Patents by Inventor Dumitru Mazilu

Dumitru Mazilu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230356001
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including Mill. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Application
    Filed: July 18, 2023
    Publication date: November 9, 2023
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Patent number: 11745027
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: September 5, 2023
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Patent number: 10646295
    Abstract: Featured is a medical instrument driver, a robotic apparatus embodying such a medical instrument driver and methods related thereto for inserting a medical instrument into tissue of a mammal (e.g., human). Such medical instruments include medical needles, biopsy needles, trocars, cutters and introducers. Such a medical instrument driver according to the present invention is configured and arranged so that medical instrument is rotated as it is being moved longitudinally for insertion into the tissue such that the medical instrument is spiraling as it pierces and traverses the tissue to the target area.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: May 12, 2020
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor, Dumitru Mazilu, Alexandru Patriciu, Lucian Gruionu
  • Publication number: 20200086140
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Application
    Filed: May 2, 2019
    Publication date: March 19, 2020
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Patent number: 10315046
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: June 11, 2019
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Patent number: 10024160
    Abstract: A stepper motor suitable for use in a medical imaging environment has (a) a cylindrical central gear having an external surface with circumferentially distributed and radially directed teeth, (b) a shaft for mounting the central gear such that it is constrained to move in rotational motion about its centerline, (c) a cylindrical hoop gear having a bore with an internal surface having circumferentially distributed and radially directed teeth, (d) level arm crank mechanisms for mounting the hoop gear such that it is constrained to move in translational-circular motion about the central gear's centerline, wherein this central gear is further configured to fit within the hoop gear's bore in such a manner that a plurality of the central gear and hoop gear teeth intermesh and cooperate so that the planetary movement of the hoop gear causes the central gear to rotate, and (e) piston mechanisms for applying a fluid pressure driven force to specified points on the hoop gear so as to cause its movement.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: July 17, 2018
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Publication number: 20170252115
    Abstract: Featured is a medical instrument driver, a robotic apparatus embodying such a medical instrument driver and methods related thereto for inserting a medical instrument into tissue of a mammal (e.g., human). Such medical instruments include medical needles, biopsy needles, trocars, cutters and introducers. Such a medical instrument driver according to the present invention is configured and arranged so that medical instrument is rotated as it is being moved longitudinally for insertion into the tissue such that the medical instrument is spiraling as it pierces and traverses the tissue to the target area.
    Type: Application
    Filed: February 17, 2017
    Publication date: September 7, 2017
    Inventors: Dan Stoianovici, Doru Petrisor, Dumitru Mazilu, Alexandru Patriciu, Lucian Gruionu
  • Patent number: 9610131
    Abstract: Featured is a medical instrument driver, a robotic apparatus embodying such a medical instrument driver and methods related thereto for inserting a medical instrument into tissue of a mammal (e.g., human). Such medical instruments include medical needles, biopsy needles, trocars, cutters and introducers. Such a medical instrument driver according to the present invention is configured and arranged so that medical instrument is rotated as it is being moved longitudinally for insertion into the tissue such that the medical instrument is spiraling as it pierces and traverses the tissue to the target area.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: April 4, 2017
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor, Dumitru Mazilu, Alexandru Patriciu, Lucian Gheorghe Gruionu
  • Patent number: 8403675
    Abstract: A training and/or evaluating device is provided particularly useful in performing laparoscopic procedures, radiological procedures, and precise surgeries that simulates the structure and dynamic motion of the corresponding anatomical structure on which the procedure takes place. The device includes an outer housing, which may be designed to mimic the body wall, in which one or more organs are located. Motion of the organ(s), as a result of respiration, pulmonary action, circulation, digestion and other factors present in a live body, is simulated in the device so as to provide accurate dynamic motion of the organs during a procedure.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: March 26, 2013
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Dumitru Mazilu, Alexandru Patriciu, Louis R. Kavoussi
  • Publication number: 20120076681
    Abstract: A stepper motor suitable for use in a medical imaging environment has (a) a cylindrical central gear having an external surface with circumferentially distributed and radially directed teeth, (b) a shaft for mounting the central gear such that it is constrained to move in rotational motion about its centerline, (c) a cylindrical hoop gear having a bore with an internal surface having circumferentially distributed and radially directed teeth, (d) level arm crank mechanisms for mounting the hoop gear such that it is constrained to move in translational-circular motion about the central gear's centerline, wherein this central gear is further configured to fit within the hoop gear's bore in such a manner that a plurality of the central gear and hoop gear teeth intermesh and cooperate so that the planetary movement of the hoop gear causes the central gear to rotate, and (e) piston mechanisms for applying a fluid pressure driven force to specified points on the hoop gear so as to cause its movement.
