Patents by Inventor Duncan McVey

Duncan McVey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AFFENADENOVIRUS (GORILLA) OR ADENOVIRAL VECTORS AND METHODS OF USE
    Publication number: 20180066281
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Application
    Filed: July 14, 2017
    Publication date: March 8, 2018
    Applicant: GenVec, Inc.
    Inventors: Jason G.D. Gall, Duncan McVey, Douglas E. Brough
  • Malaria antigens and methods of use
    Patent number: 9833502
    Abstract: The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: December 5, 2017
    Assignee: GenVec, Inc.
    Inventors: Ping Chen, Duncan McVey, Douglas Brough, Joseph Bruder
  • AFFENADENOVIRUS (GORILLA) OR ADENOVIRAL VECTORS AND METHODS OF USE
    Publication number: 20170246318
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Application
    Filed: April 20, 2017
    Publication date: August 31, 2017
    Applicant: GenVec, Inc.
    Inventors: Duncan McVey, Douglas E. Brough, Jason G.D. Gall
  • Affenadenovirus (gorilla) or adenoviral vectors and methods of use
    Patent number: 9725738
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: August 8, 2017
    Assignee: GenVec, Inc.
    Inventors: Jason G. D. Gall, Duncan McVey, Douglas E. Brough
  • RECOMBINANT ADENOVIRUS VECTORED FMDV VACCINES AND USES THEREOF
    Publication number: 20170216422
    Abstract: The present invention encompasses FMDV vaccines or compositions. The invention encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV.
    Type: Application
    Filed: January 30, 2017
    Publication date: August 3, 2017
    Applicants: MERIAL INC., Genvec Inc., THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary of Homeland Security
    Inventors: Justin Widener, Leszlie Woodyward, Leonardo Siger, Douglas Brough, Damodar Ettyreddy, Jason Gall, Duncan McVey, Tom Burrage
  • SIMIAN (GORILLA) ADENOVIRUS OR ADENOVIRAL VECTORS AND METHODS OF USE
    Publication number: 20170211097
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Application
    Filed: April 10, 2017
    Publication date: July 27, 2017
    Applicant: GenVec, Inc.
    Inventors: Douglas E. Brough, Jason G.D. Gall, Duncan McVey
  • Affenadenovirus (gorilla) or adenoviral vectors and methods of use
    Patent number: 9629906
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: April 25, 2017
    Assignee: GenVec, Inc.
    Inventors: Duncan McVey, Douglas E. Brough, Jason G. D. Gall
  • Simian (gorilla) adenovirus or adenoviral vectors and methods of use
    Patent number: 9617560
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: April 11, 2017
    Assignee: GenVec, Inc.
    Inventors: Douglas E. Brough, Jason G. D. Gall, Duncan McVey
  • Methods of propagating monkey adenoviral vectors
    Patent number: 9586998
    Abstract: The invention provides methods for propagating a monkey adenovirus in a cell, including a human cell, comprising one or more gene products isolated from a human adenovirus. Also provided are methods for propagating wherein the monkey adenovirus comprises a nucleic acid sequence encoding a human adenovirus gene product. The invention further provides a monkey adenovirus, including a replication-deficient monkey adenovirus, obtained by such propagation methods.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: March 7, 2017
    Assignee: GenVec, Inc.
    Inventors: Jason Gall, Douglas Brough, Christoph Kahl, Duncan McVey
  • Adenoviral vector-based respiratory syncytial virus (RSV) vaccine
    Patent number: 9580476
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising a nucleic acid sequence encoding one or more Respiratory Syncytial Virus (RSV) antigens and one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein, as well as a method of inducing an immune response against RSV in a mammal by administering the adenovirus or adenoviral vector to the mammal.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: February 28, 2017
    Assignee: GenVec, Inc.
    Inventors: Douglas E. Brough, Jason G. D. Gall, Duncan McVey
  • AFFENADENOVIRUS (GORILLA) OR ADENOVIRAL VECTORS AND METHODS OF USE
    Publication number: 20160122781
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Application
    Filed: January 11, 2016
    Publication date: May 5, 2016
    Applicant: GenVec, Inc.
    Inventors: Jason G.D. Gall, Duncan McVey, Douglas E. Brough
  • Affenadenovirus (gorilla) or adenoviral vectors and methods of use
    Patent number: 9233153
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: January 12, 2016
    Assignee: GenVec, Inc.
