Patents by Inventor Drazen Ostovic

Drazen Ostovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240285536
    Abstract: Formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Application
    Filed: April 22, 2024
    Publication date: August 29, 2024
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Patent number: 11992470
    Abstract: The invention provides stable, aqueous capsaicin injectable formulations, a unit dose containing such injectable formulations, medical kits, and methods for using such injectable formulations and unit doses to treat patients suffering from pain, such as osteoarthritic knee pain. The stable, aqueous capsaicin injectable formulations may contain, for example, capsaicin, a solubilizing agent (e.g., a polyethylene glycol ester of a (C15-C25) hydroxyalkanoic acid), an antioxidant, and water.
    Type: Grant
    Filed: March 22, 2022
    Date of Patent: May 28, 2024
    Assignee: Centrexion Therapeutics Corporation
    Inventors: Drazen Ostovic, Gary Fred Musso
  • Patent number: 11964054
    Abstract: Formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Grant
    Filed: February 6, 2023
    Date of Patent: April 23, 2024
    Assignee: Iterion Therapeutics, Inc.
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Publication number: 20240074977
    Abstract: Lyophilized formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Application
    Filed: October 24, 2023
    Publication date: March 7, 2024
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Publication number: 20230365564
    Abstract: Cocrystals of an adenosine A2B receptor antagonist, 3-ethyl-1-propyl-8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-3,7-dihydro-1H-purine-2,6-dione, methods of preparing the cocrystals, pharmaceutical compositions of the cocrystals, and uses of the cocrystals are disclosed.
    Type: Application
    Filed: September 3, 2021
    Publication date: November 16, 2023
    Inventors: Jiwen LIU, Drazen OSTOVIC, Sami KARABORNI
  • Patent number: 11793759
    Abstract: Lyophilized formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: October 24, 2023
    Assignee: ITERION THERAPEUTICS, INC.
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Publication number: 20230190659
    Abstract: Formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Application
    Filed: February 6, 2023
    Publication date: June 22, 2023
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Patent number: 11672863
    Abstract: This invention describes compositions comprising at least 75 mg/mL of solubilized otherwise poorly soluble drug in an aqueous environment, wherein the composition further comprises a combination of 3 or more acids. Methods of providing analgesia, anti-pyretic effects or reducing pain in a subject presenting with a pain condition, and methods of reducing administration site irritation, inflammation or a combination thereof in a subject presenting with a pain condition, comprising the steps of administering such compositions and infusion pumps containing such compositions are also described.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: June 13, 2023
    Assignee: United Therapeutics Corporation
    Inventors: Michael Laird Hurrey, Drazen Ostovic, Peter Noymer
  • Patent number: 11602501
    Abstract: Lyophilized formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Grant
    Filed: October 4, 2021
    Date of Patent: March 14, 2023
    Assignee: Iterion Therapeutics, Inc.
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Patent number: 11571388
    Abstract: Lyophilized formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: February 7, 2023
    Assignee: Iterion Therapeutics, Inc.
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Publication number: 20220211649
    Abstract: The invention provides stable, aqueous capsaicin injectable formulations, a unit dose containing such injectable formulations, medical kits, and methods for using such injectable formulations and unit doses to treat patients suffering from pain, such as osteoarthritic knee pain. The stable, aqueous capsaicin injectable formulations may contain, for example, capsaicin, a solubilizing agent (e.g., a polyethylene glycol ester of a (C15-C25) hydroxyalkanoic acid), an antioxidant, and water.
    Type: Application
    Filed: March 22, 2022
    Publication date: July 7, 2022
    Inventors: Drazen Ostovic, Gary Fred Musso
  • Patent number: 11344516
    Abstract: The invention provides stable, aqueous capsaicin injectable formulations, a unit dose containing such injectable formulations, medical kits, and methods for using such injectable formulations and unit doses to treat patients suffering from pain, such as osteoarthritic knee pain. The stable, aqueous capsaicin injectable formulations may contain, for example, capsaicin, a solubilizing agent (e.g., a polyethylene glycol ester of a (C15-C25) hydroxyalkanoic acid), an antioxidant, and water.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: May 31, 2022
    Assignee: Centrexion Therapeutics Corporation
    Inventors: Drazen Ostovic, Gary Fred Musso
  • Publication number: 20220160635
    Abstract: Lyophilized formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Application
    Filed: November 24, 2020
    Publication date: May 26, 2022
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Publication number: 20220160637
    Abstract: Lyophilized formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Application
    Filed: October 4, 2021
    Publication date: May 26, 2022
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Publication number: 20220160636
    Abstract: Lyophilized formulations of tegavivint, methods of making such formulations, and methods of treatment of cancer by administering the formulations.
    Type: Application
    Filed: June 23, 2021
    Publication date: May 26, 2022
    Inventors: Gowri Sukumar, Drazen Ostovic
  • Publication number: 20220098173
    Abstract: The present invention relates to crystalline forms of (9E,10E)-2,7-bis((3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime, pharmaceutical compositions comprising the crystalline form, processes for preparing the crystalline form and methods of use therefore.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 31, 2022
    Inventors: Drazen Ostovic, Gowri Sukumar
  • Patent number: 11136307
    Abstract: The present invention relates to crystalline forms of (9E,10E)-2,7-bis((3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime, pharmaceutical compositions comprising the crystalline form, processes for preparing the crystalline form and methods of use therefore.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: October 5, 2021
    Assignee: ITERION THERAPEUTICS, INC.
    Inventors: Drazen Ostovic, Gowri Sukumar
  • Patent number: 11000490
    Abstract: The invention provides stable, aqueous capsaicin injectable formulations, a unit dose containing such injectable formulations, medical kits, and methods for using such injectable formulations and unit doses to treat patients suffering from pain, such as osteoarthritic knee pain. The stable, aqueous capsaicin injectable formulations may contain, for example, capsaicin, a solubilizing agent (e.g., a polyethylene glycol ester of a (C15-C25) hydroxyalkanoic acid), an antioxidant, and water.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: May 11, 2021
    Assignee: Centrexion Therapeutics Corporation
    Inventors: Drazen Ostovic, Gary Fred Musso
  • Publication number: 20210052522
    Abstract: The invention provides stable, aqueous capsaicin injectable formulations, a unit dose containing such injectable formulations, medical kits, and methods for using such injectable formulations and unit doses to treat patients suffering from pain, such as osteoarthritic knee pain. The stable, aqueous capsaicin injectable formulations may contain, for example, capsaicin, a solubilizing agent (e.g., a polyethylene glycol ester of a (C15-C25) hydroxyalkanoic acid), an antioxidant, and water.
    Type: Application
    Filed: September 11, 2020
    Publication date: February 25, 2021
    Inventors: Drazen Ostovic, Gary Fred Musso
  • Patent number: 10772853
    Abstract: The invention provides stable, aqueous capsaicin injectable formulations, a unit dose containing such injectable formulations, medical kits, and methods for using such injectable formulations and unit doses to treat patients suffering from pain, such as osteoarthritic knee pain. The stable, aqueous capsaicin injectable formulations may contain, for example, capsaicin, a solubilizing agent (e.g., a polyethylene glycol ester of a (C15-C25) hydroxyalkanoic acid), an antioxidant, and water.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: September 15, 2020
    Assignee: Centrexion Therapeutics Corporation
    Inventors: Drazen Ostovic, Gary Fred Musso