Abstract: A process for adding compliance to a blood vessel preferably includes forming a first puncture through a first wall segment of the blood vessel, forming a second puncture through a second wall segment of the blood vessel at a diametrically opposed location, deploying a first tissue anchor on an outside of the blood vessel in an area of the first puncture, deploying a second tissue anchor on the outside of the blood vessel in an area of the second puncture, and tensioning an elastic band coupled to the first tissue anchor and the second tissue anchor, thereby causing the elastic band to reshape the target segment of the blood vessel to a non-circular cross-sectional shape. The elastic band elongates and contracts during cardiac cycles for adding compliance to the blood vessel.

Abstract: This invention prevents the unwanted opening of a zipper. The invention comprises one or more grippers affixed to the zipper tape which engage the zipper pull tab and prevent movement of the zipper slider. The design and construction minimize shortcomings in other locks.

Abstract: In some examples, a medical implant includes a frame and a radiopaque marker. The radiopaque marker is coupled to the strut with a recessed surface portion of the radiopaque marker positioned in opposing relation to a first concave surface of a strut portion of the frame. In some examples, at least one strut of the frame has a bore, an eyelet, and a strut portion between the bore and the eyelet. The radiopaque marker is disposed within the bore and has an edge surface with a recessed surface portion positioned in opposing relation to a first surface of the strut portion. In some examples, a medical assembly includes a delivery apparatus, a frame, and a radiopaque marker.

Abstract: A method and device for advancing a guidewire past a calcified leaflet of a heart valve are described. A dual guidewire device includes a primary guidewire, a secondary guidewire, and a sheath. The primary guidewire is configured to advance past a heart valve while the secondary guidewire is configured to pull open the calcified leaflet of the heart valve while the primary guidewire advances past the heart valve. The catheter can contain both the primary guidewire and the secondary guidewire.

Abstract: A system for delivering a guidewire through a heart valve comprises a delivery catheter configured to pass through a blood flow pathway of a heart, an inner catheter having an inner lumen, a guidewire configured to pass through the inner lumen of the inner catheter, and a positioning device crimped onto an outer surface of the inner catheter. wherein. The delivery catheter is configured to receive the inner catheter, guidewire, and positioning device and is configured to prevent expansion of the positioning device. The positioning device is configured to expand upon removal from the delivery catheter.

Abstract: The disclosure is related to methods for testing and/or validating drill pipe and threaded and coupled connectors for use in subsea intervention system riser applications (open-water and through-riser). The methods are novel applications for testing and/or validating drill pipe and threaded and coupled connections that conform to Annex E of API 17G.

Abstract: A first technique for ameliorating bioactivity deterioration in fatty acid delivery includes retarding oxidation of fatty acids during manufacture, transportation, and storage of the fatty acid. A second technique for ameliorating bioactivity deterioration in fatty acid delivery includes enteric microencapsulation to avoid destruction of fatty acids in the stomach in favor of dissolving the fatty acids in the small intestines.

Abstract: A product comprising theanine, caffeine, and CBD is disclosed. Alternatives to the specific components are also described. A product comprising theanine, pyridoxine triacetate, and CBD is also disclosed. Alternatives to the specific components are also described. In an embodiment, an oral thin film strip delivery system includes a polymer, muco-adhesive, or other component that allows the product to dissolve in the mouth.

Abstract: A method comprises anchoring a first suture to a first papillary muscle, anchoring the first suture to a ventricle wall, and cinching the first suture to cause the first papillary muscle to move closer to the ventricle wall.

Abstract: Disclosed are cannabidiol (CBD) formulations with high CBD content for providing a variety of health benefits, and a system for the extraction and packaging thereof. Embodiments include a soothing formulation, an acne treatment formulation, and a sunburn treatment formulation. A method of treating discomfort susceptible to treatment with an anti-inflammatory substance delivered to a site of inflammation is also disclosed.

Abstract: A heart valve repair system includes an implantable device and a connector. The implantable device is configured to attach to at least two leaflets of a native heart valve of a patient and hold the at least two leaflets in a relatively fixed position. The connector is separate from the implantable device and includes first and second tissue anchors. The connector is configured to be attached to the at least two leaflets of the native valve when the at least two leaflets are held by the implantable device in the relatively fixed position. The implantable device is configured to be detached from the at least two leaflets and removed from the patient with the connector remaining attached to the at least two leaflets.

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve. Other embodiments are also described.

Abstract: Described herein are artificial valves that have a frame and leaflets that grow or expand with a patient. Upon placing the valve inside the patient, the valve expands as the annulus of the patient expands. The frame of the valve is configured to expand which in turn causes the leaflets to expand (e.g., to grow). The valve includes a thin undulating wire embedded inside the leaflets. As the annulus of the patient grows, the frame expands, and as the frame expands, the leaflets grow. The growth or expansion of the leaflets is configured so that the valve continues to operate properly (e.g., the leaflets continue to coapt) with expansion of the annulus. The change in size of the valve can be configured to accommodate changes in size of the annulus from an infant or child to an adult.

Abstract: A double heart valve anchoring system can include a first anchor having at least a portion configured to be secured within a first trans-septal opening in an interventricular septum, a tricuspid valve device coupled to the first anchor, and a mitral valve device coupled to the first anchor.

Abstract: Rooms, structures, vehicles, and other objects can be accurately diagrammed, often without performing a physical on-site inspection. Photographs of a room, structure, vehicle, or other object are uploaded to a computer having a processor. A base calibration measure is determined for a room, structure, vehicle, object, or component thereof, depicted in the photographs using at least one known dimension for items observable in the photographs. The base calibration measure is then used to determine dimensions of other areas, items, or objects depicted in such photographs, and to create at least one scale diagram of the subject matter of the photographs. Damages areas of the structure/vehicle/object can be assessed from the scale diagram. The scale diagram can then be used to calculate appropriate insurance payment amounts for damage claims.

Abstract: The disclosure is related to methods for testing and/or validating drill pipe and threaded and coupled connectors for use in subsea intervention system riser applications (open-water and through-riser). The methods are novel applications for testing and/or validating drill pipe and threaded and coupled connections that conform to Annex E of API 17G.

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. The clasps each have a fixed arm and a plurality of moveable arms each having a barbed portion. A plurality of hinge portions connect the moveable arms to the fixed arm.

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. The clasps have a fixed arm attached to the paddle and a moveable arm. The moveable arm has a barbed portion, a first eyelet, and a second eyelet. The hinge portion connects the fixed arm to the moveable arm. A first intermediate suture loop is attached to the first eyelet and a second intermediate suture loop is attached to the second eyelet. At least one actuation suture is attached to the first and second intermediate suture loops.

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the inner portion of the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. A cover wraps around at least a portion of the moveable arm of the clasp. At least one actuation suture is attached to the cover.

Abstract: An implantable prosthetic has a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp has a fixed arm attached to the paddle. The clasps also have a moveable arm having a barbed portion and an end that is rounded. A hinge portion connects the fixed arm to the moveable arm.