Patents by Inventor Dushan M. Dvornik

Dushan M. Dvornik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aldose reductase inhibition by 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
    Patent number: 4442118
    Abstract: Disclosed are new methods of using 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.
    Type: Grant
    Filed: July 23, 1981
    Date of Patent: April 10, 1984
    Assignee: Ayerst, McKenna & Harrison, Inc.
    Inventors: Dushan M. Dvornik, Nicole Simard-Duquesne
  • Aldose reductase inhibition by 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-ac etic acid
    Patent number: 4423075
    Abstract: Disclosed are new methods of using 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acet ic acid or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: December 27, 1983
    Assignee: Ayerst, McKenna & Harrison Inc.
    Inventors: Dushan M. Dvornik, Nicole Simard-Duquesne
  • Aldose reductase inhibition by 1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid
    Patent number: 4423060
    Abstract: Disclosed are new methods of using 1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.
    Type: Grant
    Filed: August 17, 1981
    Date of Patent: December 27, 1983
    Assignee: Ayerst, McKenna & Harrison Inc.
    Inventors: Dushan M. Dvornik, Nicole Simard-Duquesne
  • Aldose reductase inhibition by 5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]me]-1H-indene-3-acetic acid
    Patent number: 4423074
    Abstract: Disclosed are new methods of using 5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: December 27, 1983
    Assignee: Ayerst, McKenna & Harrison Inc.
    Inventors: Dushan M. Dvornik, Nicole Simard-Duquesne
  • Aldose reductase inhibition by .gamma.-oxo-8-fluoranthenebutanoic acid
    Patent number: 4361582
    Abstract: Disclosed are new methods of using .gamma.-oxo-8-fluoranthenebutanoic acid, or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.
    Type: Grant
    Filed: August 17, 1981
    Date of Patent: November 30, 1982
    Assignee: Ayerst, McKenna & Harrison Inc.
    Inventors: Dushan M. Dvornik, Nicole Simard-Duquesne
  • Aldose reductase inhibition by (Z)-5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene- 3-acetic acid
    Patent number: 4307114
    Abstract: Disclosed are new methods of using (Z)-5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3- acetic acid or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.
    Type: Grant
    Filed: June 19, 1980
    Date of Patent: December 22, 1981
    Assignee: Ayerst, McKenna & Harrison, Inc.
    Inventors: Dushan M. Dvornik, Nicole Simard-Duquesne