Abstract: A dialysis system includes a dialysis machine comprising a motorized autoconnection mechanism, a fluid supply line connected to a source of dialysis fluid, and a cassette for use with the dialysis machine. The cassette includes a frame, a pump chamber within the frame, a first set of valves for routing the dialysis fluid from the fluid supply line to the pump chamber, and a second set of valves for routing the dialysis fluid from the pump chamber to a patient line. The cassette also includes a plurality of ports communicating with the first and second set of valves. Each port includes an integral spike. The motorized autoconnection mechanism is configured to move the fluid supply line and the patient line automatically so as to be spiked open respectively by the plurality of ports of the cassette.

Abstract: A dialysis system including a disposable fluid pumping cassette including at least one flexible membrane attached to a housing and at least one port extending from the housing, the at least one port including a spike; at least one dialysis fluid supply in fluid communication with at least one tubing and tubing connector; an autoconnection device including a shuttle for moving the at least one tubing and tubing connector towards the spike of the at least one port, the autoconnection device including at least one lead screw in mechanical communication with the shuttle, a motor and power transmission equipment to transmit power from the motor to the at least one lead screw; and a controller programmed to operate the motor to move the at least one tubing and tubing connector towards the spike of the at least one port of the disposable fluid pumping cassette.

Abstract: A dialysis system including a disposable fluid pumping cassette including at least one flexible membrane attached to a housing and at least one port extending from the housing, the at least one port including a spike; at least one dialysis fluid supply in fluid communication with at least one tubing and tubing connector; an autoconnection device including a shuttle for moving the at least one tubing and tubing connector towards the spike of the at least one port, the autoconnection device including at least one lead screw in mechanical communication with the shuttle, a motor and power transmission equipment to transmit power from the motor to the at least one lead screw; and a controller programmed to operate the motor to move the at least one tubing and tubing connector towards the spike of the at least one port of the disposable fluid pumping cassette.

Abstract: A dialysis system including a disposable fluid pumping cassette including at least one flexible membrane attached to a housing and at least one port extending from the housing, the at least one port including a spike; at least one dialysis fluid supply in fluid communication with at least one tubing and tubing connector; an autoconnection device including a shuttle for moving the at least one tubing and tubing connector towards the spike of the at least one port, the autoconnection device including at least one lead screw in mechanical communication with the shuttle, a motor and power transmission equipment to transmit power from the motor to the at least one lead screw; and a controller programmed to operate the motor to move the at least one tubing and tubing connector towards the spike of the at least one port of the disposable fluid pumping cassette.

Abstract: A system for automatically connecting tubing to a medical fluid machine includes at least one fluid container including a tube having a cap on an end of the tube, a shuttle configured to receive the tube, a driving mechanism configured to translate the shuttle, a cap removal device configured to remove the cap from the end of the tube, and a control unit programmed to cause (i) the driving mechanism to translate the shuttle holding the tube in a first direction towards the cap removal device so that the cap removal device can engage the tube cap, (ii) the driving mechanism to translate in a second direction away from the cap removal device so that the cap removal device removes the cap from the end of the tube, and (iii) the driving mechanism to translate the shuttle in the first direction with the cap removed from the tube so that the tube can be mated with the medical fluid machine.

Abstract: A dialysis system including a disposable fluid pumping cassette including at least one flexible membrane attached to a housing and at least one port extending from the housing, the at least one port including a spike; at least one dialysis fluid supply in fluid communication with at least one tubing and tubing connector; an autoconnection device including a shuttle for moving the at least one tubing and tubing connector towards the spike of the at least one port, the autoconnection device including at least one lead screw in mechanical communication with the shuttle, a motor and power transmission equipment to transmit power from the motor to the at least one lead screw; and a controller programmed to operate the motor to move the at least one tubing and tubing connector towards the spike of the at least one port of the disposable fluid pumping cassette.

Abstract: A dialysis system includes a dialysis machine including at least one fluid pump, and an autoconnection mechanism including a moveable holder; a plurality of pierceable connectors each held by the moveable holder of the autoconnection mechanism, each of the pierceable connectors in fluid communication with a source of medical fluid; a plurality of spikes each held fixed by the dialysis machine, each of the spikes in fluid communication with a disposable component that is positioned and arranged to operate with the at least one fluid pump; and wherein the moveable holder is moved automatically by the autoconnection mechanism, so that (i) the spikes pierce the pierceable connectors and (ii) the sources of medical fluid can communicate with the disposable component positioned and arranged to operate with the at least one fluid pump.

