Patents by Inventor Dung K. Hong

Dung K. Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipophilic contrast agents for use in hepatocyte-selective oil-in-water emulsions
    Patent number: 5654452
    Abstract: Aromatic acid-derived lipophilic polyhalogenated compounds are provided for use as contrast agents in diagnostic imaging or as therapeutic agents. These compounds are particularly useful when incorporated into an oil-in-water emulsion for tissue-specific delivery to the liver. For hepatocyte-selective delivery, the emulsion is chylomicron remnant-like by being in a size range of 50 to 200 nm and having a composition simulating naturally-occuring chylomicron remnants.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 5, 1997
    Assignee: Molecular Biosystems, Inc.
    Inventors: Rolf Lohrmann, Dung K. Hong
  • Emulsions as contrast agents and method of use
    Patent number: 5536489
    Abstract: This invention relates to an oil-in-water emulsion that is of a water-insoluble gas-forming chemical and a stabilizer. The emulsion being capable of forming microbubbles of gas upon application of ultrasonic energy. This composition allows for site specific imaging as the image enhancing microbubbles can be released upon the application of ultrasonic energy at the specific location where the image is desired.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: July 16, 1996
    Assignee: Molecular Biosystems, Inc.
    Inventors: Rolf Lohrmann, Kenneth J. Widder, Ashwin M. Krishnan, Dung K. Hong, Jialun Meng