Abstract: A method of assessing a bodily fluid sample on a test strip may involve applying a periodic signal with a first electrode located at a first location in a microfluidic channel of the test strip, monitoring the applied periodic signal with a second electrode located at a second location in the microfluidic channel, and using a third electrode located at a third location in the microfluidic channel as a reference electrode. The method may also include: collecting the bodily fluid sample in the microfluidic channel; continuing to apply the periodic signal, monitor the periodic signal and use the third electrode as a reference electrode while collecting the bodily fluid sample; and determining that the bodily fluid sample is sufficient for analyzing, based at least in part on the applied and monitored periodic signal.

Abstract: A method of assessing a bodily fluid sample on a test strip may involve applying a periodic signal with a first electrode located at a first location in a microfluidic channel of the test strip, monitoring the applied periodic signal with a second electrode located at a second location in the microfluidic channel, and using a third electrode located at a third location in the microfluidic channel as a reference electrode. The method may also include: collecting the bodily fluid sample in the microfluidic channel; continuing to apply the periodic signal, monitor the periodic signal and use the third electrode as a reference electrode while collecting the bodily fluid sample; and determining that the bodily fluid sample is sufficient for analyzing, based at least in part on the applied and monitored periodic signal.

Abstract: A system receives a circuit description and measures of intrinsic delay, intrinsic delay variation, transition time and transition time variation for each stage and determines stage delay variation of each stage. The system receives a circuit description and derate factors and determines an intrinsic delay standard deviation and a correlation coefficient. The system determines a stage delay variation of each stage based on the determined factors. The system receives parameters describing an asymmetric distribution of delay values and generates a normal distribution of delay values. The system receives measures of nominal transition time at an output and input of a wire, and transition time variation at the input of the wire and determines a transition time variation at the output of the wire. The system receives measures of an Elmore delay and a nominal delay of the wire and determines a delay variation at the output of the wire.

Abstract: A method of assessing a bodily fluid sample on a test strip may involve applying a periodic signal with a first electrode located at a first location in a microfluidic channel of the test strip, monitoring the applied periodic signal with a second electrode located at a second location in the microfluidic channel, and using a third electrode located at a third location in the microfluidic channel as a reference electrode. The method may also include: collecting the bodily fluid sample in the microfluidic channel; continuing to apply the periodic signal, monitor the periodic signal and use the third electrode as a reference electrode while collecting the bodily fluid sample; and determining that the bodily fluid sample is sufficient for analyzing, based at least in part on the applied and monitored periodic signal.

Abstract: The disclosure provides methods for detecting the concurrent presence of at least two targets within a biological sample. The method includes contacting said biological sample with a first binding agent, said first binding agent operably linked to a first sortase molecule, wherein said first binding agent specifically binds to a first target; contacting said biological simple with a second binding agent, said second binding agent operably linked to a first sortase recognition sequence peptide, wherein said second binding agent specifically binds to a second target; adding a sortase substrate under conditions where a first sortase-mediated ligation of the sortase substrate to the first sortase recognition sequence will produce a ligation product, and detecting the ligation product, wherein detection of said ligation product indicates the concurrent presence of the first target and the second target in the biological sample. Also disclosed are kits comprising reagents for performing the methods as claimed.

Abstract: A magnetometer for magnetic detection includes a magneto-optical defect center material having at least one magneto-optical defect center; a radio frequency (RF) exciter system including a radio frequency (RF) excitation source; an optical excitation system including an optical excitation source; an optical detector configured to receive an optical signal based on light emitted by the magneto-optical defect center material due RF excitation and optical excitation provided to the magneto-optical defect center material via the RF excitation source and the optical excitation source, respectively; a magnetic field generator configured to generate a magnetic field detected at the magneto-optical defect center material; and a system controller.

