Abstract: This disclosure provides methods for producing T cells with shortened ex vivo manufacturing time. In particular, this disclosure involves the production of T cells from hematopoietic stem cells with the proviso that the process does not involve subsequent in vitro steps of activation and/or expansion of the T cells.

Abstract: The disclosure provides a method of generating modified T cells from engineered stem cells for use in an autologous or allogeneic setting for engineered immunotherapy. The knockout of endogenous TCR or HLA expression allows for engineering of modified pluripotent stem cells that reduce or eliminate the risk of Graft versus Host Disease (GVHD), provide resistance to elimination by a recipient's T cells and NK cells, and allow for controllable T cell activity. Thus, this method allows the development of T cells with reduced immune reactivity.

Abstract: A protective garment configured to facilitate easy donning of the garment is described. The sleeves and legs are shorted and held in a donning configuration by releaseably affixing at least a portion of upper and lower segments of the interior surface of each limb. This allows the garment to be handled and donned by the wearer, without the wearer touching an exterior surface of the garment. A method of preparing a protective garment for donning and a method of donning such a garment is also disclosed.

Abstract: Methods and systems for calibrating an inductor-inductor-capacitor (LLC) resonant converter are provided herein. The method includes calculating input voltage mathematically as a function of at least one of an output voltage, a load current, and tolerances of components of the LLC resonant converter and operating the LLC resonant converter in an open loop mode at a nominal resonant frequency. The method also includes measuring output voltage of the LLC resonant converter and comparing the measured output voltage to the calculated input voltage.

Abstract: A power interruption circuit for use in a power distribution module is provided. The power interruption circuit is configured to provide power to a load and includes a shunt resistor, a plurality of switches, and microprocessor. The microprocessor is configured to determine a digitized value of a current flowing through the shunt resistor, determine a digitized value of an output voltage of the power interruption circuit, calculate, from the digitized current value and the digitized output voltage value, a power provided by the power interruption circuit to the load, compare the calculated power to a threshold power level, and control the plurality of switches based on the comparison.

Abstract: A protective garment configured to facilitate easy donning of the garment is described. The sleeves and legs are shorted and held in a donning configuration by releaseably affixing at least a portion of upper and lower segments of the interior surface of each limb. This allows the garment to be handled and donned by the wearer, without the wearer touching an exterior surface of the garment. A method of preparing a protective garment for donning and a method of donning such a garment is also disclosed.

Abstract: A protective garment configured to facilitate easy donning of the garment is described. The sleeves and legs are shorted and held in a donning configuration by releaseably affixing at least a portion of upper and lower segments of the interior surface of each limb. This allows the garment to be handled and donned by the wearer, without the wearer touching an exterior surface of the garment. A method of preparing a protective garment for donning and a method of donning such a garment is also disclosed.

Abstract: Methods and systems for calibrating an inductor-inductor-capacitor (LLC) resonant converter are provided herein. The method includes calculating input voltage mathematically as a function of at least one of an output voltage, a load current, and tolerances of components of the LLC resonant converter and operating the LLC resonant converter in an open loop mode at a nominal resonant frequency. The method also includes measuring output voltage of the LLC resonant converter and comparing the measured output voltage to the calculated input voltage.

Abstract: A power interruption circuit for use in a power distribution module is provided. The power interruption circuit is configured to provide power to a load and includes a shunt resistor, a plurality of switches, and microprocessor. The microprocessor is configured to determine a digitized value of a current flowing through the shunt resistor, determine a digitized value of an output voltage of the power interruption circuit, calculate, from the digitized current value and the digitized output voltage value, a power provided by the power interruption circuit to the load, compare the calculated power to a threshold power level, and control the plurality of switches based on the comparison.

Abstract: A vacuum packaged product and method for reducing tensile strength loss associated with sterilization of polyolefin-based products by gamma radiation, and reducing odors commonly produced by such sterilization.

Abstract: A vacuum packaged product and method for reducing tensile strength loss associated with sterilization of polyolefin-based products by gamma radiation, and reducing odors commonly produced by such sterilization.

