Patents by Inventor Duncan M. Smith

Duncan M. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7115607
    Abstract: Selected substituted piperazine compounds of Formula I are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: October 3, 2006
    Assignee: Amgen Inc.
    Inventors: Christopher H. Fotsch, Premilla Arasasingham, Yunxin Bo, Ning Chen, Martin H. Goldberg, Nianhe Han, Feng-Yin Hsieh, Michael G. Kelly, Qingyian Liu, Mark H. Norman, Duncan M. Smith, Markian Stec, Nuria Tamayo, Ning Xi, Shimin Xu
  • Patent number: 6977264
    Abstract: Selected substituted piperidine compounds are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: December 20, 2005
    Assignee: Amgen Inc.
    Inventors: Christopher H. Fotsch, Michael Croghan, Elizabeth M. Doherty, Michael G. Kelly, Mark H. Norman, Duncan M. Smith, Nuria Tamayo, Ning Xi, Shimin Xu
  • Publication number: 20040006067
    Abstract: Selected substituted piperidine compounds are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: July 24, 2002
    Publication date: January 8, 2004
    Inventors: Christopher H. Fotsch, Michael Croghan, Elizabeth M. Doherty, Michael G. Kelly, Mark H. Norman, Duncan M. Smith, Nuria Tamayo, Ning Xi, Shimin Xu
  • Publication number: 20030220324
    Abstract: Selected substituted piperazine compounds are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: July 24, 2002
    Publication date: November 27, 2003
    Inventors: Christopher H. Fotsch, Premilla Arasasingham, Yunxin Bo, Ning Chen, Martin H. Goldberg, Nianhe Han, Feng-Yin Hsieh, Michael G. Kelly, Qingyian Liu, Mark H. Norman, Duncan M. Smith, Markian Stec, Nuria Tamayo, Ning Xi, Shimin Xu
  • Patent number: 6072371
    Abstract: A quenchable VCO that is adapted to be used in switched band synthesizer applications. The VCO may be formed from a heterojunction bipolar transistor (HBT) in a common collector configuration. A quenching circuit which includes a p-i-n diode, is electrically coupled in series with the collector of the HBT. The p-i-n diode is adapted to be monolithically integrated with the HBT. Since the p-i-n diode is electrically connected to the collector of the HBT, as opposed to the base and emitter terminals of the HBT, which forms the main oscillator feedback loop, the Q-factor of the p-i-n diode will have relatively less loading on the phase noise of the HBT oscillator. Moreover, since the p-i-n diode is isolated from the base-emitter junction, the configuration will result in reduced frequency pulling and generation of spurious oscillation and transient effects due to the switching of the p-i-n diode quenched circuit.
    Type: Grant
    Filed: June 16, 1997
    Date of Patent: June 6, 2000
    Assignee: TRW Inc.
    Inventors: Kevin W. Kobayashi, Duncan M. Smith, Aaron K. Oki, Arvind K. Sharma, Barry R. Allen
  • Patent number: 5995818
    Abstract: A small elliptic high pass filter is incorporated into a low noise block downconverter (LNB) to reject image frequencies in a 12 GHz Direct home satellite television Broadcasting System (DBS). A waveguide transition with separate electric probes receives Ku-band satellite signals and transmits the signals to low noise amplifiers (LNAs), a power combiner, an elliptic high pass filter, and a HEMT MMIC receiver. Within the HEMT MMIC receiver, the signal is passed through an RF amplifier stage. A mixer mixes the signal from the RF amplifier stage with a local oscillator signal to produce an intermediate frequency (IF). An IF amplifier stage amplifies the IF signal which is further processed by a television decoder box. Due to the unique response of the elliptic high pass filter, the elliptic high pass filter provides a superior image rejection with lower insertion loss for the LNB, and therefore provides improved television reception quality.
    Type: Grant
    Filed: July 30, 1996
    Date of Patent: November 30, 1999
    Assignee: TRW Inc.
    Inventor: Duncan M. Smith
  • Patent number: 5541565
    Abstract: An enclosure assembly for a high frequency integrated circuit. The enclosure assembly includes a plurality of lead terminals that are part of a lead frame. The lead terminals are connected to electrical ports of the circuit within the enclosure to connect the circuit to other integrated circuits and/or to a printed circuit board. A portion of the lead terminals outside of the enclosure has a specially shaped flared region that establishes the characteristic impedance of the circuit on the lead lines outside of the enclosure.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: July 30, 1996
    Assignee: TRW Inc.
    Inventors: John E. Dowsing, III, Jeffrey M. Edwards, Duncan M. Smith
  • Patent number: 5231361
    Abstract: The present invention resides in a push-push voltage controlled oscillator (VCO) utilizing parallel LC resonant tank circuits for improved phase noise characteristics. The push-push VCO of the present invention includes two voltage controlled oscillators connected in parallel and in phase opposition, with each oscillator including a transistor connected in series with the parallel LC resonant tank circuit. The oscillators operate at the same resonant frequency f.sub.0, but are 180 degrees out of phase. Therefore, the fundamental and odd harmonics of the resonant frequency f.sub.0 cancel each other out and the even harmonics add together to produce an output signal at twice the resonant frequency f.sub.0.
    Type: Grant
    Filed: February 5, 1990
    Date of Patent: July 27, 1993
    Assignee: TRW Inc.
    Inventors: Duncan M. Smith, Barry R. Allen