Abstract: The disclosure herein relates to isolated and purified mammalian fetal allografts and kits and compositions containing these. Also disclosed are methods of preparing isolated and purified mammalian fetal allografts; methods of contacting a wound of a subject with these, and methods of treating a disease or condition with these.

Abstract: A joint prosthesis comprising, e.g., a femoral component and a tibial component. The medial and lateral condylar articular surfaces may have substantially uniform and equal radii from full extension to about 90° of flexion. From 90°, the lateral condylar articular surface has a smaller radius than the medial condylar articular surface such that the medial condyle gradually becomes increasingly more proud than the lateral condyle to facilitate internal rotation of the tibia at deep flexion. Also, the tibial articular component may include a post intermediate the medial and lateral compartments that engages a cam on the femoral articular component between the medial and the lateral condylar articular surfaces. The cam and post become congruent at flexion angles of approximately 70° flexion and mate symmetrically during the first 20°-30° of further flexion, and then mate asymmetrically at greater degrees of flexion to force internal rotation of the tibia.

Abstract: A joint prosthesis includes e.g., a femoral component and a tibial component. The medial and lateral condylar articular surfaces may have substantially uniform and equal radii from full extension to about 90° of flexion. From 90°, the lateral condylar articular surface has a smaller radius than the medial condylar articular surface such that the medial condyle gradually becomes increasingly more proud than the lateral condyle to facilitate internal rotation of the tibia at deep flexion. Also, the tibial articular component may include a post intermediate the medial and lateral compartments that engages a cam on the femoral articular component between the medial and the lateral condylar articular surfaces. The cam and post become congruent at flexion angles of approximately 70° flexion and mate symmetrically during the first 20°-30° of further flexion, and then mate asymmetrically at greater degrees of flexion to force internal rotation of the tibia.

Abstract: A joint prosthesis comprising, e.g., a femoral component and a tibial component. The medial and lateral condylar articular surfaces may have substantially uniform and equal radii from full extension to about 90° of flexion. From 90°, the lateral condylar articular surface has a smaller radius than the medial condylar articular surface such that the medial condyle gradually becomes increasingly more proud than the lateral condyle to facilitate internal rotation of the tibia at deep flexion. Also, the tibial articular component may include a post intermediate the medial and lateral compartments that engages a cam on the femoral articular component between the medial and the lateral condylar articular surfaces. The cam and post become congruent at flexion angles of approximately 70° flexion and mate symmetrically during the first 20°-30° of further flexion, and then mate asymmetrically at greater degrees of flexion to force internal rotation of the tibia.

Abstract: The present invention relates to functional, modified glucose-galactose binding proteins (GGBPs), that have a greater melting temperature (Tm) than a reference GGBP. The present invention also relates to biological sensors, e.g., glucose sensors, comprising these thermostable GGBPs. The present invention also relates to nucleic acids encoding these thermostable GGBPs.

Abstract: The invention is directed to compositions of mutated binding proteins containing reporter groups, analyte biosensor devices derived therefrom, and their use as analyte biosensors both in vitro and in vivo.

Abstract: A compact, vehicle-mounted antenna (10) is disclosed. In one embodiment, a first and second antenna elementS (30, 40) are positioned on a conductive ground plane (FIG. 1). The antenna elements can comprise platforms supported by a ground (34) and a feed (36). The antenna elements can be tuned to various bands (e.g., cellular of PCS). At least one additional antenna element (e.g., a GPS receive antenna (60)) can be positioned between the two antenna elements. One of the feeds of the antenna elements can be angled so that the antenna element has a desired height (e.g., a height matching the other antenna element). The antenna elements can be electrically connected to a transmission line (116) via a single feed line.

Abstract: Reactive fluorescent dyes compositions and methods of using same are disclosed. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed having thiol-reactive groups. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed that exhibit a fluorescence emission of at least about 575 nm. Biosensors are disclosed having a binding protein and a squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus.

Abstract: The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins. Many of the peptides of the invention may be produced in large quantity by recombinant techniques and formulated in culture medium to produce the desired effect on cultured cells and tissues. Certain of the libraries of the invention and the peptides identified in them are particularly useful in concatemer-based recombinant expression methods.

Abstract: A child safety, folding seat includes support members pivotally joined to a seat member. The seat member pivots between folded and unfolded conditions, and a lock locks the seat in the unfolded condition when the seat members is unfolded. Preferably, the lock is spaced rearwardly on an underside of the horizontal seat member sufficiently so that a child on the seat will not normally be able to reach under the seat and inadvertently disengage the lock and the lock automatically locks when the seat member is pivoted to the horizontal position.

Abstract: A compact, vehicle-mounted antenna is disclosed. In one embodiment, a first and second antenna element are positioned on a conductive ground plane. The antenna elements can comprise platforms supported by a ground and a feed. The antenna elements can be tuned to various bands (e.g., cellular or PCS). At least one additional antenna element (e.g., a GPS receive antenna) can be positioned between the two antenna elements. One of the feeds of the antenna elements can be angled so that the antenna element has a desired height (e.g., a height matching the other antenna element). The antenna elements can be electrically connected to a transmission line via a single feed line.

Abstract: The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins. Many of the peptides of the invention may be produced in large quantity by recombinant techniques and formulated in culture medium to produce the desired effect on cultured cells and tissues. Certain of the libraries of the invention and the peptides identified in them are particularly useful in concatemer-based recombinant expression methods.

Abstract: A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. An optical conduit, preferably an optical fiber has an optical system at the proximal end of the optical conduit. A sensing element is attached to the distal end of the optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the sensing element includes reference groups with luminescence properties that are substantially unchanged by variations in the analyte concentrations.

Abstract: Storage organization of data according to business objectives is provided to manage data storage consumption among data storage consumers. Data is not managed at the file level, but organized, coordinated and enforced at a global level based on business logic. The business objectives typically include customer information, priority information, marketing information, manufacturing information, recorded contract and documentary information or information regarding the revenue generation or potential of data. The logical representation enforces data storage consumers to work according to the definitions in the logical representation. The data storage consumers will have the opportunity to define storage parameters for each of the data defined in the logical representation. The placement and determination of where the data should be stored is accomplished according to these defined storage parameters.

Abstract: The invention is directed to compositions of mutated binding proteins containing reporter groups, analyte biosensor devices derived therefrom, and their use as analyte biosensors both in vitro and in vivo.