Patents by Inventor Duan Li Ou

Duan Li Ou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210146015
    Abstract: A novel two-step process for batch coating surgical needles with cross-linked silicone coatings is disclosed. The surgical needles are cured using a two-step process. The coatings on the needles are partially cured in the first step and mechanically separated. The coatings on the needles are then fully cured in the second step.
    Type: Application
    Filed: November 24, 2020
    Publication date: May 20, 2021
    Applicant: Ethicon, Inc.
    Inventor: Duan Li Ou
  • Publication number: 20210130978
    Abstract: A low-hazardous electropolishing process has been developed to remove oxide layer(s) from the surface of nitinol needles. Low concentrations of citric acid and sulfamic acid are mixed with medium concentrations of sulfuric acid to use as an electrolyte solution. The process can be easily fitted into current suture needle manufacturing processes as well as into processes require electropolishing of nitinol-containing medical devices.
    Type: Application
    Filed: November 5, 2019
    Publication date: May 6, 2021
    Applicant: Ethicon LLC
    Inventor: Duan Li Ou
  • Patent number: 10934462
    Abstract: The invention describes compositions that include amine-containing silsesquioxane or an amine-containing alkyltrialkoxysilane and a thermoplastic elastomer as well as methods of preparation of the compositions that are useful as self-bonding adhesives for various substrates.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: March 2, 2021
    Assignee: Saint-Gobain Performance Plastics Corporatoin
    Inventor: Duan Li Ou
  • Patent number: 10874773
    Abstract: A novel two-step process for batch coating surgical needles with cross-linked silicone coatings is disclosed. The surgical needles are cured using a two-step process. The coatings on the needles are partially cured in the first step and mechanically separated. The coatings on the needles are then fully cured in the second step.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: December 29, 2020
    Assignee: Ethicon, Inc.
    Inventor: Duan Li Ou
  • Publication number: 20200391253
    Abstract: A non-hazardous cleaning solution/process has been developed to remove oxide residues from the surface of blackened needles. Low concentrations of citric acid solution are mixed with blackened needles and treated in an ultrasonic tank for short period of time (<5 minutes). The oxide residues are substantially removed. Quite surprisingly and unexpectedly, the penetration performance of the cleaned needles are greatly improved by up to 50% over other tested cleaning solutions.
    Type: Application
    Filed: June 12, 2019
    Publication date: December 17, 2020
    Applicant: Ethicon, Inc.
    Inventors: Duan Li Ou, Christophe Vailhe
  • Publication number: 20200268375
    Abstract: A needle and suture assembly includes a needle made of a superelastic alloy, such as Nitinol, including an elongated body having a proximal end and a distal end with a sharpened tip, a suture having a free end juxtaposed with the proximal end of the elongated body of the needle, and a connector disposed between the needle and the suture. The connector includes a first end attached to the proximal end of the elongated body of the needle and a second end attached to the free end of the suture. The connector is made of a material, such as stainless steel, having less elasticity and greater plasticity than the superelastic alloy of the needle.
    Type: Application
    Filed: February 22, 2019
    Publication date: August 27, 2020
    Inventors: Frank Richard Cichocki, JR., Christophe Vailhe, Thomas Nering, Alexander M. Cannara, Duan Li Ou
  • Publication number: 20200171528
    Abstract: The present disclosure provides a coating applicator operable to apply a coating of a therapeutic agent upon an object comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, an atomizer operable to atomize the therapeutic agent, and a source of vacuum in communication with the device compartment. The coating applicator may further comprise a drier, and the drier may comprise an arrangement to operate the source of vacuum for a time sufficient to promote drying of applied therapeutic agent. Deposition of the atomized therapeutic agent may be promoted by contacting the atomized therapeutic agent while the object is in a chilled condition and by contacting the object with atomized therapeutic agent while the atomized therapeutic agent is in a heated condition. Related methods are also disclosed.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 4, 2020
    Applicant: Ethicon, Inc.
    Inventors: Frank Richard Cichocki, Duan Li Ou
  • Publication number: 20200171532
    Abstract: Novel apparatus and methods for coating surgical needles in batch processes are disclosed.
    Type: Application
    Filed: February 4, 2020
    Publication date: June 4, 2020
    Inventors: Alexander M. Cannara, Frank Richard Cichocki, JR., Duan Li Ou
  • Publication number: 20200172740
    Abstract: Novel, lubricious antimicrobial coatings for medical devices are disclosed. The coatings provide improved lubricity and durability and are readily applied in coating processes at low temperatures that do not deform the device and preserves the antimicrobial effectiveness of the antimicrobial agent. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 4, 2020
    Applicant: Ethicon, Inc.
    Inventors: Duan Li Ou, Frank Richard Cichocki
  • Publication number: 20200171198
    Abstract: Novel, lubricious coatings for medical devices are disclosed. The coatings provide improved lubricity and durability and are readily applied in coating processes a low temperatures that do not deform the device. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 4, 2020
    Applicant: Ethicon, Inc.
    Inventors: Duan Li Ou, Christophe Vailhe, Frank Richard Cichocki
  • Publication number: 20200171209
    Abstract: The present disclosure provides a coating apparatus and method for applying a coating of a therapeutic agent, comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, a thermal source for vaporizing the therapeutic agent, and a vacuum source in fluid communication with the device compartment.
