Patents by Inventor Douglas Wilmore

Douglas Wilmore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating catabolic, gut-associated pathological processes and impaired host defenses
    Patent number: 5763485
    Abstract: The invention relates to a method for treating catabolic, gut-associated pathological processes including intestinal mucosal and pancreatic atrophy and enhanced gut permeability, impairment of host defenses and compromised immune function, and for promoting recovery from bone marrow transplantation in an animal, which comprises administering to an animal a therapeutically effective amount of glutamine or an analogue thereof.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: June 9, 1998
    Assignee: Brigham and Women's Hospital
    Inventors: Robert J. Smith, Douglas Wilmore
  • Method of treating pancreatic atrophy
    Patent number: 5684045
    Abstract: The invention relates to a method for treating catabolic, gut-associated pathological processes including intestinal mucosal and pancreatic atrophy and enhanced gut permeability, impairment of host defenses and compromised immune function, and for promoting recovery from bone marrow transplantation in an animal, which comprises administering to an animal a therapeutically effective amount of glutamine or an analogue thereof.
    Type: Grant
    Filed: May 7, 1996
    Date of Patent: November 4, 1997
    Assignee: Brigham and Women's Hospital
    Inventors: Robert J. Smith, Douglas Wilmore
  • Method of treating catabolic, gut-associated pathological processes and impaired host defenses
    Patent number: 5607975
    Abstract: The invention relates to a method for treating catabolic, gut-associated pathological processes including intestinal mucosal and pancreatic atrophy and enhanced gut permeability, impairment of host defenses and compromised immune function, and for promoting recovery from bone marrow transplantation in an animal, which comprises administering to an animal a therapeutically effective amount of glutamine or an analogue thereof.
    Type: Grant
    Filed: May 7, 1996
    Date of Patent: March 4, 1997
    Assignee: Brigham and Women's Hospital
    Inventors: Robert J. Smith, Douglas Wilmore
  • Use of glutamine to reduce rate of pathogenic microorganism infection
    Patent number: 5397803
    Abstract: The invention relates to a method for treating catabolic, gut-associated pathological processes including intestinal mucosal and pancreatic atrophy and enhanced gut permeability, impairment of host defenses and compromised immune function, and for promoting recovery from bone marrow transplantation in an animal, which comprises administering to an animal a therapeutically effective amount of glutamine or an analogue thereof.
    Type: Grant
    Filed: April 26, 1993
    Date of Patent: March 14, 1995
    Assignee: Brigham and Women's Hospital
    Inventors: Robert J. Smith, Douglas Wilmore
  • Intravenous solution that diminishes body protein loss
    Patent number: 5292722
    Abstract: The present invention provides compositions and methods of decreasing the nitrogen loss in a mammal which is normally associated with the administration of isocaloric solutions. Specifically, the present invention provides compositions comprising from about 4% to 10% dextrose and from about 1/2% to 2% glutamine. Such compositions, when administered to a mammal, reduces dehydration and nitrogen loss to approximately 25% of that found when no solution is administered.
    Type: Grant
    Filed: November 6, 1992
    Date of Patent: March 8, 1994
    Assignee: Brigham and Women's Hospital
    Inventor: Douglas Wilmore
  • Method for enhancing gut absorption
    Patent number: 5288703
    Abstract: The present invention provides a method for enhancing the gut absorption in a mammal. Specifically, gut absorption in a mammal can be enhanced by the administration of glutamine, or glutamine equivalent, in combination with one or more agents, said agents selected from the group consisting of growth hormone (GH), an agent capable of enhancing endogenous GH production, insulin like growth factor 1 (IGF-1), or an agent capable of enhancing endogenous IGF-1 production.
    Type: Grant
    Filed: October 7, 1992
    Date of Patent: February 22, 1994
    Assignee: Brigham and Women's Hospital
    Inventor: Douglas Wilmore