Patents by Inventor Dunia Hernández Inguanzo

Dunia Hernández Inguanzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120308615
    Abstract: The present invention is related with the field of the therapeutic immunization, specifically with the employment of a new formulation of antigens of the Hepatitis B Virus (HBV) for the cellular stimulation. The formulation is formed by the surface antigens (HBsAg) precipitated in suspension and the nucleocapsid (HBcAg) of the HBV. The formulation contains these antigens like suspended particles of sizes less than 500 nm and higher than 500 nm, in a mixture where the proportion among the particles of the mentioned sizes is among 50%-50% and 80%-20%, respectively. The selection of a range of sizes of particles allows that the levels of stimulation of several cellular types are maximized. Additionally, a cellular stimulation method is described with this formulation, and the later passive immunization of patients with chronic Hepatitis B, based on the maximum stimulation in vivo or in vitro using heterologous or autologous cells (dendritic cells, B cells and macrophages).
    Type: Application
    Filed: September 28, 2010
    Publication date: December 6, 2012
    Inventors: Julio César Aguilar Rubido, Yadira Lobaina Mato, Dunia Hernández Inguanzo, Heidy Trujillo Pérez, Freya de los Milagros Freyre Almeida, Verena Lucila Muzio González, Eduardo Pénton Arias, Sonia Gonzalez Blanco, Raimundo Ubieta Gómez, Gerardo Enrique Guillén Nieto, Luis Saturnino Herrera Martinez