulating layer, source electrode, drain electrode and semi-conducting nanotubes/nanowires can be used to collect solar energy from the UV to the infrared electromagnetic spectrum. Another example comprises a device that is capable of adjusting its frequency response to maximize power output according to the wavelength of electromagnetic radiation present. These devices and related methods are useful, for example, to provide an alternative electrical energy source, harness unused renewable energy, reduce carbon dioxide emissions, counteract global warming, and provide a carbon neutral energy source.
    Type: Application
    Filed: January 26, 2012
    Publication date: July 26, 2012
    Inventors: Craig D. Eastman, Douglas R. Hole
  • Publication number: 20120118287
    Abstract: Gas packages for the delivery of therapeutic gases, and in particular gaseous nitric oxide (gNO) are provided herein. The gas packages comprise one or more of a gas reservoir, interface layer, sealing layer, and holding container. The interface layer regulates discharge of the therapeutic gas from the gas reservoir to the external environment. The sealing layer and/or holding container prevent evolution of the gas until the sealing layer is compromised or the holding container is opened.
    Type: Application
    Filed: November 4, 2011
    Publication date: May 17, 2012
    Applicant: PULMONOX TECHNOLOGIES CORPORATION
    Inventors: Douglas R. Hole, Curtis Figley, Robert E. Lee, Michael Hudec, Robert Rolfson
  • Patent number: 8079998
    Abstract: Gas packages for the delivery of therapeutic gases, and in particular gaseous nitric oxide (gNO) are provided herein. The gas packages comprise one or more of a gas reservoir, interface layer, sealing layer, and holding container. The interface layer regulates discharge of the therapeutic gas from the gas reservoir to the external environment. The sealing layer and/or holding container prevent evolution of the gas until the sealing layer is compromised or the holding container is opened. The gas packages and methods for using them are useful for the treatment, alleviation, and prevention of various disease and non-disease, medical and non-medical, conditions in humans and animals.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: December 20, 2011
    Assignee: Pulmonox Technologies Corporation
    Inventors: Douglas R. Hole, Curtis Figley, Robert E. Lee, Michael Hudec, Robert Rolfson
  • Publication number: 20080283411
    Abstract: Devices and methods are described for converting a carbon source and a hydrogen source into hydrocarbons, such as alcohols, for alternative energy sources. The influents may comprise carbon dioxide gas and hydrogen gas or water, obtainable from the atmosphere for through methods described herein, such as plasma generation or electrolysis. One method to produce hydrocarbons comprises the use of an electrolytic device, comprising an anode, a cathode and an electrolyte. Another method comprises the use of ultrasonic energy to drive the reaction. The devices and methods and related devices and methods are useful, for example, to provide a fossil fuel alternative energy source, store renewable energy, sequester carbon dioxide from the atmosphere, counteract global warming, and store carbon dioxide in a liquid fuel.
    Type: Application
    Filed: May 5, 2008
    Publication date: November 20, 2008
    Inventors: Craig D. Eastman, Douglas R. Hole
  • Publication number: 20080193566
    Abstract: The invention relates to a methods and devices of delivering gaseous nitric oxide to a mammal or surface at a concentration ranging from about 1000 ppm to about 50,000 ppm of gaseous nitric oxide. Different conditions which can be treated by high dosage administration of gNO include but are not limited to: topical treatments with gNO, cosmetic applications of gNO, vasodilation conditions with gNO, inhalation treatments with gNO, treatments of the blood with gNO, treatment of the skin or tissue with gNO, treatment of infections with gNO, treatment of inflammation on or within the body, and treatments of biofilms with gNO. Other conditions, aliments, or symptoms that may be treated with high dosage gNO include bronchoconstriction, reversible pulmonary vasoconstriction, asthma, pulmonary hypertension, adult respiratory distress syndrome (ARDS), and persistent pulmonary hypertension of the newborn (PPHN).
    Type: Application
    Filed: February 9, 2007
    Publication date: August 14, 2008
    Inventors: Christopher C. Miller, Douglas R. Hole, Robert E. Lee
  • Publication number: 20020138051
    Abstract: A system and a method topically applies nitric oxide to an infected area of tissue to treat a wound or lesion to prevent infection, reduce pathogen levels in the infected area and promote healing. The basic system includes a source of nitric oxide gas and a flushing envelope. The flushing envelope is applied to an animal to cover a wound and receives nitric oxide from the source via a flow control valve. One form of the system includes a vacuum unit fluidically connected to the flushing envelope, and one embodiment includes a gas absorber unit. The flushing envelope is adapted to surround the area of the infected tissue and form a substantially air-tight seal with the tissue surface when the flushing envelope is in place on the animal. The flow control valve controls the amount and concentration of nitric oxide gas that is delivered to the flushing envelope.
    Type: Application
    Filed: March 26, 2001
    Publication date: September 26, 2002
    Inventors: Douglas R. Hole, Cortis Figley, Christopher C. Miller, Alex Stenller