Abstract: A medical fluid system including: fluid containers and a tube extending from same, each tube including a cap; a pumping cassette including port spikes; a medical fluid machine including: occluders; a shuttle configured to receive the tubes, wherein each tube is associated with one of the occluders; a driving mechanism translating the shuttle; a cap removal device between the cassette and the shuttle; and a control unit programmed to cause: (i) the occluders to pinch their tubes, (ii) cause the driving mechanism to translate the shuttle towards the fluid pumping cassette, the cap removal device engaging the tube caps, (iii) the driving mechanism to translate the shuttle away from the fluid pumping cassette and cap removal device, pulling the tube caps off of the tubes, and (iv) the driving mechanism to translate the shuttle back towards the fluid pumping cassette for the port spikes to spike the occluded tubes.

Abstract: A system for automatically connecting tubing to a medical fluid machine includes at least one fluid container including a tube having a cap on an end of the tube, a shuttle configured to receive the tube, a driving mechanism configured to translate the shuttle, a cap removal device configured to remove the cap from the end of the tube, and a control unit programmed to cause (i) the driving mechanism to translate the shuttle holding the tube in a first direction towards the cap removal device so that the cap removal device can engage the tube cap, (ii) the driving mechanism to translate in a second direction away from the cap removal device so that the cap removal device removes the cap from the end of the tube, and (iii) the driving mechanism to translate the shuttle in the first direction with the cap removed from the tube so that the tube can be mated with the medical fluid machine.

Abstract: A medical fluid autoconnection method includes: enabling acceptance a pierceable connector that is capable of fluidly communicating with a source of medical fluid into a moveable holder; temporarily fixing a spike to a medical fluid pumping machine; automatically detecting whether the pierceable connector has been placed into the moveable holder; if the pierceable connector is sensed as being placed in the moveable holder, moving the holder so that the spike pierces the pierceable connector; and enabling medical fluid to be pumped from the source through the connected spiked and connector.

Abstract: A fluid dispensing machine, such as a peritoneal dialysis or hemodialysis machine, includes a dispenser or cassette that pumps a medical fluid for dialysis or other treatments for patients. The machine includes and uses an autoconnect device for connecting containers of liquid, such as bags of dialysis fluid or medication fluids, to the machine, while maintaining the sterility of the connection. The autoconnect device removes the cap from the fluid bag and pierces a sealing membrane on tubing from the bag. This makes it easier for patients to receive treatment, especially home treatment. The cassettes preferably have tubing ports with integral spikes for piercing the membrane on tubing from bags of liquids. The ports may be staggered for sequential engagement with the spikes. Other embodiments are useful for dispensing other liquids from other types of dispensing or pumping machines.

Abstract: A medical fluid machine with supply autoconnection, the machine comprising: a cassette-receiving wall; a disposable cassette held firmly by the wall, the disposable cassette including a port spike, the port spike fitted with a spike cap; a translating shuttle including a channel sized to hold a portion of a supply tube and including a fixture for releasably holding a supply tube end; a supply tube including an end configured to be releasably held by the fixture of the channel of the translating shuttle, the supply tube fitted with a supply tube cap; a cap removal device selectively positionable between the disposable cassette and the translating shuttle; and a controller programmed to (i) translate the shuttle holding the supply tube at the supply tube end towards the disposable cassette, so that the cap removal device is likewise moved towards the disposable cassette and the spike cap of the disposable cassette is engaged, (ii) translate the shuttle holding the supply tube at the supply tube end away from th

Abstract: A medical fluid autoconnection method includes: enabling acceptance a pierceable connector that is capable of fluidly communicating with a source of medical fluid into a moveable holder; temporarily fixing a spike to a medical fluid pumping machine; automatically detecting whether the pierceable connector has been placed into the moveable holder; if the pierceable connector is sensed as being placed in the moveable holder, moving the holder so that the spike pierces the pierceable connector; and enabling medical fluid to be pumped from the source through the connected spiked and connector.