    Inventors: Jason G. D. Gall, Duncan McVey, Douglas E. Brough
  • METHODS OF PROPAGATING MONKEY ADENOVIRAL VECTORS
    Publication number: 20150329834
    Abstract: The invention provides methods for propagating a monkey adenovirus in a cell, including a human cell, comprising one or more gene products isolated from a human adenovirus. Also provided are methods for propagating wherein the monkey adenovirus comprises a nucleic acid sequence encoding a human adenovirus gene product. The invention further provides a monkey adenovirus, including a replication-deficient monkey adenovirus, obtained by such propagation methods.
    Type: Application
    Filed: August 4, 2015
    Publication date: November 19, 2015
    Applicant: GenVec, Inc.
    Inventors: Jason Gall, Douglas Brough, Christoph Kahl, Duncan McVey
  • MALARIA ANTIGENS AND METHODS OF USE
    Publication number: 20150297699
    Abstract: The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.
    Type: Application
    Filed: November 12, 2013
    Publication date: October 22, 2015
    Applicant: GENVEC, INC.
    Inventors: Ping Chen, Duncan McVey, Douglas Brough, Joseph Bruder
  • Methods of propagating monkey adenoviral vectors
    Patent number: 9133248
    Abstract: The invention provides methods for propagating a monkey adenovirus in a cell including a human cell, comprising one or more gene products isolated from a human adenovirus. Also provided are methods for propagating wherein the monkey adenovirus comprises a nucleic acid sequence encoding a human adenovirus gene product. The invention further provides a monkey adenovirus. including a replication-deficient monkey adenovirus, obtained by such propagation methods.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: September 15, 2015
    Assignee: GenVec, Inc.
    Inventors: Jason Gall, Douglas Brough, Christoph Kahl, Duncan McVey
  • ADENOVIRAL VECTOR-BASED MALARIA VACCINE
    Publication number: 20150157700
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising a nucleic acid sequence encoding one or more Plasmodium antigens and one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein, as well as a method of inducing an immune response against Plasmodium falciparum in a mammal by administering the adenovirus or adenoviral vector to the mammal.
    Type: Application
    Filed: February 1, 2013
    Publication date: June 11, 2015
    Inventors: Joseph T. Bruder, Jason G.D. Gall, Duncan McVey, Douglas E. Brough
  • Adenoviral vector-based dengue fever vaccine
    Patent number: 8920813
    Abstract: The invention relates to a replication-deficient adenoviral vector comprising two or more nucleic acid sequences encoding Dengue virus antigens and a chimeric hexon protein. The chimeric hexon protein comprises a first portion and a second portion. The first portion comprises at least 10 contiguous amino acid residues from a first adenovirus serotype (e.g., serotype 5 adenovirus hexon protein), optionally with one amino acid substitution. The second portion comprises (a) at least one hypervariable region (HVR) of a hexon protein of an adenovirus of a second adenovirus serotype, or (b) at least one synthetic hypervariable region (HVR) that is not present in the hexon protein of the wild-type adenovirus of the first adenovirus serotype.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: December 30, 2014
    Assignee: GenVec, Inc.
    Inventors: Joseph T. Bruder, Duncan McVey, Douglas E. Brough
  • SIMIAN (GORILLA) ADENOVIRUS OR ADENOVIRAL VECTORS AND METHODS OF USE
    Publication number: 20140314717
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Application
    Filed: October 5, 2012
    Publication date: October 23, 2014
    Inventors: Douglas E. Brough, Jason G.D. Gall, Duncan McVey
  • ADENOVIRAL VECTOR-BASED RESPIRATORY SYNCYTIAL VIRUS (RSV) VACCINE
    Publication number: 20140271711
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising a nucleic acid sequence encoding one or more Respiratory Syncytial Virus (RSV) antigens and one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein, as well as a method of inducing an immune response against RSV in a mammal by administering the adenovirus or adenoviral vector to the mammal.
    Type: Application
    Filed: October 5, 2012
    Publication date: September 18, 2014
    Inventors: Douglas E. Brough, Jason G.D. Gall, Duncan McVey
  • AFFENADENOVIRUS (GORILLA) OR ADENOVIRAL VECTORS AND METHODS OF USE
    Publication number: 20140248308
    Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
    Type: Application
    Filed: October 5, 2012
    Publication date: September 4, 2014
    Inventors: Duncan McVey, Douglas E. Brough, Jason G.D. Gall