Patents by Inventor Douglas Sutton

Douglas Sutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240386202
    Abstract: Systems and methods for generative language model tuning can include training the generative language model to generate sets of output text tokens with set of intermediary text tokens with training examples that include input and output pairs. The training can include processing the input with the language model to determine a predicted output and a predicted set of intermediary text tokens. The predicted set of intermediary text tokens can then be evaluated based at least in part on the output associated with the input and the predicted output.
    Type: Application
    Filed: May 2, 2024
    Publication date: November 21, 2024
    Inventors: Matthew Douglas Hoffman, Charles Aloysius Sutton, David Martin Dohan, Sholto Francis Alexandre Douglas, Tuan Anh Le, Van Du Phan, Aaron Thomas Parisi, Ryan Michael Rifkin, Pavel Sountsov, Sharad Vikram
  • Patent number: 12114915
    Abstract: Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.
    Type: Grant
    Filed: March 21, 2024
    Date of Patent: October 15, 2024
    Assignee: May Health US Inc.
    Inventors: Denise Zarins, Neil Barman, Garrett Schwab, Roger Osborne, Douglas Sutton
  • Patent number: 12053373
    Abstract: A heart valve repair device, comprising an atrial-fixation member having an expandable mesh configured to have oval or circular shape in a deployed configuration, the atrial-fixation member defining a central lumen; and a baffle extending from a portion of the atrial-fixation member, the baffle having an anterior portion with a smooth, atraumatic surface configured to coapt with at least a portion of one or more native leaflets of a native heart valve, a posterior portion configured to engage and displace at least a portion of another native leaflet of the native heart valve, wherein the baffle extends radially inward from the atrial-fixation member into the central lumen to approximate a closed position of the displaced native leaflet.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: August 6, 2024
    Assignee: Half Moon Medical, Inc.
    Inventors: Matt McLean, Hanson S. Gifford, III, James I. Fann, Douglas Sutton
  • Publication number: 20240225723
    Abstract: Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.
    Type: Application
    Filed: March 21, 2024
    Publication date: July 11, 2024
    Applicant: May Health US Inc.
    Inventors: Denise ZARINS, Neil BARMAN, Garrett SCHWAB, Roger OSBORNE, Douglas SUTTON
  • Publication number: 20240156491
    Abstract: Medical systems, devices and methods for creation of autologous tissue valves within a mammalian body are disclosed. One example of a device for creating a valve flap from a vessel wall includes an elongate tubular structure having a proximal portion and a distal portion and a longitudinal axis; a first lumen having a first exit port located on the distal portion of the elongate tubular structure; a second lumen having a second exit port located on the distal portion of the elongate tubular structure; a recessed distal surface on the distal portion of the elongate tubular structure, wherein the recessed distal surface is located distally to the first exit port; and an open trough on the recessed distal surface extending longitudinally from the first exit port.
    Type: Application
    Filed: October 10, 2023
    Publication date: May 16, 2024
    Inventors: Fletcher T. Wilson, Douglas Sutton, Christopher Scott Jones, Benjamin K. Cline, Mariel Fabro
  • Patent number: 11974804
    Abstract: Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: May 7, 2024
    Assignee: Medtronic Ireland Manufacturing Unlimited Company
    Inventors: Denise Zarins, Hanson Gifford, III, Mark E. Deem, Douglas Sutton, Howard R. Levin, Mark Gelfand
  • Patent number: 11963714
    Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
    Type: Grant
    Filed: June 14, 2021
    Date of Patent: April 23, 2024
    Assignee: Medtronic Ireland Manufacturing Unlimited Company
    Inventors: Mark E. Deem, Hanson S. Gifford, III, Denise Zarins, Douglas Sutton, Erik Thai, Mark Gelfand, Howard R. Levin
  • Patent number: 11937870
    Abstract: Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: March 26, 2024
    Assignee: May Health US Inc.
    Inventors: Denise Zarins, Neil Barman, Garrett Schwab, Roger Osborne, Douglas Sutton
  • Patent number: 11812990
    Abstract: Medical systems, devices and methods for creation of autologous tissue valves within a mammalian body are disclosed. One example of a device for creating a valve flap from a vessel wall includes an elongate tubular structure having a proximal portion and a distal portion and a longitudinal axis; a first lumen having a first exit port located on the distal portion of the elongate tubular structure; a second lumen having a second exit port located on the distal portion of the elongate tubular structure; a recessed distal surface on the distal portion of the elongate tubular structure, wherein the recessed distal surface is located distally to the first exit port; and an open trough on the recessed distal surface extending longitudinally from the first exit port.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: November 14, 2023
    Assignee: INTERVENE, INC.
    Inventors: Fletcher T. Wilson, Douglas Sutton, Christopher Scott Jones, Benjamin K. Cline, Mariel Fabro
  • Publication number: 20230338282
    Abstract: A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
    Type: Application
    Filed: March 22, 2023
    Publication date: October 26, 2023
    Inventors: Eugene de Juan, Jr., Yair Alster, Steven M. Chamow, Kathleen C. Farinas, Hanson S. Gifford, III, K. Angela Macfarlane, Cary J. Reich, Michael Barrett, Randolph E. Campbell, Robert George, Douglas Sutton
  • Patent number: 11793564
    Abstract: Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.
    Type: Grant
    Filed: January 30, 2023
    Date of Patent: October 24, 2023
    Assignee: May Health US Inc.
    Inventors: Denise Zarins, Neil Barman, Garrett Schwab, Roger Osborne, Douglas Sutton
  • Publication number: 20230233249
    Abstract: Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.
