Patents by Inventor Douwe Rosenberg

Douwe Rosenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sterile composition comprising a chelate complex for magnetic resonance imaging
    Patent number: 5648063
    Abstract: A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more central ion or ions of an element with an atomic number of 21 to 29, 42, 44 or 57 to 83 and, optionally, one or more physiologically biocompatible cation or cations of an inorganic and/or organic base or amino acid, optionally, with additives customary in galenic formulations, dissolved or suspended in an aqueous medium.
    Type: Grant
    Filed: August 4, 1993
    Date of Patent: July 15, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann, Ulrich Speck, Wolfgang Mutzel, Georg-Alexander Hoyer, Heinrich Pfeiffer, deceased, Franz-Josef Renneke
  • Diagnostic media
    Patent number: 5595725
    Abstract: A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more central ion or ions of an element with an atomic number of 21 to 29, 42, 44 or 57 to 83 and, optionally, one or more physiologically biocompatible cation or cations of an inorganic and/or organic base or amino acid, optionally, with additives customary in galenic formulations, dissolved or suspended in an aqueous medium.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: January 21, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann, Ulrich Speck, Wolfgang M utzel, Georg-Alexander Hoyer, Heinrich Pfeiffer, deceased, Franz-Josef Renneke
  • Method of enhancing paramagnetism in chelates for MRI
    Patent number: 5560903
    Abstract: A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more central ion or ions of an element with an atomic number of 21 to 29, 42, 44 or 57 to 83 and, optionally, one or more physiologically biocompatible cation or cations of an inorganic and/or organic base or amino acid, optionally, with additives customary in galenic formulations, dissolved or suspended in an aqueous medium.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 1, 1996
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann, Ulrich Speck, Wolfgang Mutzel, Georg-Alexander Hoyer, Heinrich Pfeiffer, Franz-Josef Renneke
  • Gadolinium chelates for magnetic resonance imaging
    Patent number: 5362475
    Abstract: A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more Gadolinium ions and, optionally, one or more physiologically biocompatible cation or cations of an inorganic and/or organic base or amino acid, optionally, with additives customary in galenic formulations, dissolved or suspended in an aqueous medium.
    Type: Grant
    Filed: July 10, 1992
    Date of Patent: November 8, 1994
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann, Ulrich Speck, Wolfgang Mutzel, Georg-Alexander Hoyer, Heinrich Pfeiffer, deceased, Franz-Josef Renneke
  • Method of enhancing NMR imaging using chelated paramagnetic ions bound to biomolecules
    Patent number: 5021236
    Abstract: Agents useful for influencing the relaxation times in NMR diagnostics, contain at least one paramagnetic, physiologically compatible complex salt comprising a chelate from an open-chain or cyclic complex-forming compound containing organic nitrogen, phosphorus, oxygen and/or sulfur, and a complexed ion of the lanthanide elements of atomic number 57-70 or of the transition metals of atomic numbers 21-29, 42 and 44, and, optionally, an inorganic or organic base or acid, wherein said chelate complex is bound to a biomolecule.
    Type: Grant
    Filed: March 2, 1987
    Date of Patent: June 4, 1991
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann, Ulrich Speck, Wolfgang Mutzel, Georg-Alexander Hoyer, Heinrich Pfeiffer, deceased
  • Method to enhance NMR imaging using chelated paramagnetic ions
    Patent number: 4963344
    Abstract: Agents useful for influencing the relaxation times in NMR diagnostics, contain at least one paramagnetic, physiologically compatible complex salt comprising a chelate from an open-chain or cyclic complex-forming compound containing organic nitrogen, phosphorus, oxygen and/or sulfur, and a complexed ion of the lanthanide elements of atomic number 57-70 or of the transition metals of atomic numbers 21-29, 42 and 44, and, optionally, an inorganic or organic base or acid.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: October 16, 1990
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann, Ulrich Speck, Wolfgang Mutzel, Georg-Alexander Hayden, Heinrich Pfeiffer
  • Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
    Patent number: 4957939
    Abstract: Pharmaceutical compositions comprising gadolinium chelates are useful for enhancing NMR images.
    Type: Grant
    Filed: June 20, 1986
    Date of Patent: September 18, 1990
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann
  • Diagnostic media
    Patent number: 4647447
    Abstract: A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more central ion or ions of an element with an atomic number of 21 to 29, 42, 44 or 57 to 83 and, optionally, one or more physiologically biocompatible cation or cations of an inorganic and/or organic base or amino acid, optionally, with additives customary in galenic formulations, dissolved or suspended in an aqueous medium.
    Type: Grant
    Filed: January 23, 1984
    Date of Patent: March 3, 1987
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Douwe Rosenberg, Hanns-Joachim Weinmann