    Type: Application
    Filed: October 11, 2011
    Publication date: March 29, 2012
    Applicant: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Publication number: 20120035702
    Abstract: An expandable stent (12) for use in the implantation of a valve prosthesis (11) using a delivery system (10) is disclosed. The self-expandable stent (12) includes a tubular lattice structure (13) defined by longitudinally aligned rods (16) connected to V- shaped struts (17) for forming a plurality of interconnected chevron-shaped six-sided polygons (24) that define a distal end zone (21) and a middle zone (20) of the tubular lattice structure (13). A flare (27) or bend may be defined along opposite ends of each rod (16) to properly seat and prevent undue torsion of the stent (12) and valve prosthesis (11) during deployment and placement of the stent (12) within the lumen.
    Type: Application
    Filed: April 23, 2010
    Publication date: February 9, 2012
    Inventors: Keith Horvath, Dumitru Mazilu, Ming Li
  • Patent number: 8061262
    Abstract: A stepper motor suitable for use in a medical imaging environment has (a) a cylindrical central gear having an external surface with circumferentially distributed and radially directed teeth, (b) a shaft for mounting the central gear such that it is constrained to move in rotational motion about its centerline, (c) a cylindrical hoop gear having a bore with an internal surface having circumferentially distributed and radially directed teeth, (d) level arm crank mechanisms for mounting the hoop gear such that it is constrained to move in translational-circular motion about the central gear's centerline, wherein this central gear is further configured to fit within the hoop gear's bore in such a manner that a plurality of the central gear and hoop gear teeth intermesh and cooperate so that the planetary movement of the hoop gear causes the central gear to rotate, and (e) piston mechanisms for applying a fluid pressure driven force to specified points on the hoop gear so as to cause its movement.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: November 22, 2011
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Patent number: 7822466
    Abstract: A system and method for CT guided instrument targeting including a radiolucent instrument driver; a robot and a control box. The robot includes a robotic module that positions the radiolucent driver about two directions coincident a predetermined point. The control device is connected to the robot and the radiolucent instrument driver. The control driver sends a robot control signal to the robot that causes the robotic module to place the radiolucent instrument driver in a desired orientation with respect to the predetermined point. After the radiolucent instrument driver is in the desired orientation, the control device sends a driver control signal to the radiolucent instrument driver that causes the radiolucent driver to insert a medical instrument or device through the predetermined point to a location proximate a target point in a patient.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: October 26, 2010
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Dumitru Mazilu, Louis R. Kavoussi
  • Publication number: 20100240989
    Abstract: A system and method for CT guided instrument targeting including a radiolucent instrument driver; a robot and a control box. The robot includes a robotic module that positions the radiolucent driver about two directions coincident a predetermined point. The control device is connected to the robot and the radiolucent instrument driver. The control driver sends a robot control signal to the robot that causes the robotic module to place the radiolucent instrument driver in a desired orientation with respect to the predetermined point. After the radiolucent instrument driver is in the desired orientation, the control device sends a driver control signal to the radiolucent instrument driver that causes the radiolucent driver to insert a medical instrument or device through the predetermined point to a location proximate a target point in a patient.
