Patents by Inventor Dulce C. Veloso

Dulce C. Veloso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies to human plasma prekallikrein
    Patent number: 5444156
    Abstract: Four novel cell lines, ATCC #HB-8862 through ATCC #HB-8865 produce monoclonal antibody to human plasma prekallikrein. At least three of the antibodies also recognize plasma kallikrein, specifically the heavy chain thereof, and kallikrein-Cl-inhibitor complex; at least one of these three antibodies recognizes kallikrein-alpha.sub.2 -macroglobulin complex and kallikrein-antithrombin III complex. The antibodies do not cross-react with tissue kallikrein. The hybridomas are formed by fusing spleen cells from immunized BALB/c AnSkh mice with SP2/O-Agl4 myeloma cells. Diagnostic and biochemical uses of the monoclonal antibodies are provided.
    Type: Grant
    Filed: February 19, 1993
    Date of Patent: August 22, 1995
    Assignee: Temple University-of The Commonwealth System of Higher Education
    Inventors: Dulce C. Veloso, Robert W. Colman