Patents by Inventor Douglas S. Reintgen

Douglas S. Reintgen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of determining melanoma micrometastasis using tyrosinase
    Patent number: 6153388
    Abstract: A highly sensitive method to detect melanoma micrometastasis by examining lymph nodes for the presence of tyrosinase messenger RNA. In a preferred mode, this is accomplished using the combination of reverse transcription and double round polymerase chain reaction (RT-PCR). The amplified samples are examined on a 2% agarose gel and tyrosinase is seen as a 207 base pair fragment. The lymph nodes examined are determined using pre- and intra- operative node mapping.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: November 28, 2000
    Assignee: University of South Florida
    Inventor: Douglas S. Reintgen