Abstract: One embodiment of the present invention provides a system for accommodating time-division multiplexing (TDM) traffic in an Ethernet passive optical network (EPON). During operation, the system receives data from an upstream TDM channel at a remote node and stores received data in a segmentation buffer. The system encapsulates the data stored in the segmentation buffer into a packet. The system receives a message from the central node granting a TDM transmission window starting at a designated time. The system further communicates the packet to an upstream transmission mechanism within the remote node before the designated time, and transmits to the central node an upstream frame containing the packet at the designated time.

Abstract: The present invention relates to novel heterocyclic compounds having the general formula (1) ##STR1## geometric and optical isomers and racemates thereof where such isomers exist, as well as pharmaceutically acceptable acid addition salts thereof and solvates thereof;having therapeutic activity, processes and intermediates for their preparation, pharmaceutical formulations containing said compounds and the medicinal use of said compounds.