Patents by Inventor Dragos Vizitiu

Dragos Vizitiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process methods for phosphatidylinositol 3-kinase inhibitors
    Patent number: 10954199
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: March 23, 2021
    Assignee: Gilead Sciences, Inc.
    Inventors: Stacy Bremner, Jerry Evarts, Keiko Sujino, Duong Tran, Dragos Vizitiu
  • PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
    Publication number: 20200102277
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Application
    Filed: August 6, 2019
    Publication date: April 2, 2020
    Inventors: Stacy BREMNER, Jerry EVARTS, Keiko SUJINO, Duong TRAN, Dragos VIZITIU
  • Process methods for phosphatidylinositol 3-kinase inhibitors
    Patent number: 10414737
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: September 17, 2019
    Assignee: Gilead Sciences, Inc.
    Inventors: Stacy Bremner, Jerry B. Evarts, Keiko Sujino, Duong Tran, Dragos Vizitiu
  • Polymorph of Syk inhibitors
    Patent number: 10266539
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, are provided. The bis-mesylate salt may also be depicted as a compound of Formula IA: Provided herein are also compositions thereof, methods for their preparation and methods for such polymorphs.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: April 23, 2019
    Assignee: Gilead Connecticut, Inc.
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Michael Laird Hurrey, Dimitrios Stefanidis, Dragos Vizitiu
  • PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
    Publication number: 20190031626
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Application
    Filed: July 2, 2018
    Publication date: January 31, 2019
    Inventors: Stacy BREMNER, Jerry B. EVARTS, Keiko SUJINO, Duong TRAN, Dragos VIZITIU
  • Process for preparing phosphatidylinositol 3-kinase inhibitors and intermediates thereof
    Patent number: 10059677
    Abstract: A process for the synthesis of benzoxazinone containing compounds which may be useful precursors for synthesizing compounds for the treatment of cancer, is hereby disclosed.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: August 28, 2018
    Assignee: Gilead Calistoga LLC
    Inventors: Stacy Bremner, Jerry Evarts, Keiko Sujino, Duong Tran, Dragos Vizitiu
  • Process methods for phosphatidylinositol 3-kinase inhibitors
    Patent number: 10047060
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: August 14, 2018
    Assignee: Gilead Calistoga LLC
    Inventors: Stacy Bremner, Jerry Evarts, Keiko Sujino, Duong Tran, Dragos Vizitiu
  • PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
    Publication number: 20180162826
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Application
    Filed: November 17, 2017
    Publication date: June 14, 2018
    Inventors: Stacy BREMNER, Jerry EVARTS, Keiko SUJINO, Duong TRAN, Dragos VIZITIU
  • POLYMORPH OF SYK INHIBITORS
    Publication number: 20180099971
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, are provided. The bis-mesylate salt may also be depicted as a compound of Formula IA: Provided herein are also compositions thereof, methods for their preparation and methods for such polymorphs.
    Type: Application
    Filed: October 19, 2017
    Publication date: April 12, 2018
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Michael Laird Hurrey, Dimitrios Stefanidis, Dragos Vizitiu
  • POLYMORPH OF SYK INHIBITORS
    Publication number: 20170217967
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, are provided. The bis-mesylate salt may also be depicted as a compound of Formula IA: Provided herein are also compositions thereof, methods for their preparation and methods for such polymorphs.
    Type: Application
    Filed: April 11, 2017
    Publication date: August 3, 2017
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Michael Laird Hurrey, Dimitrios Stefanidis, Dragos Vizitiu
  • Polymorph of Syk inhibitors
    Patent number: 9657023
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, are provided. The bis-mesylate salt may also be depicted as a compound of Formula IA: Provided herein are also compositions thereof, methods for their preparation and methods for such polymorphs.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: May 23, 2017
    Assignee: Gilead Connecticut, Inc.
    Inventors: Tim G. Elford, Peter Chee-Chu Fung, Michael Laird Hurrey, Dimitrios Stefanidis, Dragos Vizitiu
  • PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
    Publication number: 20170107187
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Application
    Filed: December 28, 2016
    Publication date: April 20, 2017
    Inventors: Stacy BREMNER, Jerry EVARTS, Keiko SUJINO, Duong TRAN, Dragos VIZITIU
  • Process methods for phosphatidylinositol 3-kinase inhibitors
    Patent number: 9567337
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: February 14, 2017
    Inventors: Stacy Bremner, Jerry Evarts, Keiko Sujino, Duong Tran, Dragos Vizitiu
  • POLYMORPH OF SYK INHIBITORS
    Publication number: 20160168155
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula (I): or a hydrate thereof, are provided. The bis-mesylate salt may also be depicted as a compound of Formula (IA): Provided herein are also compositions thereof, methods for their preparation and methods for such polymorphs.
    Type: Application
    Filed: July 29, 2014
    Publication date: June 16, 2016
    Inventors: Peter Chee-Chu Fung, Dimitrios Stefanidis, Dragos Vizitiu, Tim G. Elford, Michael Laird Hurrey
  • PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINDASE INHIBITORS
    Publication number: 20150175605
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Application
    Filed: December 18, 2014
    Publication date: June 25, 2015
    Inventors: Stacy Bremner, Jerry Evarts, Keiko Sujino, Duong Tran, Dragos Vizitiu
  • POLYMORPH OF SYK INHIBITORS
    Publication number: 20150038505
    Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, are provided. The bis-mesylate salt may also be depicted as a compound of Formula IA: Provided herein are also compositions thereof, methods for their preparation and methods for such polymorphs.
    Type: Application
    Filed: July 29, 2014
    Publication date: February 5, 2015
    Inventors: Tim G. ELFORD, Peter Chee-Chu FUNG, Michael Laird HURREY, Dimitrios STEFANIDIS, Dragos VIZITIU
  • Enantiomeric resolution of 2-substituted 4-substituted 1,3-oxathiolanes nucleosides
    Patent number: 7501514
    Abstract: Single enantionmers of compounds of formula (B), in either the cis or trans configuration, wherein R1 and R2 are as defined herein, can be separated from enantiomeric mixtures thereof by reacting the compound with an acid to produce a conglomerate salt that has the following characteristics: the IR spectrum of the salt of the racemic compound, a 1:1 mixture of (?) and (+) crystals, is identical to that of the each of the single enantiomer, and the salt of the racemic compound has a melting point lower that that of either single enantiomer. The conglomerate salt is then separated by preferential crystallization.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: March 10, 2009
    Assignee: Shire Biochem, Inc.
    Inventors: Dragos Vizitiu, Ioana R. Simion, legal representative, Jean-Eric Lacoste, Dan Simion