    Type: Application
    Filed: January 30, 2023
    Publication date: July 27, 2023
    Applicant: May Health US Inc.
    Inventors: Denise ZARINS, Neil BARMAN, Garrett SCHWAB, Roger OSBORNE, Douglas SUTTON
  • Patent number: 11642310
    Abstract: A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: May 9, 2023
    Assignee: ForSight Vision4, Inc.
    Inventors: Eugene de Juan, Jr., Yair Alster, Steven M. Chamow, Kathleen Cogan Farinas, Hanson S. Gifford, III, K. Angela Macfarlane, Cary J. Reich, Michael Barrett, Randolph E. Campbell, Robert George, Douglas Sutton
  • Publication number: 20230102547
    Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
    Type: Application
    Filed: May 6, 2022
    Publication date: March 30, 2023
    Inventors: Yair Alster, Eugene de Juan, JR., Cary J. Reich, Stephen Boyd, David Sierra, Jose D. Alejandro, K. Angela Macfarlane, Douglas Sutton
  • Publication number: 20220125579
    Abstract: A heart valve repair device, comprising an atrial-fixation member having an expandable mesh configured to have oval or circular shape in a deployed configuration, the atrial-fixation member defining a central lumen; and a baffle extending from a portion of the atrial-fixation member, the baffle having an anterior portion with a smooth, atraumatic surface configured to coapt with at least a portion of one or more native leaflets of a native heart valve, a posterior portion configured to engage and displace at least a portion of another native leaflet of the native heart valve, wherein the baffle extends radially inward from the atrial-fixation member into the central lumen to approximate a closed position of the displaced native leaflet.
    Type: Application
    Filed: July 1, 2021
    Publication date: April 28, 2022
    Inventors: Matt McLean, Hanson S. Gifford, III, James I. Fann, Douglas Sutton
  • Publication number: 20220079753
    Abstract: Delivery systems for implanting cardiac valve repair devices are disclosed herein. In some embodiments, a delivery system includes a delivery catheter, a hub shaft extending through the delivery catheter, and a core shaft extending through the hub shaft. The delivery catheter is configured to hold a valve repair device in a compressed configuration. The hub shaft includes a hub configured to releasably engage a first portion of the valve repair device, and the core shaft includes a plug configured to releasably engage a second portion of the valve repair device. When the valve repair device is unsheathed from the delivery catheter, the hub shaft and the core shaft are independently movable to axially elongate/compress the valve repair device. When the valve repair device is properly positioned, the hub can be actuated to release the first portion of the valve repair device, and the plug can be actuated to release the second portion of the valve repair device.
    Type: Application
    Filed: March 5, 2021
    Publication date: March 17, 2022
    Inventors: Neil Zimmerman, Jeffrey Martin, Jean-Pierre Dueri, Erik Thai, Andrew Johnston, Douglas Sutton, Cassandra Orth, Robert O'Grady, Jose Gonzalez, Matthew McLean, Gaurav Krishnamurthy
  • Publication number: 20220079755
    Abstract: Delivery systems for implanting cardiac valve repair devices are disclosed herein. In some embodiments, a delivery system includes a delivery catheter, a hub shaft extending through the delivery catheter, and a core shaft extending through the hub shaft. The delivery catheter is configured to hold a valve repair device in a compressed configuration. The hub shaft includes a hub configured to releasably engage a first portion of the valve repair device, and the core shaft includes a plug configured to releasably engage a second portion of the valve repair device. When the valve repair device is unsheathed from the delivery catheter, the hub shaft and the core shaft are independently movable to axially elongate/compress the valve repair device. When the valve repair device is properly positioned, the hub can be actuated to release the first portion of the valve repair device, and the plug can be actuated to release the second portion of the valve repair device.
    Type: Application
    Filed: September 17, 2020
    Publication date: March 17, 2022
    Inventors: Neil Zimmerman, III, Jeffrey Martin, Jean-Pierre Dueri, Erik Thai, Andrew Johnston, Douglas Sutton, Cassandra Orth, Robert O'Grady, Jose Gonzalez, Matthew McLean, Gaurav Krishnamurthy
  • Publication number: 20210330378
    Abstract: Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.
    Type: Application
    Filed: July 1, 2021
    Publication date: October 28, 2021
    Inventors: Denise Zarins, Hanson Gifford, III, Mark E. Deem, Douglas Sutton, Howard R. Levin, Mark Gelfand
  • Publication number: 20210298826
    Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
    Type: Application
    Filed: June 14, 2021
    Publication date: September 30, 2021
    Inventors: Mark E. Deem, Hanson S. Gifford, III, Denise Zarins, Douglas Sutton, Erik Thai, Mark Gelfand, Howard R. Levin
  • Patent number: 11083572
    Abstract: A heart valve repair device, comprising an atrial-fixation member having an expandable mesh configured to have oval or circular shape in a deployed configuration, the atrial-fixation member defining a central lumen; and a baffle extending from a portion of the atrial-fixation member, the baffle having an anterior portion with a smooth, atraumatic surface configured to coapt with at least a portion of one or more native leaflets of a native heart valve, a posterior portion configured to engage and displace at least a portion of another native leaflet of the native heart valve, wherein the baffle extends radially inward from the atrial-fixation member into the central lumen to approximate a closed position of the displaced native leaflet.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: August 10, 2021
    Assignee: Half Moon Medical, Inc.
    Inventors: Matt McLean, Hanson S. Gifford, III, James I. Fann, Douglas Sutton