Abstract: An interactive television (ITV) system transmitting ITV content created and received by different ITV platforms via a single ITV stream. The system provides universal time codes which are embedded into the ITV stream. Each time code is associated with a program identifier which uniquely identifies a particular program. An ITV receiver receives the ITV stream and compares the program identifier and time code with a program held in the receiver's memory. When a match is found, an interactive event indicated by the program is executed. The program may be loaded into the receiver's memory using a back channel.

Abstract: A protective garment with an interior surface indicator to facilitate proper donning of the garment is described. The garment includes at least one indicia on the central portion of the interior surface of the garment to communicate to the wearer which is the interior surface of the garment. This allows the garment to be handled and donned by the wearer, without the wearer touching an exterior surface of the garment. A method of preparing a protective garment for donning is also disclosed.

Abstract: A vacuum packaged product and method for reducing tensile strength loss associated with sterilization of polyolefin-based products by gamma radiation, and reducing odors commonly produced by such sterilization.

Abstract: A method and apparatus for delivering interactive television (ITV) data by using the same TV scan line that also carries closed caption data. The ITV data is inserted into the scan line with CC data by detecting a gap associated with a first CC data unit. If the gap is large enough to contain all of the group of ITV data units then electronically insert the entire group of ITV data units into the gap. If the gap is not large enough to contain the entire group of ITV data units, insert a subset of the entire group of the ITV data units into the gap and continue to the gaps associated with successive CC data units, inserting subsets of the ITV data into subsequent gaps until the entire ITV message has been inserted into the gaps between CC data units.

Abstract: A protective garment configured to facilitate easy donning of the garment is described. The sleeves and legs are shorted and held in a donning configuration by releaseably affixing at least a portion of upper and lower segments of the interior surface of each limb. This allows the garment to be handled and donned by the wearer, without the wearer touching an exterior surface of the garment. A method of preparing a protective garment for donning and a method of donning such a garment is also disclosed.

Abstract: A system and method for efficiently and quickly handling content and transaction requests from various users at respective end terminals. According to embodiments of the invention, plural servers are provided at the web site to randomly receive requests from users over a communications network, such as the Internet. Each server contains a memory, such as a cache or disk storage process, that contains a copy of all data contained on every other server. When a request comes in to one of the servers, in addition to processing the request, that server broadcasts data corresponding to the request to the other servers, which are programmed to store the same request data in their respective local memories. Such broadcasts may be preferably carried out over a back-end, private network.

Abstract: A system and method are disclosed for preloading interactive content before it is to be displayed, thereby avoiding any unwanted delays due to download times. According to the invention, ITV data is embedded into the signal at some predetermined time before the corresponding segment will be broadcast. The ITV data is received by the ITV receiver, which then accesses an interactive site (web site or other server) and makes a request for the interactive content. The server determines the location of the content, and the content is then retrieved and transmitted to the ITV receiver. At the appropriate time (e.g., when the corresponding TV segment is being displayed), the content is displayed on the user's display, thereby reliably providing simultaneous display of the segment and corresponding interactive content.

Abstract: A command protocol enables an applications programming interface (API) between a first interactive television (ITV) equipment and a second ITV equipment for seamless communication between the two. An API command generator receives data from the first ITV equipment in a first format. The data may be, for example, a list of ITV events to be encoded into a television program. The command generator converts data into a second format according to the API and transmits the data in the second format to the second ITV equipment. The second ITV equipment may be, for example, an ITV data encoder encoding the list of ITV events transmitted by the first ITV equipment.

Abstract: An interactive television (ITV) system transmitting ITV content created and received by different ITV platforms via a single ITV stream. The system provides universal time codes which are embedded into the ITV stream. Each time code is associated with a program identifier which uniquely identifies a particular program. An ITV receiver receives the ITV stream and compares the program identifier and time code with a program held in the receiver's memory. When a match is found, an interactive event indicated by the program is executed. The program may be loaded into the receiver's memory using a back channel.