Patents by Inventor Dumitru Arian

Dumitru Arian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromogenic And Fluorogenic Peptide Substrates For The Detection Of Serine Protease Activity
    Publication number: 20180215787
    Abstract: The present invention relates to chromogenic and fluorogenic substrates that can be used for the highly sensitive and selective detection of the activity of serine proteases. The present invention further relates to methods for the detection of the activity of serine proteases, said methods using the substrates of the present invention. Furthermore, the present invention relates to diagnostic kits and test strips using the above substrates, as well as uses of said substrates.
    Type: Application
    Filed: August 3, 2016
    Publication date: August 2, 2018
    Inventors: Roland Krämer, Dumitru Arian, Job Harenberg
  • Irreversible inhibitors of DNA polymerase beta
    Patent number: 9029346
    Abstract: Methods and compounds are disclosed for irreversibly inhibiting a DNA repair enzyme that possesses lyase activity.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: May 12, 2015
    Assignee: The Johns Hopkins University
    Inventors: Marc M. Greenberg, Dumitru Arian, Theodore L. Deweese, Mohammad Hedayati