Patents by Inventor Douglas W. Harris

Douglas W. Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial methods and materials
    Publication number: 20030180821
    Abstract: The present invention provides methods of identifying agents that bind gene products critical for the survival of microbes, preferably Staphylococcus microbes, including agents that interfere with the expression of such gene products and agents that interfere with the function of such gene products.
    Type: Application
    Filed: May 2, 2003
    Publication date: September 25, 2003
    Applicant: PHARMACIA & UPJOHN COMPANY
    Inventors: Che-Shen C. Tomich, Cheryl L. Quinn, Staffan Arvidson, John E. Mott, Douglas W. Harris
  • Antimicrobial methods and materials
    Publication number: 20030087321
    Abstract: The present invention provides methods of identifying agents that bind gene products critical for the survival of microbes, preferably Staphylococcus microbes, including agents that interfere with the expression of such gene products and agents that interfere with the function of such gene products.
    Type: Application
    Filed: September 28, 2001
    Publication date: May 8, 2003
    Inventors: Che-Shen C. Tomich, Cheryl L. Quinn, Staffan Arvidson, John E. Mott, Douglas W. Harris
  • Antibody having binding specificity for human ouabain
    Patent number: 5844091
    Abstract: Methods for diagnosing pre-hypertension, hypertension, congestive cardiomyopathy, renal failure, salt-sensitivity and adenomas and endocrine cell hyperplasias are disclosed. Also disclosed are methods for monitoring hypertension therapy, congestive cardiomyopathy therapy, renal failure therapy and adenoma and endocrine cell hyperplasia therapy. These methods involve using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject. Additionally, methods for treating a hypertensive subject by inducing passive or active immunity to human ouabain in the subject are disclosed, along with an antibody having binding specificity for ouabain.
    Type: Grant
    Filed: June 25, 1993
    Date of Patent: December 1, 1998
    Assignee: University of Maryland, Baltimore
    Inventors: Mordecai P. Blaustein, John M. Hamlyn, Douglas W. Harris, James H. Ludens, William Rodney Mathews, Jed F. Fisher, Frederic Mandel, Donald W. DuCharme
  • Methods for treating hypertension
    Patent number: 5695756
    Abstract: Methods for diagnosing pre-hypertension, hypertension, congestive cardiomyopathy, renal failure, salt-sensitivity and adenomas and endocrine cell hyperplasias are disclosed. Also disclosed are methods for monitoring hypertension therapy, congestive cardiomyopathy therapy, renal failure therapy and adenoma and endocrine cell hyperplasia therapy. These methods involve using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject. Additionally, methods for treating a hypertensive subject by inducing passive or active immunity to human ouabain in the subject are disclosed, along with an antibody having binding specificity for ouabain.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 9, 1997
    Assignee: University of Maryland at Baltimore
    Inventors: Mordecai P. Blaustein, John M. Hamlyn, Douglas W. Harris, James H. Ludens, William Rodney Mathews, Jed F. Fisher, Frederic Mandel, Donald W. DuCharme
  • Immunoassay for detecting human ouabain
    Patent number: 5429928
    Abstract: Methods using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject are disclosed.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: July 4, 1995
    Assignee: University of Maryland at Baltimore
    Inventors: Mordecai P. Blaustein, John M. Hamlyn, Douglas W. Harris, James H. Ludens, William R. Mathews, Jed F. Fisher, Frederic Mandel, Donald W. DuCharme
  • Assay methods involving ouabain
    Patent number: 5164296
    Abstract: Methods for diagnosing pre-hypertension, hypertension, congestive cardiomyopathy, renal failure, salt-sensitivity and adenomas and endocrine cell hyperplasias are disclosed. Also disclosed are methods for monitoring hypertension therapy, congestive cardiomyopathy therapy, renal failure therapy and adenoma and endocrine call hyperplasia therapy. These methods involve using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject. Additionally, methods for treating a hypertensive subject by inducing passive or active immunity to human ouabain in the subject are disclosed, along with an antibody having binding specificity for ouabain.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: November 17, 1992
    Assignee: University of Maryland at Baltimore
    Inventors: Mordecai P. Blaustein, John M. Hamlyn, Douglas W. Harris, James H. Ludens, William R. Mathews, Jed F. Fisher, Frederic Mandel, Donald W. DuCharme