Patents by Inventor Douglas Trask

Douglas Trask has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting VEGF-C
    Publication number: 20070042986
    Abstract: The present invention provides RNA molecules (e.g., antisense, RNAi, or siRNA) specific for VEGF-C, and further provides methods of reducing expression of VEGF-C in cells (e.g., cancer cells).
    Type: Application
    Filed: October 24, 2006
    Publication date: February 22, 2007
    Applicant: University of Iowa Research Foundation
    Inventors: Douglas Trask, Jonathan Bock
  • Use of the sodium iodine symporter to effect uptake of iodine
    Publication number: 20060193832
    Abstract: The present invention relates to the use of gene therapy to introduce an iodine symporter into cell to increase iodine uptake therein. This approach has particular utility in the treatment of cancers that incapable of removing iodine. In addition, strategies are provided for reducing the export of sodium from cells to improve the efficacy of the iodine symporter gene therapy.
    Type: Application
    Filed: February 1, 2006
    Publication date: August 31, 2006
    Inventors: Frederick Domann, Andrew Gaut, Douglas Trask, Gang Niu, Kimberly Krager
  • Methods of inhibiting manganese-containing superoxide dismutase 2 (MnSOD)
    Publication number: 20060025369
    Abstract: The present invention provides RNA molecules (e.g., antisense, RNAi, or siRNA) specific for MnSOD, and further provides methods of reducing expression of MnSOD in cells (e.g., cancer cells).
    Type: Application
    Filed: August 1, 2005
    Publication date: February 2, 2006
    Inventors: Douglas Trask, Jonathan Bock
  • Methods of inhibiting COX-2
    Publication number: 20060025371
    Abstract: The present invention provides RNA molecules (e.g., antisense, RNAi, or siRNA) specific for COX-2, and further provides methods of reducing expression of COX-2 in cells (e.g., cancer cells).
    Type: Application
    Filed: August 1, 2005
    Publication date: February 2, 2006
    Inventors: Douglas Trask, Jonathan Bock
  • Methods of inhibiting VEGF-C
    Publication number: 20060025370
    Abstract: The present invention provides RNA molecules (e.g., antisense, RNAi, or siRNA) specific for VEGF-C, and further provides methods of reducing expression of VEGF-C in cells (e.g., cancer cells).
    Type: Application
    Filed: August 1, 2005
    Publication date: February 2, 2006
    Inventors: Douglas Trask, Jonathan Bock
  • Promotion of maturation of hematopoietic progenitor cells
    Patent number: 5154921
    Abstract: A method for promoting maturation of a hematopoietic precursor cell of an animal, which method includes the step of contacting the cell with a maturation-promoting amount of GRO, a polypeptide growth factor.
    Type: Grant
    Filed: July 13, 1990
    Date of Patent: October 13, 1992
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Ruth Sager, Douglas Trask, Phong Le