    Type: Application
    Filed: November 27, 2019
    Publication date: June 4, 2020
    Applicant: Ethicon, Inc.
    Inventors: Frank Richard Cichocki, Duan Li Ou
  • Publication number: 20200148832
    Abstract: Provided are rapidly cross-linkable silicone compositions, systems, kits, and methods for filling implanted medical devices in situ, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; and a silicone cross-linker, where the rapidly cross-linkable silicone composition has a viscosity of ?150 cPs for ?1 min. post-preparation and ?300 cPs?5 min. post-preparation, at ambient temperature.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: Duan Li OU, Leo B. KRIKSUNOV, Lamar KIRCHHEVEL, Clifford DWYER
  • Publication number: 20200146810
    Abstract: Provided are rapidly cross-linkable silicone foam compositions, kits, and methods for filling implanted medical devices in situ or in vivo, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; a silicone cross-linker; and a gas and/or gas-filled microcapsules, where the rapidly cross-linkable silicone foam composition has a viscosity of ?150 cPs for ?1 min. post-preparation and ?300 cPs?5 min. post-preparation, at ambient temperature.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: Duan Li OU, Leo B. KRIKSUNOV
  • Patent number: 10589313
    Abstract: Novel apparatus and methods for coating surgical needles in batch processes are disclosed. The apparatus and methods are particularly useful for applying uniform silicone lubricious coatings to surgical needles in bulk quantities using a novel separation and spray coating system and method.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: March 17, 2020
    Assignee: Ethicon, Inc.
    Inventors: Alexander M. Cannara, Frank Richard Cichocki, Jr., Duan Li Ou
  • Publication number: 20200046873
    Abstract: A method of reducing surgical site infection (SSI), using a coated medical device having a tissue penetrating surface and an abradable coating on the medical device comprising at least one antimicrobial agent in the coating.
    Type: Application
    Filed: August 13, 2018
    Publication date: February 13, 2020
    Inventors: Duan Li OU, Robert J. TANNHAUSER, Leo B. KRIKSUNOV
  • Patent number: 10533074
    Abstract: Provided are rapidly cross-linkable silicone compositions, systems, kits, and methods for filling implanted medical devices in situ, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; and a silicone cross-linker, where the rapidly cross-linkable silicone composition has a viscosity of ?150 cPs for ?1 min. post-preparation and ?300 cPs?5 min. post-preparation, at ambient temperature.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: January 14, 2020
    Assignee: ETHICON, INC.
    Inventors: Duan Li Ou, Leo B. Kriksunov, Lamar Kirchhevel, Clifford Dwyer
  • Patent number: 10531949
    Abstract: Provided are rapidly cross-linkable silicone foam compositions, kits, and methods for filling implanted medical devices in situ or in vivo, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; a silicone cross-linker; and a gas and/or gas-filled microcapsules, where the rapidly cross-linkable silicone foam composition has a viscosity of ?150 cPs for ?1 min. post-preparation and ?300 cPs?5 min. post-preparation, at ambient temperature.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: January 14, 2020
    Assignee: ETHICON, INC.
    Inventors: Duan Li Ou, Leo B. Kriksunov
  • Patent number: 10465094
    Abstract: A silicone coating process that improves the durability of silicone coatings on the surfaces of surgical needles and other medical devices. The silicone coated surgical needles or medical devices produced by this process have both superior lubricity and durability for ease of repeated and successive passes through tissue. The coating compositions used in the novel process contain an excess amount of polymethylhydrosiloxane cross-linker. After curing, the process utilizes gamma radiation to treat the lubricious coatings. The coatings have improved durability and performance. The penetration performance of needles coated by this novel method remains constant and flat over at least one hundred repeat passes through tissue or tissue simulation media. This provides a consistent or flat tactile response from the needles to the hand of the surgeon during a lengthy closure process, rather than an unpredictably increasing force profile.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: November 5, 2019
    Assignee: Ethicon, Inc.
    Inventor: Duan Li Ou
  • Patent number: 10441947
    Abstract: Novel, lubricious coatings for medical devices are disclosed. The coatings provide improved lubricity and durability, and are readily applied in coating processes. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: October 15, 2019
    Assignee: Ethicon, Inc.
    Inventor: Duan Li Ou
  • Publication number: 20190301024
    Abstract: A novel method of blackening surgical needles is disclosed. Surgical needles having outer surfaces are first placed into a first pretreatment bath having a novel composition. The needles are then placed into a second blackening bath having a novel composition for a sufficient period of time to effectively blacken the surfaces of the needles. The novel methods for blackening the surfaces of a stainless steel alloy surgical needle provide a chromium (VI)-free alternative to current needle manufacturing processes. Another unique feature of this novel method is its short processing time. The blackening processes of the present invention can be utilized for in-line treatment processes which can be easily incorporated into high speed needle manufacturing processes, such as strip mounted processes. In addition, the processes of the present invention are readily adaptable to batch processes. Also disclosed are novel systems for blackening surgical needles and novel blackening baths for surgical needles.
    Type: Application
    Filed: June 11, 2019
    Publication date: October 3, 2019
    Inventors: Duan Li Ou, Christophe Vailhe, Inas Alhamyery