Patents by Inventor Douglas W. McMillin

Douglas W. McMillin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL CO-CULTURE SYSTEMS AND USES THEREOF
    Publication number: 20190011433
    Abstract: The invention provides a cell co-culture for the selective evaluation of the response of a cell of interest in the co-culture, and methods of using the co-culture. The cell co-culture and the methods are suitable for large-scale/high throughput screening for compounds useful for affecting at least one biological function or event of at least one cell type in the co-culture. The invention further provides kits for using the screening assays.
    Type: Application
    Filed: February 5, 2018
    Publication date: January 10, 2019
    Inventors: Constantine S. Mitsiades, Douglas W. McMillin, Joseph M. Negri, Nicholas Mitsiades, Kenneth C. Anderson
  • Cell Co-Culture Systems and Uses Thereof
    Publication number: 20130274142
    Abstract: The invention provides a cell co-culture for the selective evaluation of the response of a cell of interest in the co-culture, and methods of using the co-culture. The cell co-culture and the methods are suitable for large-scale/high throughput screening for compounds useful for affecting at least one biological function or event of at least one cell type in the co-culture. The invention further provides kits for using the screening assays.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 17, 2013
    Inventors: Constantine S. Mitsiades, Douglas W. McMillin, Joseph M. Negri, Nicholas Mitsiades, Kenneth C. Anderson
  • Use of reversine and analogs for treatment of cancer
    Patent number: 8466147
    Abstract: Herein is provided methods and compositions for treating cancer. In one embodiment, a method is provided for treating a patient suffering from cancer, the method comprising administering to the patient an effective amount of reversine, reversine analog or reversine containing agent. In another embodiment, compositions comprising reversine are provided. Such compositions may further comprise additional active agents and other additives. The compositions and methods provided herein are useful, for example, in the area of medicine.
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: June 18, 2013
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Kenneth C. Anderson, Nicholas Mitsiades, Joseph Negri, Douglas W. McMillin, Constantine S. Mitsiades
  • Cell Co-Culture Systems and Uses Thereof
    Publication number: 20100255999
    Abstract: The invention provides a cell co-culture for the selective evaluation of the response of a cell of interest in the co-culture, and methods of using the co-culture. The cell co-culture and the methods are suitable for large-scale/high throughput screening for compounds useful for affecting at least one biological function or event of at least one cell type in the co-culture. The invention further provides kits for using the screening assays.
    Type: Application
    Filed: February 1, 2008
    Publication date: October 7, 2010
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Constantine S. Mitsiades, Douglas W. McMillin, Joseph M. Negri, Nicholas Mitsiades, Kenneth C. Anderson
  • Use of Reversine and Analogs For Treatment of Cancer
    Publication number: 20100172893
    Abstract: Herein is provided methods and compositions for treating cancer. In one embodiment, a method is provided for treating a patient suffering from cancer, the method comprising administering to the patient an effective amount of reversine, reversine analog or reversine containing agent. In another embodiment, compositions comprising reversine are provided. Such compositions may further comprise additional active agents and other additives. The compositions and methods provided herein are useful, for example, in the area of medicine.
    Type: Application
    Filed: November 12, 2007
    Publication date: July 8, 2010
    Inventors: Kenneth C. Anderson, Nicholas Mitsiades, Joseph Negri, Douglas W. McMillin, Constantine S. Siades