Abstract: A physiologically stable fluorophore includes a terminal moiety including a terminal reactive site that reacts with a reactive group of a substrate; a stability linker covalently bonded to the terminal moiety; and a bridge moiety covalently bonded to the stability linker such that the stability linker is interposed through chemical bonds between the bridge moiety and the terminal moiety; and a fluorescent moiety covalently bonded to the bridge moiety of the redox moiety and including: an electron bandgap mediator that is covalently bonded to the bridge moiety; a coordinate center covalently bonded to the electron bandgap mediator and that forms a Zwitterionic member with an atom in the electron bandgap mediator; and a steric hinder bonded to the electron bandgap mediator to provide steric hindrance for protection of the coordinate center.

Abstract: A high-speed transmission circuit comprises, as part of a signal path, a connector pin disposed on a pad that comprises an unused pad region. The unused pad region is not considered part of the signal path but is part of a resonant sub-circuit. In various embodiments, by properly adjusting the dimensions of the pad region and other structures in the high-speed transmission circuit, resonant frequencies of the sub-circuit are shifted to a frequency range that is outside of the frequency range of interest in the signal path, thereby, reducing insertion loss and increasing signal integrity without compromising mechanical stability.

Abstract: An information handling system includes a first component including a transmitter for a high-speed serial data interface, and a second component including a receiver for the high-speed serial data interface. The receiver includes an equalization stage and a decision feedback equalization (DFE) stage. The equalization stage has an input to configure the equalization stage in one of a first low equalization state and a first high equalization state. The DFE stage has a plurality of tap inputs. The first component provides a plurality of training runs on the high-speed serial data interface.

Abstract: A modifiable jewelry system. The modifiable jewelry system may include a main jewelry body, wherein the main jewelry body may include a track along at least a portion of the main jewelry body and a securing component. The modifiable jewelry system may further include one or more attachable/detachable components, the one or more attachable/detachable components may include a decorative portion and a retaining body portion, wherein the retaining body portion may be configured to be received by the track of the main body, and wherein the received retaining body portion may be releasable retained within an internal portion of the track via the securing mechanism.

Abstract: An information handling system includes a first component including a transmitter for a high-speed serial data interface, and a second component including a receiver for the high-speed serial data interface. The receiver includes an equalization stage and a decision feedback equalization (DFE) stage. The equalization stage has an input to configure the equalization stage in one of a first low equalization state and a first high equalization state. The DFE stage has a plurality of tap inputs. The first component provides a plurality of training runs on the high-speed serial data interface.

Abstract: A modifiable jewelry system. The modifiable jewelry system may include a main jewelry body, wherein the main jewelry body may include a track along at least a portion of the main jewelry body and a securing component. The modifiable jewelry system may further include one or more attachable/detachable components, the one or more attachable/detachable components may include a decorative portion and a retaining body portion, wherein the retaining body portion may be configured to be received by the track of the main body, and wherein the received retaining body portion may be releasable retained within an internal portion of the track via the securing mechanism.

Abstract: A high-speed transmission circuit comprises, as part of a signal path, a connector pin disposed on a pad that comprises an unused pad region. The unused pad region is not considered part of the signal path but is part of a resonant sub-circuit. In various embodiments, by properly adjusting the dimensions of the pad region and other structures in the high-speed transmission circuit, resonant frequencies of the sub-circuit are shifted to a frequency range that is outside of the frequency range of interest in the signal path, thereby, reducing insertion loss and increasing signal integrity without compromising mechanical stability.

Abstract: A microfluidic device for mitochondria analysis includes an inlet coupled to a first access channel, an outlet coupled to a second access channel, and a plurality of trapping channels fluidically coupled at one end to the first access channel and fluidically coupled at an opposing end to the second access channel, each trapping channel has a cross-sectional dimension about 2 ?m in one direction and a cross-sectional dimension between about 0.45 and about 0.75 ?m in a second direction.

Abstract: A microfluidic device for mitochondria analysis includes an inlet coupled to a first access channel, an outlet coupled to a second access channel, and a plurality of trapping channels fluidically coupled at one end to the first access channel and fluidically coupled at an opposing end to the second access channel, each trapping channel comprises a cross-sectional dimension about 2 ?m in one direction and a cross-sectional dimension between about 0.45 and about 0.75 ?m in a second direction.

Abstract: A method, for determining sufficiency of a given set of portions included within a storage system (SS) to accommodate one or more flows of data anticipated as flowing therethrough, may include: configuring the given set to include at least one of following portions, a given stable of one or more providers of data-storage (PDSs), and an SS-infrastructure; identifying components within members of the given set as queuing centers according to the one or more flows, respectively; estimating one or more capacity values, based upon the one or more flows, that will be demanded of the components, respectively; and determining whether the estimated one or more capacity values are acceptable in a context of corresponding capacity values attributed to the components, respectively.

Abstract: A method for monitoring the activity of a tape drive system having one or more electro-mechanical components that receive electrical current from a power supply. The method includes sampling an actual current supplied to an electro-mechanical component of a tape drive system from a power supply during an activity; reading a theoretical current for said activity from a memory; calculating a statistical value for said actual current and said theoretical current; comparing said statistical value to at least one threshold value; and outputting information to at least one of a user, another system, and another process based on said comparison of said statistical value to said at least one threshold value.

