Patents by Inventor Duong P. Huynh

Duong P. Huynh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Parkin interacting polypeptides and methods of use
    Patent number: 8138307
    Abstract: The invention provides parkin binding polypeptides and encoding nucleic acids. The invention also provides antibodies specific for the parkin binding polypeptides. The invention additionally provides methods of detecting a parkin binding polypeptide and detecting a nucleic acid encoding a parkin binding polypeptide. The invention further provides methods of using a parkin binding polypeptide. In one embodiment, the invention provides a method of identifying a candidate drug for treating Parkinson's disease by contacting a parkin binding polypeptide with one or more compounds and identifying a compound that alters the activity of the parkin binding polypeptide.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: March 20, 2012
    Assignee: Cedars-Sinai Medical Center
    Inventors: Stefan M. Pulst, Duong P. Huynh
  • Parkin interacting polypeptides and methods of use
    Patent number: 7927786
    Abstract: The invention provides parkin binding polypeptides and encoding nucleic acids. The invention also provides antibodies specific for the parkin binding polypeptides. The invention additionally provides methods of detecting a parkin binding polypeptide and detecting a nucleic acid encoding a parkin binding polypeptide. The invention further provides methods of using a parkin binding polypeptide. In one embodiment, the invention provides a method of identifying a candidate drug for treating Parkinson's disease by contacting a parkin binding polypeptide with one or more compounds and identifying a compound that alters the activity of the parkin binding polypeptide.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: April 19, 2011
    Assignee: Cedars-Sinai Medical Center
    Inventors: Stefan M. Pulst, Duong P. Huynh
  • Parkin interacting polypeptides and methods of use
    Publication number: 20080301824
    Abstract: The invention provides parkin binding polypeptides and encoding nucleic acids. The invention also provides antibodies specific for the parkin binding polypeptides. The invention additionally provides methods of detecting a parkin binding polypeptide and detecting a nucleic acid encoding a parkin binding polypeptide. The invention further provides methods of using a parkin binding polypeptide. In one embodiment, the invention provides a method of identifying a candidate drug for treating Parkinson's disease by contacting a parkin binding polypeptide with one or more compounds and identifying a compound that alters the activity of the parkin binding polypeptide.
    Type: Application
    Filed: February 18, 2004
    Publication date: December 4, 2008
    Inventors: Stefan M. Pulst, Duong P. Huynh
  • Transgenic mouse expressing a polynucleotide encoding a human ataxin-2 polypeptide
    Patent number: 6515197
    Abstract: The invention provides a transgenic non-human mammal comprising nucleated cells containing a transgene encoding an ataxin-2 polypeptide comprising a polyglutamine tract. In particular, the transgenic-non-human mammal can be a mouse. The invention also provides methods of using a transgenic non-human mammal expressing SCA2 encoding an ataxin-2 polypeptide to identify a therapeutic agent for use in treating a neurodegenerative disease by administering a compound to a transgenic non-human mammal expressing SCA2 encoding an ataxin-2 polypeptide and screening the transgenic non-human mammal for an improved neurological response associated with a neurodegenerative phenotype of the transgenic non-human mammal, thereby identifying a therapeutic agent for use in treating the neurodegenerative disease.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: February 4, 2003
    Assignee: Cedars-Sinai Medical Center
    Inventors: Stefan M. Pulst, Duong P. Huynh