Patents by Inventor Dufei Fang

Dufei Fang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8222166
    Abstract: Membranes suitable for microfiltration, ultrafiltration (UF) and nanofiltration (NF) filters are provided. Such membranes may include a nanofibrous scaffold, optionally in combination with a non-woven substrate and/or a coating of a polymer and a functionalized nanofiller. Suitable membranes may also include a coating of a polymer and a functionalized nanofiller on a substrate, which can include a non-woven membrane, a nanofibrous scaffold, or both.
    Type: Grant
    Filed: October 5, 2005
    Date of Patent: July 17, 2012
    Assignee: The Research Foundation of State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Dufei Fang, Kwang-Sok Kim
  • Patent number: 8021869
    Abstract: Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and release the cells at a controlled rate. The biodegradable and/or bioabsorbable matrix can be formed by electrospinning fibers of biodegradable and/or bioabsorbable fiberizable material. The methods include methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system.
    Type: Grant
    Filed: November 20, 2007
    Date of Patent: September 20, 2011
    Assignee: The Research Foundation of State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Michael Hadjiargyrou, Dufei Fang, Xinhua Zong, Kwangsok Kim
  • Patent number: 7934917
    Abstract: A spinneret format, an electric-field reversal format and a process for post-treatment of membranes formed from electro-spinning or electro-blowing are provided, including a cleaning method and apparatus for electro-blowing or blowing-assisted electro-spinning technology.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: May 3, 2011
    Assignee: The Research Foundation of State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Dufei Fang
  • Patent number: 7887311
    Abstract: A spinneret format, an electric-field reversal format and a process for post-treatment of membranes formed from electro-spinning or electro-blowing are provided, including a cleaning method and apparatus for electro-blowing or blowing-assisted electro-spinning technology.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: February 15, 2011
    Assignee: The Research Foundation of State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsaio, Dufei Fang
  • Publication number: 20100323573
    Abstract: Membranes suitable for microfiltration, ultrafiltration (UF) and nanofiltration (NF) filters are provided. Such membranes may include a nanofibrous scaffold, optionally in combination with a non-woven substrate and/or a coating of a polymer and a functionalized nanofiller. Suitable membranes may also include a coating of a polymer and a functionalized nanofiller on a substrate, which can include a non-woven membrane, a nanofibrous scaffold, or both.
    Type: Application
    Filed: October 5, 2005
    Publication date: December 23, 2010
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Dufei Fang, Kwang-sok Kim
  • Patent number: 7662332
    Abstract: A method for electroblowing fibers is provided which involves the steps of: forcing a polymer fluid through a spinneret in a first direction towards a collector located a first distance from the spinneret, while simultaneously blowing a gas through an orifice that is substantially concentrically arranged around the spinneret, wherein the gas is blown substantially in the first direction; wherein an electrostatic differential is generated between the spinneret and the collector; and collecting the fibers, and its use in preparing submicron scale fibers of various types, particularly hyaluronan fibers, and the hyaluronan nanofibers thus formed.
    Type: Grant
    Filed: October 1, 2003
    Date of Patent: February 16, 2010
    Assignee: The Research Foundation of State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Dufei Fang, Akio Okamoto
  • Publication number: 20090155340
    Abstract: Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and release the cells at a controlled rate. The biodegradable and/or bioabsorbable matrix can be formed by electrospinning fibers of biodegradable and/or bioabsorbable fiberizable material. The methods include methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system.
    Type: Application
    Filed: November 20, 2007
    Publication date: June 18, 2009
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Michael Hadjiargyrou, Dufei Fang, Xinhua Zong, Kwangsok Kim
  • Publication number: 20090121379
    Abstract: A spinneret format, an electric-field reversal format and a process for post-treatment of membranes formed from electro-spinning or electro-blowing are provided, including a cleaning method and apparatus for electro-blowing or blowing-assisted electro-spinning technology.