Abstract: A system for monitoring an activity of a tape drive system having one or more electro-mechanical components, said electro-mechanical components receiving electrical current from a power supply. The system comprises a mechanism for sampling an actual current supplied to said electro-mechanical component from said power supply during said activity; a mechanism for reading a theoretical current for said activity; a mechanism for calculating a statistical value for said actual current and said theoretical current; a mechanism for comparing said statistical value to at least one threshold value; and a mechanism for outputting information to at least one of a user, another system, and another process based on said comparison of said statistical value to said at least one threshold value.

Abstract: An apparatus, system, and method are provided for authorized remote access to a target system. The apparatus, system, and method include a security module and an authorization module that cooperate to authenticate a remote user using three passwords. The apparatus, system, and method selectively generate an encrypted key in response to a first password. The authorization module decrypts the encrypted key and determines a third password in response to authenticating a second password and identifying a remote user within an authorized user list. The third password is then used to gain secure, traceable, and in certain embodiments, restricted remote access to a target system.

Abstract: A method and system for monitoring the activity of a system of one or more electro-mechanical components that receive electrical current from a power supply. The method and system samples an actual current supplied to the electro-mechanical component from the power supply. Next, the method and system reads a theoretical current for the activity of the system. A statistical value is computed from comparing the actual current and the theoretical current. This statistical value is compared to upper and lower threshold values. Depending upon this comparison, the system issues various output messages. Further, if this comparison indicates that one of the electro-mechanical components is failing, the method and system will shut that component down.

Abstract: This invention provides a library of genes involved in mitochondrial biology, arrays containing probes for genes involved in mitochondrial biology, methods for making such arrays, and methods of using such arrays. Genes and probe sequences involved in mitochondrial biology in humans and mice are provided. The arrays of this invention are useful for determining mitochondrial biology gene expression profiles. Mitochondrial biology gene expression profiles are useful for determining expression profiles diagnostic of physiological conditions; diagnosing physiological conditions; identifying biochemical pathways, genes, and mutations involved in physiological conditions; identify therapeutic agents useful for preventing and/or treating such physiological conditions; evaluating and/or monitoring the efficacy of such therapies, and creating and identifying animal models of human physiologic conditions.

Abstract: This invention provides human mtDNA polymorphisms that are diagnostic of all the major human haplogroups and methods of diagnosing those haplogroups and selected subhaplogroups. This invention also provides methods for identifying evolutionarily significant mitochondrial DNA genes, nucleotide alleles, and amino acid alleles. Evolutionarily significant genes and alleles are identified using one or two populations of a single species. The process of identifying evolutionarily significant nucleotide alleles involves identifying evolutionarily significant genes and then evolutionarily significant nucleotide alleles in those genes, and identifying evolutionarily significant amino acid alleles involves identifying amino acids encoded by all nonsynonymous alleles. Synonymous codings of the nucleotide alleles encoding evolutionarily significant amino acid alleles of this invention are equivalent to the evolutionarily significant amino acid alleles disclosed herein and are included within the scope of this invention.

Abstract: Described are methods for inactivating adenine nucleotide transporter proteins in specific tissues of a transgenic nonhuman animal using a conditional knockin/knockout technology such as the Cre-LoxP, Flip-FLP recombinase, or Tet-on/off technologies. Specifically, the Ant2 gene is functionally inactivated in a mouse in liver, with or without the concurrent inactivation of the Ant1 gene. The result is an animal in which the Ant2 gene and accompanying ANT2 protein is absent in one or more tissues, either in the presence or absence of the Ant1 gene and accompanying ANT1 protein. The resulting animals, cells, mitochondria, and subcelluar fractions such as the mitochondrial permeability transition pore can then be used to identify agents that affect animal and/or subcellular function via a direct or indirect interaction with the ANT2 protein and/or its Ant2 gene.

Abstract: A method and system for monitoring the activity of a system of one or more electromechanical components that receive electrical current from a power supply. The method and system samples an actual current supplied to the electromechanical component from the power supply. Next, the method and system reads a theoretical current for the activity of the system. A statistical value is computed from comparing the actual current and the theoretical current. This statistical value is compared to upper and lower threshold values. Depending upon this comparison, the system issues various output messages. Further, if this comparison indicates that one of the electromechanical components is failing, the method and system will shut that component down.

Abstract: A computerized test preparation system and methods are disclosed which assist an examinee to increase his learning and improve his performance on standardized academic or applied aptitude and achievement exams. Performance feedback information is provided to a user, including conventional information such as number of items correct and time elapsed, pinpoints substantive areas of a particular exam in which the user is either weak or strong, and offers diagnoses of, and remediation tailored to, a user's personal difficulties. By assessing a user's responses to given exam questions, through various distractor error patterns manifested in the incorrect answers to multiple-choice questions, or through coded categories of responses in the case of user responses to constrained open-ended items, a preliminary diagnosis of a user's deficits in knowledge and/or test taking skill is made. This preliminary diagnosis is subsequently refined utilizing additional examination questions.