Abstract: The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing Parkinson's Disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention.

Abstract: A hyperspectral holographic polymer dispersed liquid crystal (HPDLC) medium comprising broadband reflective properties may comprise dopants that result in a hyperspectral HPDLC with fast transitional switching speeds. Dopants may include alliform carbon particles, carbon nanoparticles, piezoelectric nanoparticles, multiwalled carbon nanotubes, a high dielectric anisotropy compound, semiconductor nanoparticles, electrically conductive nanoparticles, metallic nanoparticles, or the like. A technique for fabrication of hyperspectral broadband HPDLC mediums may involve dynamic variation of the holography setup during HPDLC formation and spatial multiplexing that may enable broadening of the HPDLC medium's wavelength response. Fabrication may include concurrently running multiple exposures and exploiting superpositioning of the resultant gratings. The hyperspectral HPDLC may be capable of blocking and/or filtering wavelengths in the range of approximately 390 nm to approximately 12 ?m.

Abstract: The invention provides a peptide triazole conjugate and derivatives thereof, and methods of its use. The invention also provides an antibody to the peptide triazole conjugate. The invention further provides a method of identifying an HIV-1 entry inhibitor candidate.

Abstract: A single sensing probe comprising multiple, spatially separate, sensing sites is utilized to sense neural activity. The sensing probe includes multiple conductors each with multiple sensing sites in a fixed geometric arrangement. The sensing probe is configured to comprise multiple combined sensing sites in polytrode configuration. By appropriately combining the wire groupings at each combined sensing site, activity sensed from a single wire with multiple sensing sites, can be coupled with other wires to unmix signals from the spatially separate sites and leverage the power of combinatorics to maximize total recording bandwidth and single neuron/unit yield per wire and per probe.

Abstract: The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.

Abstract: Device and methods for use of these devices to manipulate substantially non-magnetic particles dispersed inside a magnetic fluid by employing a changeable pattern of local magnetic field maxima and minima are provided.

Abstract: The present invention is directed to methods of preparing nanoprobes, including multifunctional cellular endoscope-like devices, comprising nanotubes, nanorods, and/or nanowires.