Patents by Inventor Duan Jun Chen

Duan Jun Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fiber-optic assay apparatus based on phase-shift interferometry
    Patent number: 8305585
    Abstract: Apparatus and method for detecting the presence or amount or rate of binding of an analyte in a sample solution is disclosed. The apparatus includes an optical assembly having first and second reflecting surfaces separated by a distance “d” greater than 50 nm, where the first surface is formed by a layer of analyte-binding molecules, and a light source for directing a beam of light onto said first and second reflecting surface. A detector in the apparatus operates to detect a change in the thickness of the first reflecting layer resulting from binding of analyte to the analyte-binding molecules, when the assembly is placed in the solution of analyte, by detecting a shift in phase of light waves reflected from the first and second surfaces.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: November 6, 2012
    Assignee: Pall Corporation
    Inventors: Hong Tan, Yushan Tan, Duan Jun Chen, Krista Leah Witte
  • Fiber-Optic Assay Apparatus Based On Phase-Shift Interferometry
    Publication number: 20100238453
    Abstract: Apparatus and method for detecting the presence or amount or rate of binding of an analyte in a sample solution is disclosed. The apparatus includes an optical assembly having first and second reflecting surfaces separated by a distance “d” greater than 50 nm, where the first surface is formed by a layer of analyte-binding molecules, and a light source for directing a beam of light onto said first and second reflecting surface. A detector in the apparatus operates to detect a change in the thickness of the first reflecting layer resulting from binding of analyte to the analyte-binding molecules, when the assembly is placed in the solution of analyte, by detecting a shift in phase of light waves reflected from the first and second surfaces.
    Type: Application
    Filed: May 28, 2010
    Publication date: September 23, 2010
    Applicant: ForteBio, Inc.
    Inventors: Hong Tan, Duan Jun Chen, Yushan Tan, Krista Leah Witte
  • Fiber-optic assay apparatus based on phase-shift interferometry
    Patent number: 7728982
    Abstract: Apparatus and method for detecting the presence or amount or rate of binding of an analyte in a sample solution is disclosed. The apparatus includes an optical assembly having first and second reflecting surfaces separated by a distance “d” greater than 50 nm, where the first surface is formed by a layer of analyte-binding molecules, and a light source for directing a beam of light onto said first and second reflecting surface. A detector in the apparatus operates to detect a change in the thickness of the first reflecting layer resulting from binding of analyte to the analyte-binding molecules, when the assembly is placed in the solution of analyte, by detecting a shift in phase of light waves reflected from the first and second surfaces.
    Type: Grant
    Filed: April 8, 2008
    Date of Patent: June 1, 2010
    Assignee: ForteBio, Inc.
    Inventors: Hong Tan, Yushan Tan, Duan Jun Chen, Krista Leah Witte
  • Fiber-optic assay apparatus based on phase-shift interferometry
    Publication number: 20080186505
    Abstract: Apparatus and method for detecting the presence or amount or rate of binding of an analyte in a sample solution is disclosed. The apparatus includes an optical assembly having first and second reflecting surfaces separated by a distance “d” greater than 50 nm, where the first surface is formed by a layer of analyte-binding molecules, and a light source for directing a beam of light onto said first and second reflecting surface. A detector in the apparatus operates to detect a change in the thickness of the first reflecting layer resulting from binding of analyte to the analyte-binding molecules, when the assembly is placed in the solution of analyte, by detecting a shift in phase of light waves reflected from the first and second surfaces.
    Type: Application
    Filed: April 8, 2008
    Publication date: August 7, 2008
    Applicant: ForteBio, Inc.
    Inventors: Hong Tan, Duan Jun Chen, Yushan Tan, Krista Leah Witte
  • Fiber-optic assay apparatus based on phase-shift interferometry
    Patent number: 7394547
    Abstract: Apparatus and method for detecting the presence or amount or rate of binding of an analyte in a sample solution is disclosed. The apparatus includes an optical assembly having first and second reflecting surfaces separated by a distance “d” greater than 50 nm, where the first surface is formed by a layer of analyte-binding molecules, and a light source for directing a beam of light onto said first and second reflecting surface. A detector in the apparatus operates to detect a change in the thickness of the first reflecting layer resulting from binding of analyte to the analyte-binding molecules, when the assembly is placed in the solution of analyte, by detecting a shift in phase of light waves reflected from the first and second surfaces.
    Type: Grant
    Filed: November 4, 2004
    Date of Patent: July 1, 2008
    Assignee: ForteBio, Inc.
    Inventors: Hong Tan, Duan Jun Chen, Yushan Tan, Krista Leah Witte