Abstract: The invention concerns novel pharmaceutical compositions comprising 2, 4, 4?-trichloro-2?-hydroxydiphenylether (triclosan) and a thickener for use in the treatment of chronic wounds, in particular, in treatment of diabetic chronic wounds, such as foot ulcers.

Abstract: The invention relates to methods of preparation of highly sensitive potentiometric sensors with an electroconductive polymer film as a sensing element.

Abstract: A method of electrochemical analysis using a sensor electrode specific for an analyte under test. The method comprises immersing the sensor electrode in a sample solution suspected of containing the analyte; forming an electrochemically active complex by exposure to solutions containing secondary receptors or competing molecules labelled with a charged or enzyme label; and subsequently exposing the sensor to an electrochemically active solution. The measurement step comprises driving the sensor electrode potential to a predetermined fixed potential by applying a current or activation waveform then monitoring the potential difference between the sensor electrode and a reference electrode following removal of the holding current. Current, rate and potential can all be measured and used to determine analyte concentration or sensor state.

Abstract: A method of electrochemical analysis using a sensor electrode specific for an analyte under test. The method comprises immersing the sensor electrode in a sample solution suspected of containing the analyte; forming an electrochemically active complex by exposure to solutions containing secondary receptors or competing molecules labelled with a charged or enzyme label; and subsequently exposing the sensor to an electrochemically active solution. The measurement step comprises driving the sensor electrode potential to a predetermined fixed potential by applying a current or activation waveform then monitoring the potential difference between the sensor electrode and a reference electrode following removal of the holding current. Current, rate and potential can all be measured and used to determine analyte concentration or sensor state.

Abstract: The invention relates to methods of preparation of highly sensitive potentiometric sensors with an electroconductive polymer film as a sensing element.

Abstract: This invention provides methods for denaturing nucleic acids. The methods involve contacting a solution comprising double stranded nucleic acid with a surface having denaturation activity sufficient to produce denaturation within a period of not more than one hour.

Abstract: Perfluorocarbon polymer-based matrices are coated with a hydrophilic polymer for use in bioaffinity separations. Coating is carried out by dispersing porous particles of inert perfluorocarbon polymer in a water-miscible organic solvent such as acetone or tetrafydrofuran to wet surfaces of the particles, forming a dispersion of the wetted particles in an aqueous solution of hydrophilic polymer such as poly(vinyl alcohol) containing a plurality of hydroxyl groups, at least one being at an end of a polymer chain, to adsorb the hydrophilic polymer onto the wetted surfaces of the particles, admixing a homobifunctional cross-linking agent such as glutaraldehyde with the particles to cross-link the hydrophilic polymer, activating hydroxyl groups on the surface of the cross-linked hydrophilic polymer and covalently bonding a ligand or ligand binder to the activated hydroxyl groups.