Patents by Inventor Dragutin Knezic

Dragutin Knezic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Co-crystals and pharmaceutical formulations comprising the same
    Patent number: 8541025
    Abstract: An immediate release formulation of an active ingredient.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: September 24, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Eleni Dokou, Rahela Gasparac, Dragutin Knezic, Billie J. Kline, Valdas Jurkauskas
  • CO-CRYSTALS AND PHARMACEUTICAL FORMULATIONS COMPRISING THE SAME
    Publication number: 20130072440
    Abstract: The pharmaceutical composition including a co-crystal. The co-crystal includes a) a co-former; and b) an active pharmaceutical ingredient (API) with solubility in water is less than one part by weight of the API in ten parts by weight of water. Furthermore, the formulation includes a polymer, and a weight ratio of the co-crystal to the polymer is about 0.5:99.5 to about 99.5:0.5. The kinetic solubility of the co-crystal after being in contact with an environment of use is at a therapeutically acceptable level for a prolonged period of time.
    Type: Application
    Filed: September 10, 2012
    Publication date: March 21, 2013
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Eleni Dokou, Dragutin Knezic
  • CO-CRYSTALS AND PHARMACEUTICAL FORMULATIONS COMPRISING THE SAME
    Publication number: 20110236478
    Abstract: An immediate release formulation of an active ingredient.
    Type: Application
    Filed: February 24, 2011
    Publication date: September 29, 2011
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Eleni Dokou, Rahela Gasparac, Dragutin Knezic, Billie J. Kline, Valdas Jurkauskas