Abstract: A method of synthesising a compound of formula (I): (I) from a compound of formula (II): (II) where R8 is either: (i) ProtO3; or (ii) a group of formula (A1) in formula (I) and (A2) in formula (II): (A1), (A2).

Abstract: A method of synthesising a compound of formula (I): (I) from a compound of formula (II): (II) where R8 is either: (i) ProtO3; or (ii) a group of formula (A1) in formula (I) and (A2) in formula (II): (A1), (A2).

Abstract: An autonomous assembly that includes a gantry subassembly, a carrier subassembly movably mounted on the gantry subassembly, a tool actuation subassembly mounted on the carrier subassembly, and an autonomous control system including a perception subsystem, a motion planning subsystem, and a motion control subsystem. The gantry subassembly includes a bridge member for laterally spanning a selected section of a work site and a gantry drive system for effecting travel of the gantry subassembly along a first path, generally in a longitudinally along the length of the selected portion of a work site. The carrier subassembly includes a carriage and a carriage drive system for effecting travel of the carriage along a second path, generally laterally along the bridge member.

Abstract: An autonomous assembly is described herein that includes a gantry subassembly, a carrier subassembly movably mounted on the gantry subassembly, a tool actuation subassembly mounted on the carrier subassembly, and an autonomous control system including a perception subsystem, a motion planning subsystem, and a motion control subsystem. The gantry subassembly includes a bridge member for laterally spanning a selected section of a work site and a gantry drive system for effecting travel of the gantry subassembly along a first path, generally in a longitudinally along the length of the selected portion of a work site. The carrier subassembly includes a carriage and a carriage drive system for effecting travel of the carriage along a second path, generally laterally along the bridge member.

Abstract: The invention provides a real-time method and computer-implemented system of monitoring animal health comprising sensing at least one physical characteristic by means of an active physical sensor attached to the animal, and sensing at least one activity of the animal by means of an activity sensor attached to the animal; positioning an active activity signal generator in the environment, such that the activity signal generator is associated with an activity, gathering physical characteristic data and activity data, and wirelessly transmitting all such data to a network receiver/converter, in real-time; converting all such data if necessary, and transmitting all such data over a computer network to one or more users, in real-time.

Abstract: A compound of the formula (1) or a pharmaceutically-acceptable salt, or pro-drug thereof; wherein, for example, Z is CH or nitrogen, R4 and R5 together are either —S—C(R6)?C(R7)— or —C(R7)?C(R6)—S—; R6 and R7 are independently selected from hydrogen, halo, nitro, cyano, hydroxy, fluoromethyl, difluoromethyl, trifluoromethyl, trifluoromethoxy, carboxy and carbamoyl; A is phenylene or heteroarylene; n is 0, 1 or 2; r is 1 or 2; R1 is halo, cyano or carboxy; Y is selected from —C(O)R2, —C(O)OR2, —C(O)NR2R3, -(1-4C)alkyl [optionally substituted] -(2-4C)alkenyl, —SO2NR2R3, and —S(O)cR2 (wherein c is 0, 1 or 2); R2 and R3 are independently selected from hydrogen, —O(1-4C)alkyl, —S(1-4C)alkyl, —N(1-4C)alkyl, heterocyclyl, aryl, and (1-4C)alkyl [optionally substituted]; possess glycogen phosphorylase inhibitory activity and accordingly have value in the treatment of disease states associated with increased glycogen phosphorylase activity.

Abstract: Apparatus for the fixation of a fractured bone in a body cavity comprising a plate and a means for holding the plate in position for a period of fixation, wherein the plate is configured such that in use, the plate is positioned supra-mucosally, and wherein the means for holding the plate in position are adapted such that the means can be passed through the mucosa into the fractured bone.

Abstract: A light transmission system and method for a building according to which shading surfaces are provided on the roof of the building for preventing direct sunlight from passing through a roof light, while permitting the maximum amount of indirect sunlight to pass through the roof light.

Abstract: A display system for displaying samples of wallpaper includes a display stand having a frame and a plurality of display panels, a plurality of wallpaper display samples affixed to the display panels in a pre-selected pattern, a plurality of pre-cut wallpaper take home samples correlated with the display samples and a plurality of containers sized and shaped for removably holding a supply of the take home samples. Each of the containers is mounted onto the frame so as to be located proximate to one of the display samples so as to visually associate the supply of the take home samples with the display sample correlated therewith. The display stand may include a frame rotatably mounted on a base, and upstanding members extending upwardly from the base and outwardly from a notional central axis at 90° angles to each other.

Abstract: A display system for displaying samples of wallpaper includes a display stand having a frame and at least one panel, a plurality of wallpaper display samples affixed to the at least one panel in a pre-selected pattern, a plurality of pre-cut wallpaper samples correlated with the display samples and a plurality of containers sized and shaped for removably holding the pre-cut samples. The pre-cut samples are sized to be substantially smaller than the display samples, and each of the containers is secured to the at least one panel in front of a pre-selected portion of one of the display samples so that a significant portion of the display sample is exposed for visual and tactile examination. The display stand may include four upstanding members which are arranged at approximately ninety-degree intervals about a notional central axis and which project outwardly from that axis, and which each have at least two substantially oppositely faced mounting surfaces on which wallpaper samples may be displayed.

