Abstract: Described herein are catechin multimers, and particularly substituted catechin multimers, and their use as carrier moieties for the delivery of nucleophilic and cationic bioactive therapeutic agents to target sites in vivo. For example, substituted catechin multimers of the present invention may be administered alone, for the treatment of stenotic vascular diseases and disorders, such as atherosclerosis (also known as arteriosclerosis) and coronary heart disease (also known as coronary artery disease and ischemic heart disease).

Abstract: Described herein are novel, therapeutic pharmaceutical and nutraceutical compositions useful for treating stenotic vascular diseases and disorders, such as atherosclerosis and coronary artery disease, and reducing formation of plaque on vascular walls and methods of using same. More particularly, the present invention relates to dietary supplements comprised of gallic acid, or a derivative thereof, in combination with limonene, or a derivative thereof, formulated so as to effectively reduce plaque formation, reversing plaque deposition and degenerative changes in the arterial walls, and/or removal of existing plaques from the vascular walls of animals, preferably humans. The dietary supplements may be formulated “neat” (e.g., without additives) or with additives such as pharmaceutical carriers, diluents, buffers, adjuvants, excipients, surfactants, and stabilizers.

Abstract: A new and distinct variety of grapevine producing early maturing black seedless table grapes.

Abstract: A new and distinct variety of grapevine producing early maturing black seedless table quality grapes which are firm and large with no splitting.