    Type: Application
    Filed: September 23, 2008
    Publication date: May 14, 2009
    Applicant: The Research Foundation of SUNY
    Inventors: Benjamin Chu, Benjamin S. Hsaio, Dufei Fang
  • Publication number: 20090123591
    Abstract: A spinneret format, an electric-field reversal format and a process for post-treatment of membranes formed from electro-spinning or electro-blowing are provided, including a cleaning method and apparatus for electro-blowing or blowing-assisted electro-spinning technology.
    Type: Application
    Filed: September 23, 2008
    Publication date: May 14, 2009
    Applicant: The Research Foundation of SUNY
    Inventors: Benjamin Chu, Benjamin S. Hsaio, Dufei Fang
  • Patent number: 7323425
    Abstract: A method for producing a non-chemically crosslinked hyaluronan is provided which involves contacting a sample of hyaluronan with an acidic solvent/water mixture for a period of time and at a temperature sufficient to effect crosslinking, wherein the acidic solvent/water mixture has a content of a solvent sufficient to prevent dissolution of said hyaluronan and wherein the solvent is miscible with water, and an amount of an acid sufficient to effect crosslinking of the hyaluronan, and the crosslinked, water resistant non-woven hyaluronan resulting therefrom.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: January 29, 2008
    Assignee: Stony Brook Technology and Applied Research
    Inventors: Benjamin Chu, Benjamin S. Hsaio, Dufei Fang, Akio Okamoto
  • Patent number: 7323190
    Abstract: Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and release the cells at a controlled rate. The biodegradable and/or bioabsorable matrix can be formed by electrospinning fibers of biodegradable and/or bioabsorbable fiberizable material. The methods include methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system.
    Type: Grant
    Filed: August 17, 2004
    Date of Patent: January 29, 2008
    Assignee: The Research Foundation at State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Michael Hadjiargyrou, Dufei Fang, Xinhua Zong, Kwangsok Kim
  • Patent number: 7172765
    Abstract: Biodegradable and/or bioabsorable fibrous articles and methods for using the articles in medical applications are disclosed. The biodegradable and/or bioabsorable fibrous articles, which are formed by elctrospinning fibers of biodegradable and/or bioabsorbable fiberizable material, comprise a composite (or asymmetric composite) of different biodegradable and/or bioabsorbable fibers. Articles having specific medical uses include an adhesion-reducing barrier and a controlled delivery system. The methods include methods for reducing surgical adhesions, controlled delivery of a medicinal agent and providing controlled tissue healing.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: February 6, 2007
    Assignee: The Research Foundation of State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Dufei Fang, Collin Brathwaite
  • Patent number: 7037978
    Abstract: The invention relates to a quasi-interpenetrating network of polymer chains, the chains comprising linear polyacrylamide (LPA) chains in the form of a main frame having a weight average molecular weight of approximately 0.05 million to approximately 25 million g/mole, and a radius of gyration of approximately 10 nm to 350 nm; and polydimethylacrylamide (PDMA) chains prepared by polymerizing PDMA in the presence of the LPA main frame, wherein the LPA and PDMA chains are entangled within one another and interpenetrate one another, and wherein the quasi-interpenetrating network has substantially no chemical cross-linking.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: May 2, 2006
    Assignee: The Research Foundation of SUNY at Stony Brook
    Inventors: Benjamin Chu, Liguo Song, Dufei Fang, Dehai Liang, Tianbo Liu, Yanmei Wang, Qicong Ying
  • Publication number: 20060049542
    Abstract: A spinneret format, an electric-field reversal format and a process for post-treatment of membranes formed from electro-spinning or electro-blowing are provided, including a cleaning method and apparatus for electro-blowing or blowing-assisted electro-spinning technology.