Abstract: A system receives a circuit description and measures of intrinsic delay, intrinsic delay variation, transition time and transition time variation for each stage and determines stage delay variation of each stage. The system receives a circuit description and derate factors and determines an intrinsic delay standard deviation and a correlation coefficient. The system determines a stage delay variation of each stage based on the determined factors. The system receives parameters describing an asymmetric distribution of delay values and generates a normal distribution of delay values. The system receives measures of nominal transition time at an output and input of a wire, and transition time variation at the input of the wire and determines a transition time variation at the output of the wire. The system receives measures of an Elmore delay and a nominal delay of the wire and determines a delay variation at the output of the wire.

Abstract: A system receives a circuit description and measures of intrinsic delay, intrinsic delay variation, transition time and transition time variation for each stage and determines stage delay variation of each stage. The system receives a circuit description and derate factors and determines an intrinsic delay standard deviation and a correlation coefficient. The system determines a stage delay variation of each stage based on the determined factors. The system receives parameters describing an asymmetric distribution of delay values and generates a normal distribution of delay values. The system receives measures of nominal transition time at an output and input of a wire, and transition time variation at the input of the wire and determines a transition time variation at the output of the wire. The system receives measures of an Elmore delay and a nominal delay of the wire and determines a delay variation at the output of the wire.

Abstract: A system for magnetic detection includes a magneto-optical defect center material including at least one magneto-optical defect center that emits an optical signal when excited by an excitation light; a radio frequency (RF) exciter system configured to provide RF excitation to the magneto-optical defect center material; an optical light source configured to direct the excitation light to the magneto-optical defect center material; and an optical detector configured to receive the optical signal emitted by the magneto-optical defect center material.

Abstract: The disclosure provides methods for detecting the concurrent presence of at least two targets within a biological sample. The method includes contacting said biological sample with a first binding agent, said first binding agent operably linked to a first sortase molecule, wherein said first binding agent specifically binds to a first target; contacting said biological sample with a second binding agent, said second binding agent operably linked to a first sortase recognition sequence peptide, wherein said second binding agent specifically binds to a second target; adding a sortase substrate under conditions where a first sortase-mediated ligation of the sortase substrate to the first sortase recognition sequence will produce a ligation product, and detecting the ligation product wherein detection of said ligation product indicates the concurrent presence of the first target and the second target in the biological sample. Also disclosed are kits comprising reagents for performing the methods as claimed.

Abstract: A magnetic separation device for immunoassay using a two-sided plate for multi-well microplate separation via a flat side containing a magnetic block and a back side of magnetic microplate structure containing a matrix of permanent magnets. The present invention relates to a multi-purpose magnetic separation device that has two sides of magnetic separation function. The flat side of magnetic separation device includes magnetic block, metal or plastic sheet surface top and a pin to secure the assay plate. The back side of magnetic separation device is a multi-well structure that includes a plurality of permanent magnets placed in the spaces between the adjacent wells. There are different magnetic configurations for the multi-well structure, which ensures that each well is pulled by at least one strong permanent magnet.

Abstract: A magnetic field sensor assembly includes a first radio frequency (RF) element; a second RF element; an RF feed cable operably connected to the first RF element and the second RF element that provides an RF signal to the first RF element and the second RF element; and a magneto-optical defect center material located between the first RF element and the second RF element. The first RF element and the second RF element generate a microwave signal that is uniform over the magneto-optical defect center material. The magneto-optical defect center material may be a nitrogen-vacancy center diamond.

Abstract: The subject of the present invention is an electronic control panel (1) for a motor vehicle, characterized in that it comprises a touch-sensitive screen (3), a touch-sensitive control surface (5) contiguous with said touch-sensitive screen, and a common support (33) for the touch-sensitive screen (3) and for the touch-sensitive control surface (5), the touch-sensitive screen (3) and the touch-sensitive control surface (5) being arranged on the common support (33) at the same level where they meet so as to define a near-continuous control area.