    Type: Application
    Filed: April 25, 2003
    Publication date: September 23, 2010
    Inventors: Dan Stoianovici, Dumitru Mazilu, Louis R. Kavoussi
  • Publication number: 20100234856
    Abstract: Featured is a medical instrument driver, a robotic apparatus embodying such a medical instrument driver and methods related thereto for inserting a medical instrument into tissue of a mammal (e.g., human). Such medical instruments include medical needles, biopsy needles, trocars, cutters and introducers. Such a medical instrument driver according to the present invention is configured and arranged so that medical instrument is rotated as it is being moved longitudinally for insertion into the tissue such that the medical instrument is spiraling as it pierces and traverses the tissue to the target area.
    Type: Application
    Filed: November 5, 2009
    Publication date: September 16, 2010
    Applicant: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor, Dumitru Mazilu, Alexandru Patriciu, Lucian Gheorghe Gruionu
  • Publication number: 20100041938
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Application
    Filed: December 4, 2006
    Publication date: February 18, 2010
    Applicant: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Publication number: 20070034046
    Abstract: A stepper motor suitable for use in a medical imaging environment has (a) a cylindrical central gear having two ends with a center line extending between these ends, and an external surface with circumferentially distributed and radially directed teeth, (b) a means for mounting the central gear such that it is constrained to move in rotational motion about its centerline, (c) a cylindrical hoop gear having a bore with an internal surface having circumferentially distributed and radially directed teeth, (d) a means for mounting the hoop gear such that it is constrained to move in translational-circular motion about the central gear's centerline, wherein this central gear is further configured to fit within the hoop gear's bore in such a manner that a plurality of the central gear and hoop gear teeth intermesh, and wherein these hoop gear teeth are further configured so as to cooperate with the central gear teeth so that the planetary movement of the hoop gear teeth causes the central gear to rotate, and (e) a
    Type: Application
    Filed: February 22, 2006
    Publication date: February 15, 2007
    Applicant: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis Kavoussi
  • Patent number: 7021173
    Abstract: A remote center of motion robotic system including a base unit and a plurality of linking units. The base unit is rotatable about a first axis. The plurality of linking units are coupled with one another. At least two of the linking units are kept parallel to each another during motion. The plurality of linking units are coupled with that base unit at a first end. The plurality of linking units are rotatable about a second axis by changing an angle between each of the plurality of links.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: April 4, 2006
    Assignee: The John Hopkins University
    Inventors: Dan Stoianovici, Louis L. Whitcomb, Dumitru Mazilu, Russell H. Taylor, Louis R. Kavoussi
  • Publication number: 20050214727
    Abstract: A training and/or evaluating device is provided particularly useful in performing laparoscopic procedures, radiological procedures, and precise surgeries that simulates the structure and dynamic motion of the corresponding anatomical structure on which the procedure takes place. The device includes an outer housing, which may be designed to mimic the body wall, in which one or more organs are located. Motion of the organ(s), as a result of respiration, pulmonary action, circulation, digestion and other factors present in a live body, is simulated in the device so as to provide accurate dynamic motion of the organs during a procedure.
    Type: Application
    Filed: March 8, 2005
    Publication date: September 29, 2005
    Applicant: The Johns Hopkins University
    Inventors: Dan Stoianovici, Dumitru Mazilu, Alexandru Patriciu, Louis Kavoussi
  • Patent number: 6857609
    Abstract: A positioning arm for positioning and holding a device within a medical imaging environment workspace has: (a) a free-end link in the form of a circular cylinder having a distal end face and an adjoining end face, with the adjoining end face forming a specified angle with the cylinder's centerline and the distal end face adapted to allow for the connection of the device to the free-end link, (b) a plurality of intermediate links, each in the form of a circular cylinder having end faces that form a specified angle with the links' centerline, and each of these intermediate links having a channel connecting their end faces, (c) a base link in the form of a circular cylinder having a base end face and an adjoining end face, with the adjoining end face forming a specified angle with the link's centerline and the base end face adapted to allow for the connection of the arm to a supporting surface, (d) a cable that passes through the link channels so that one cable end attaches to the free-end link and the other end
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: February 22, 2005
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Keenan A. Wyrobek, Dumitru Mazilu, Louis L. Whitcomb