    Type: Application
    Filed: September 9, 2004
    Publication date: March 9, 2006
    Inventors: Benjamin Chu, Benjamin Hsaio, Dufei Fang
  • Publication number: 20060046590
    Abstract: A method for producing a non-chemically crosslinked hyaluronan is provided which involves contacting a sample of hyaluronan with an acidic solvent/water mixture for a period of time and at a temperature sufficient to effect crosslinking, wherein the acidic solvent/water mixture has a content of a solvent sufficient to prevent dissolution of said hyaluronan and wherein the solvent is miscible with water, and an amount of an acid sufficient to effect crosslinking of the hyaluronan, and the crosslinked, water resistant non-woven hyaluronan resulting therefrom.
    Type: Application
    Filed: August 27, 2004
    Publication date: March 2, 2006
    Applicant: STONY BROOK TECHNOLOGY AND APPLIED RESEARCH
    Inventors: Benjamin Chu, Benjamin Hsaio, Dufei Fang, Akio Okamoto
  • Publication number: 20050073075
    Abstract: A method for electroblowing fibers is provided which involves the steps of: forcing a polymer fluid through a spinneret in a first direction towards a collector located a first distance from the spinneret, while simultaneously blowing a gas through an orifice that is substantially concentrically arranged around the spinneret, wherein the gas is blown substantially in the first direction; wherein an electrostatic differential is generated between the spinneret and the collector; and collecting the fibers, and its use in preparing submicron scale fibers of various types, particularly hyaluronan fibers, and the hyaluronan nanofibers thus formed.
    Type: Application
    Filed: October 1, 2003
    Publication date: April 7, 2005
    Applicant: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Benjamin Chu, Benjamin Hsiao, Dufei Fang, Akio Okamoto
  • Publication number: 20050070668
    Abstract: The invention relates to a quasi-interpenetrating network of polymer chains, the chains comprising linear polyacrylamide (LPA) chains in the form of a main frame having a weight average molecular weight of approximately 0.05 million to approximately 25 million g/mole, and a radius of gyration of approximately 10 nm to 350 nm; and polydimethylacrylamide (PDMA) chains prepared by polymerizing PDMA in the presence of the LPA main frame, wherein the LPA and PDMA chains are entangled within one another and interpenetrate one another, and wherein the quasi-interpenetrating network has substantially no chemical cross-linking.
    Type: Application
    Filed: September 25, 2003
    Publication date: March 31, 2005
    Inventors: Benjamin Chu, Liguo Song, Dufei Fang, Dehai Liang, Tianbo Liu, Yanmei Wang, Qicong Ying
  • Publication number: 20050014252
    Abstract: Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and release the cells at a controlled rate. The biodegradable and/or bioabsorable matrix can be formed by electrospinning fibers of biodegradable and/or bioabsorbable fiberizable material. The methods include methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system.
    Type: Application
    Filed: August 17, 2004
    Publication date: January 20, 2005
    Inventors: Benjamin Chu, Benjamin Hsiao, Michael Hadjiargyrou, Dufei Fang, Xinhua Zong, Kwangsok Kim
  • Patent number: 6790455
    Abstract: Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and release the cells at a controlled rate. The biodegradable and/or bioabsorbable matrix can be formed by electrospinning fibers of biodegradable and/or bioabsorbable fiberizable material. The methods include methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: September 14, 2004
    Assignee: The Research Foundation at State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Michael Hadjiargyrou, Dufei Fang, Xinhua Zong, Kwangsok Kim
  • Patent number: 6770698
    Abstract: The present invention is a polymer solution for the efficient separation of charged macromolecules by electrophoresis that includes a plurality of polymers. These polymers are entangled to form an interpenetrating network with greater entanglement times than corresponding homopolymers of the same length. These polymers are different and do not phase separate when dissolved in solution. Preferred polymers are PAM and PVP or PDAM and PVP. The polymer solutions of the present invention provide at least a 500-base read length in one run for a single-stranded DNA separation.
    Type: Grant
    Filed: June 5, 2000
    Date of Patent: August 3, 2004
    Assignee: The Research Foundation at State University of New York
    Inventors: Benjamin Chu, Liguo Song, Dufei Fang, Dehai Liang, Tianbo Liu