Abstract: A system for magnetic detection includes a housing including a top plate, bottom plate, side plate, and main plate provided between the side plate and the bottom plate; a magneto-optical defect center material including at least one magneto-optical defect center that emits an optical signal when excited by an excitation light; a radio frequency (RF) exciter system configured to provide RF excitation to the magneto-optical defect center material; an optical light source configured to direct the excitation light to the magneto-optical defect center material; and an optical detector configured to receive the optical signal emitted by the magneto-optical defect center material. The elements of the system are mounted to the main plate and capable of being unattached and remounted to the main plate to change at least one of a location or an angle of incidence of the excitation light on the magneto-optical defect center material.

Abstract: A magnetic separation device for immunoassay using a two-sided plate for multi-well microplate separation via a flat side containing a magnetic block and a back side of magnetic microplate structure containing a matrix of permanent magnets. The present invention relates to a multi-purpose magnetic separation device that has two sides of magnetic separation function. The flat side of magnetic separation device includes magnet block, metal or plastic sheet on top surface and a pin to secure the assay plate. The back side of magnetic separation device is a multi-well structure that includes a plurality of permanent magnets placed in the spaces between the adjacent wells. There are different magnetic configurations for the multi-well structure, which ensures that each well is pulled by at least one strong permanent magnet. These strong permanent magnets are polarized laterally, i.e., its magnetic flux line points toward the side of the well.

Abstract: A system receives a circuit description and measures of intrinsic delay, intrinsic delay variation, transition time and transition time variation for each stage and determines stage delay variation of each stage. The system receives a circuit description and derate factors and determines an intrinsic delay standard deviation and a correlation coefficient. The system determines a stage delay variation of each stage based on the determined factors. The system receives parameters describing an asymmetric distribution of delay values and generates a normal distribution of delay values. The system receives measures of nominal transition time at an output and input of a wire, and transition time variation at the input of the wire and determines a transition time variation at the output of the wire. The system receives measures of an Elmore delay and a nominal delay of the wire and determines a delay variation at the output of the wire.

Abstract: A system receives a circuit description and measures of intrinsic delay, intrinsic delay variation, transition time and transition time variation for each stage and determines stage delay variation of each stage. The system receives a circuit description and derate factors and determines an intrinsic delay standard deviation and a correlation coefficient. The system determines a stage delay variation of each stage based on the determined factors. The system receives parameters describing an asymmetric distribution of delay values and generates a normal distribution of delay values. The system receives measures of nominal transition time at an output and input of a wire, and transition time variation at the input of the wire and determines a transition time variation at the output of the wire. The system receives measures of an Elmore delay and a nominal delay of the wire and determines a delay variation at the output of the wire.

Abstract: A magnetometer for magnetic detection includes a magneto-optical defect center material having at least one magneto-optical defect center; a radio frequency (RF) exciter system including a radio frequency (RF) excitation source; an optical excitation system including an optical excitation source; an optical detector configured to receive an optical signal based on light emitted by the magneto-optical defect center material due RF excitation and optical excitation provided to the magneto-optical defect center material via the RF excitation source and the optical excitation source, respectively; a magnetic field generator configured to generate a magnetic field detected at the magneto-optical defect center material; and a system controller.

Abstract: A magneto-optical defect center magnetometer, such as a diamond nitrogen vacancy (DNV) magnetometer, can include an excitation source, a magneto-optical defect center element, a collection device, a top plate, a bottom plate, and a printed circuit board. The excitation source, the magneto-optical defect center element, and the collection device are each mounted to the printed circuit board.

Abstract: A command device (6) for at least one function of a motor vehicle, the device comprising: —a touchpad (1) configured to receive a command of said at least one function, —at least one antenna (3,4) arranged around the touchpad (1) in such a way as to frame said touchpad (1), the antenna (3,4) being capable of forming a capacitor with at least one exterior element (2,5) in contact with the touchpad (1), —means for measuring (8) the capacitance of the capacitor formed by the antenna (3,4) and said at least one exterior element (2,5), and —a means of control of the command (9) configured so as to take account of the command received by the touchpad (1) when the capacitance measured by the measurement means (8) lies in a predetermined interval.