Patents by Inventor Duncan BROWMAN

Duncan BROWMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY CONSTRUCTS BINDING 4-1BB AND TUMOR-ASSOCIATED ANTIGENS AND USES THEREOF
    Publication number: 20230052369
    Abstract: Described herein are antibody constructs comprising a 41-1BB binding domain and an antigen-binding domain that binds to a tumor-associated antigen (TAA), wherein the 4-1BB-binding domain and the TAA antigen-binding domain are linked directly or indirectly to a scaffold. The scaffold may be an Fc construct with modifications that reduce its ability to mediate effector function.
    Type: Application
    Filed: April 9, 2021
    Publication date: February 16, 2023
    Inventors: Daniel T. PATTON, David M. MILLS, Thomas SPRETER VON KREUDENSTEIN, Gesa VOLKERS, Dunja UROSEV, Lee FREIBURGER, Zhuang DUAN, Elizabeth HALVORSEN, Harsh PRATAP, Brandon CLAVETTE, Anna VON ROSSUM, Duncan BROWMAN, Peter Wing Yiu CHAN, Danny CHUI, Robert William GENE, Sylwia JANCOWSKI, Sukhbir Singh KANG, Patricia ZWIERZCHOWSKI