Abstract: An article sorting apparatus and method is disclosed and which conveys a mixture of articles on a conveyor belt and through an inspection zone, and which includes at least one illumination source emitting red, green, and infrared radiation for illuminating the articles in the inspection zone; a detector system for sensing the red, green, and infrared radiation reflected from the articles in the inspection zone, and which generates red data, green data, and infrared data; a processor receiving the red data, green data, and infrared data and which generates article sorting data; and a sorter responsive to the sorting data for separating the articles into acceptable articles and unacceptable articles.

Abstract: A light transmission system and method for a building according to which shading surfaces are provided on the roof of the building for preventing direct sunlight from passing through a roof light, while permitting the maximum amount of indirect sunlight to pass through the roof light.

Abstract: The invention features a control system for controlling the supply of bodyfeed to a filter for removing solids from a beer stream is described. By applying the bodyfeed at an appropriate rate and hence achieving appropriate effective bed voidage it is possible to maintain beer clarity while minimizing filter aid usage. The control system includes a means for determining turbidity of the liquid stream upstream of the filter, a means for determining the rate of pressure drop change across the filter, and a controller for altering the supply of bodyfeed to the filter in accordance with a calculated dose change.

Abstract: A method and apparatus determines continuously mean cardiac output by measuring the arterial pressure e.g. at a finger and calculating therefrom the mean arterial pressure and the time constant of the arterial system (in diastole). Compliance values are provided from a table. Mean cardiac output is then the product of mean arterial pressure and compliance divided by the time constant. Changes in cardiac output can be used for diagnostic purposes. A pressure cuff or pressure tonometer can be used to measure the arterial pressure with a microcomputer providing the necessary calculations.

Abstract: The invention provides a unitary orthotic insert for a shoe that comprises a cupped heel portion having a concave upper bearing surface and a midfoot portion having a medial longitudinal arch support with a curvilinear upper bearing surface. The cupped heel portion extends above a most posterior cephalad portion of a calcaneus and is continuously coupled to the midfoot portion.

Abstract: A system and method of operation performing automated optical inspection to remove peel-bearing defective potato pieces from a random mixture of peel-bearing defective and acceptable potato pieces use near infrared light as a source of illumination. The system implements a method of illuminating the mixture with near infrared light, detecting light reflected by the potato pieces under inspection, identifying defective potato piece surface regions based on the detected reflections, and removing the defective items from the mixture. The system and method the system implements permit the inspection of peel-bearing potato pieces for the presence of peel covered and exposed defects.

Abstract: A system and method of operation performing automated optical inspection to remove peel-bearing defective potato pieces from a random mixture of peel-bearing defective and acceptable potato pieces use near infrared light as a source of illumination. The system implements a method of illuminating the mixture with near infrared light, detecting light reflected by the potato pieces under inspection, identifying defective potato piece surface regions based on the detected reflections, and removing the defective items from the mixture. The system and method the system implements permit the inspection of peel bearing potato pieces for the presence of peel covered defects.

Abstract: Fruit defects of interest in the production of prunes are identified based on characteristics of illumination reflected by the fruit. Various reflection characteristics can be used in this regard including near infrared reflectivity and polarization state of the reflected illumination. In one embodiment, the apparatus (10) of the present invention includes a transport system (12) for transporting fruit (14) through an inspection zone (16), an illumination system (18) for illuminating the fruit (14), a detector system (20) for detecting reflected illumination (21), a sorting system (22) for separating defective fruit from good fruit, and a control system (24) for controlling operation of the sorting system (22) based on signals from the detector system (20) and transport system (12). The signals from the detector system can be improved by treating the fruit inorder to diminish the chlorophyll response.

Abstract: A method of separating selected fruit from a volume of fruit is based on the reflectivity of the selected fruit. The method utilizes an automated optical inspection and sorting system to illuminate a volume of fruit including cranberries characterized by a spectral power distribution in the infrared spectral region. The system detects reflections of wavelengths of the illumination in the infrared spectral region, identifies the selected fruit based on the detected reflectivity, and sorts the selected fruit from the volume of fruit.

Abstract: On method of sensing a ventilation failure measures a ventilation cycle and if the pressure is not maintained throughout the whole of an inspiration period above the setting for the low datum point 10 an alarm is signaled. A normal ventilation cycle is shown in FIG. 1(a) with the pressure over the ventilation cycle indicated by curve 14, low pressure datum 10 and the high pressure datum 12. The inspiration period 16 occurs for a given length of the cycle 14. When the tube feeding air to the patient is disconnected (whether wholly or partially) the ventilation cycle is as shown in FIG. 1(b). Inspiration peak 18 is now much lower and pressure drops rapidly, once the given volume has been delivered, from peak 18 to below set low pressure datum 10 (before termination of period 16). The peak 18 and the slope of the curve as indicated at 20 will vary depending upon the circumstances experienced. Another method measures the period between excursions of the pressure above a given level above datum 10.