Abstract: Disclosed are compositions, vectors, and methods for treating and preventing rabies lyssavirus infection in a subject in need thereof, including rabies lyssavirus encephalitis. The disclosed compositions relate to anti-rabies immunoglobulins and vectors for expressing anti-rabies immunoglobulins such as adeno-associated virus (AAV) vectors that express anti-rabies immunoglobulins in a subject in need thereof. In some embodiments, the disclosed methods relate to treating and/or preventing an infection by rabies lyssavirus in a subject in need thereof, the methods comprising administering to the subject a dose of an adeno-associated virus (AAV) vector that expresses an immunoglobulin that binds and neutralizes rabies lyssavirus in the subject.

Abstract: Provided herein are MRI contrast agents that are conditionally activated by an enzyme from a reporter gene coupled to a gene of interest. In some embodiments, provided herein is a platform where a substrate (blocking access of water to a Gd(III) ion) is removed by an enzyme that can be changed to accommodate a number of gene therapy targets.

Abstract: An aerial image relates to a geographic area. The aerial image is analyzed to identify at least one traffic signal in the geographic area. Based at least in part on analyzing the aerial image, a timing prediction is determined for the at least one traffic signal.

Abstract: A method for controlling a powersplit transmission includes connecting an engine to the transmission, provided an engine torque request is present; connecting a motor to the transmission, provided an engine torque request is absent and the engine is on; and disconnecting the engine and motor from the transmission, provided the engine is off, and using a traction motor to produce wheel torque.

Abstract: A monitoring device receives an aerial image, data relating to a vehicle and a request for an image of the vehicle. The vehicle is located in the image. A portion of the aerial image that includes the vehicle and/or information based thereon is provided.

Abstract: A monitoring device receives an aerial image, data relating to a vehicle and a request for an image of the vehicle. The vehicle is located in the image. A portion of the aerial image that includes the vehicle and/or information based thereon is provided.

Abstract: An aerial image relates to a geographic area. The aerial image is analyzed to identify at least one traffic signal in the geographic area. Based at least in part on analyzing the aerial image, a timing prediction is determined for the at least one traffic signal.

Abstract: An aerial image is received. A portion of the aerial image is identified that represents an area of interest that includes a vehicle. The portion of the aerial image is analyzed to generate an identification of one or more objects in the area of interest related to a route of the vehicle.

Abstract: A computer in a vehicle is configured to receive one or more data collector inputs, detect an object proximate to the vehicle based on the one or more inputs, determine a closure speed between the object and the vehicle, determine a change in speed of the object, compute an accountability factor; and determine whether to identify a potential incident based at least in part on the accountability factor and an incident value. The incident value is a function of at least one of the closure speed and a distance between the vehicle and the object. The accountability factor is based at least in part on the closure speed and the change in speed of the object.

Abstract: A powertrain includes a gearset including a sun gear, a carrier, a ring gear connected to a countershaft, pinions supported on the carrier and meshing with the sun gear and ring gear; a second gearset connectable to an engine, for overdriving a generator; a clutch for releasably connecting the engine and carrier; a second clutch for releasably connecting the sun gear and the generator; and a motor connected to a countershaft. Operation of the powertrain can be readily switched between powersplit mode and series mode.

Abstract: A powertrain includes a gearset including a sun gear, a carrier, a ring gear connected to a countershaft, pinions supported on the carrier and meshing with the sun gear and ring gear; a second gearset connectable to an engine, for overdriving a generator; a clutch for releasably connecting the engine and carrier; a second clutch for releasably connecting the sun gear and the generator; and a motor connected to a countershaft. Operation of the powertrain can be readily switched between powersplit mode and series mode.

Abstract: The invention comprises a control method for a hybrid electric vehicle powertrain having a throttle-controlled engine and an electric motor, a battery and a generator. Compensation is made for differences between driver commanded torque and actual engine torque due to engine throttle contamination using a closed-loop control strategy that creates a throttle setting correction.

Abstract: Methods and systems for mining large data sets using block model averaging techniques are provided. Example embodiments provide a Block Model Averaging System (“BMAS”), which enables users to build/train, test, deploy, and maintain predictive statistical models that can be used to gain knowledge from both static and dynamic data. In one embodiment, the BMAS incrementally builds predictive models from portions (blocks) of input data using block model averaging techniques, determines a voting population of the predictive models to use as components of an ensemble model, generates an ensemble model with these determined components, and deploys the generated ensemble model to input data to derive answers. One technique for determining the voting population is correctness; another is diversity of response.

Abstract: A moldable detergent having a stable available halogen concentration suitable for use in industrial and institutional dishwashers is produced in a process which comprises:admixing an alkali metal polyphosphate compound, an alkali metal silicate compound, and an aqueous solution of an available halogen compound to form an available halogen containing mixture, andadmixing an alkali metal phosphate compound to produce a moldable detergent composition containing at least 50 percent by weight of solids and having an available halogen concentration of at least about 1 percent by weight.