Abstract: A dialysis system includes a dialysis machine including at least one fluid pump, and an autoconnection mechanism including a moveable holder; a plurality of pierceable connectors each held by the moveable holder of the autoconnection mechanism, each of the pierceable connectors in fluid communication with a source of medical fluid; a plurality of spikes each held fixed by the dialysis machine, each of the spikes in fluid communication with a disposable component that is positioned and arranged to operate with the at least one fluid pump; and wherein the moveable holder is moved automatically by the autoconnection mechanism, so that (i) the spikes pierce the pierceable connectors and (ii) the sources of medical fluid can communicate with the disposable component positioned and arranged to operate with the at least one fluid pump.

Abstract: A medical fluid machine with supply autoconnection, the machine comprising: a cassette-receiving wall; a disposable cassette held firmly by the wall, the disposable cassette including a port spike, the port spike fitted with a spike cap; a translating shuttle including a channel sized to hold a portion of a supply tube and including a fixture for releasably holding a supply tube end; a supply tube including an end configured to be releasably held by the fixture of the channel of the translating shuttle, the supply tube fitted with a supply tube cap; a cap removal device selectively positionable between the disposable cassette and the translating shuttle; and a controller programmed to (i) translate the shuttle holding the supply tube at the supply tube end towards the disposable cassette, so that the cap removal device is likewise moved towards the disposable cassette and the spike cap of the disposable cassette is engaged, (ii) translate the shuttle holding the supply tube at the supply tube end away from th

Abstract: A fluid dispensing machine, such as a peritoneal dialysis or hemodialysis machine, includes a dispenser or cassette that pumps a medical fluid for dialysis or other treatments for patients. The machine includes and uses an autoconnect device for connecting containers of liquid, such as bags of dialysis fluid or medication fluids, to the machine, while maintaining the sterility of the connection. The autoconnect device removes the cap from the fluid bag and pierces the scaling membrane on tubing from the bag. This makes it easier for patients to receive treatment, especially home treatment. Other embodiments are useful for dispensing other liquids from other types of dispensing or pumping machines.

Abstract: A disposable pumping cassette in one embodiment includes a pump chamber; and a valve chamber in communication with the pump chamber, the valve chamber including an inlet and first and second outlets. A disposable pumping cassette in another embodiment includes a first valve chamber including an inlet and first and second outlets; and a second valve chamber including an inlet and an outlet, the second valve chamber openable to allow dialysis fluid to flow through one of the first and second outlets of the first valve chamber, through the outlet of the second valve chamber. A disposable pumping cassette in a further embodiment includes a valve chamber including a fluid inlet and first and second fluid outlets; and a flexible sheet openable to open and close only one of the first and second outlets.

Abstract: A medical fluid machine, such as a dialysis machine, includes a pump that pumps a medical fluid and sterile water or other disinfecting liquid, such as ozonated water, for flushing and reconditioning the medical fluid machine. The machine may also include a heater that heats the medical fluid or disinfecting solution in order to kill bacteria and other microorganisms that may contaminate the machine after use. Disinfecting the machine, and a disposable kit used with the machine, may allow re-use of the disposable within a reasonable amount of time after completion of the disinfecting procedure. Dialysate treated with ultra-violet light or water with low concentrations of ozone also helps make the disposable kits suitable for reuse.

Abstract: A fluid dispensing machine, such as a peritoneal dialysis or hemodialysis machine, includes a dispenser or cassette that pumps a medical fluid for dialysis or other treatments for patients. The machine includes and uses an autoconnect device for connecting containers of liquid, such as bags of dialysis fluid or medication fluids, to the machine, while maintaining the sterility of the connection. The autoconnect device removes the cap from the fluid bag and pierces a sealing membrane on tubing from the bag. This makes it easier for patients to receive treatment, especially home treatment. The cassettes preferably have tubing ports with integral spikes for piercing the membrane on tubing from bags of liquids. The ports may be staggered for sequential engagement with the spikes. Other embodiments are useful for dispensing other liquids from other types of dispensing or pumping machines.

Abstract: A medical fluid machine, such as a dialysis machine, includes a pump that pumps a medical fluid and sterile water or other disinfecting liquid, such as ozonated water, for flushing and reconditioning the medical fluid machine. The machine may also include a heater that heats the medical fluid or disinfecting solution in order to kill bacteria and other microorganisms that may contaminate the machine after use. Disinfecting the machine, and a disposable kit used with the machine, may allow re-use of the disposable within a reasonable amount of time after completion of the disinfecting procedure. Dialysate treated with ultra-violet light or water with low concentrations of ozone also helps make the disposable kits suitable for reuse.