Patents by Inventor Duanjie Hou

Duanjie Hou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic Heterocyclic Derivatives and Their Use as Inhibitors of Stearoyl-Coadesaturase (Scd)
    Publication number: 20070219211
    Abstract: Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise, for example, administering to a mammal in need thereof a compound of formula (I): where x, y, J, K, L, M, W, V, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
    Type: Application
    Filed: September 20, 2005
    Publication date: September 20, 2007
    Applicant: XENON PHARMACEUTICALS INC.
    Inventors: Rajender Kamboj, Jian-Min Fu, Vishnumurthy Kodumuru, Shifeng Liu, Kashinath Sadalapure, Nagasree Chakka, Duanjie Hou, Shaoyi Sun
  • Oxindole compounds and their uses as therapeutic agents
    Publication number: 20070105820
    Abstract: This invention is directed to oxindole compounds that are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also disclosed.
    Type: Application
    Filed: April 20, 2006
    Publication date: May 10, 2007
    Applicant: Xenon Pharmaceuticals Inc.
    Inventors: Mikhail Chafeev, Nagasree Chakka, Sultan Chowdhury, Robert Fraser, Jianmin Fu, Duanjie Hou, Tom Hsieh, Rajender Kamboj, Shifeng Liu, Vandna Raina, Mehran Seid Bagherzadeh, Jianyu Sun, Shaoyi Sun, Serguei Sviridov
  • Spiro-oxindole compounds and their uses as therapeutic agents
    Publication number: 20060252812
    Abstract: This invention is directed to spiro-oxindole compounds of formula (I): wherein k, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of preparing and using the compounds are also disclosed.
    Type: Application
    Filed: April 11, 2006
    Publication date: November 9, 2006
    Applicant: Xenon Pharmaceuticals Inc.
    Inventors: Mikhail Chafeev, Nagasree Chakka, Sultan Chowdhury, Robert Fraser, Jianmin Fu, Duanjie Hou, Tom Hsieh, Rajender Kamboj, Shifeng Liu, Vandna Raina, Mehran Bagherzadeh, Jianyu Sun, Shaoyi Sun, Serguei Sviridov
  • Pyridazine derivatives and their use as therapeutic agents
    Publication number: 20060009459
    Abstract: Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (Ia): where x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 and R9a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
    Type: Application
    Filed: February 9, 2005
    Publication date: January 12, 2006
    Inventors: Nagasree Chakka, Mikhail Chafeev, Sultan Chowdhury, Jian-Min Fu, Duanjie Hou, Rajender Kamboj, Vishnumurthy Kodumuru, Shifeng Liu, Vandna Raina, Shaoyi Sun, Serguei Sviridov, Michael Winther, Zaihui Zhang, Melwyn Abreo, Mark Holladay, Wenbao Li, Sengen Sun, Chi Tu, Heinz Gschwend
  • Pyridazine derivatives and their use as therapeutic agents
    Publication number: 20050065143
    Abstract: Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 and R9a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
    Type: Application
    Filed: July 29, 2004
    Publication date: March 24, 2005
    Applicant: Xenon Pharmaceuticals Inc.
    Inventors: Nagasree Chakka, Mikhail Chafeev, Sultan Chowdhury, Jian-Min Fu, Duanjie Hou, Rajender Kamboj, Vishnumurthy Kodumuru, Shifeng Liu, Vandna Raina, Shaoyi Sun, Serguei Sviridov, Michael Winther, Zaihui Zhang, Melwyn Abreo, Mark Holladay, Wenbao Li, Sengen Sun, Chi Tu, Heinz Gschwend
  • Novel derivatives of androstane and androstene with ascorbic acid and use thereof in treating or preventing various conditions, diseases, and disorders
    Publication number: 20030232797
    Abstract: The present invention provides novel derivatives comprising compounds in the androstane and androstene series, coupled with ascorbic acid, including salts thereof, and represented by one or more of the general formulae: 1
    Type: Application
    Filed: June 6, 2002
    Publication date: December 18, 2003
    Applicant: FORBES MEDI-TECH INC.
    Inventors: James P. Kutney, Hongming Chen, Duanjie Hou, Changqing Wang
  • Novel structures comprising phytosterol and/or phytostanol and ascorbic acid and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders
    Publication number: 20020156051
    Abstract: Novel phytosterol and/or phytostanol derivatives, including salts thereof, are represented by the general formulae: 1
    Type: Application
    Filed: July 25, 2001
    Publication date: October 24, 2002
    Applicant: FORBES MEDI-TECH INC.
    Inventors: James P. Kutney, Radka K. Milanova, Yangbing Ding, Hongming Chen, Duanjie Hou