Patents by Inventor Dustin Harshman

Dustin Harshman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM LEVEL CALIBRATION
    Publication number: 20230375477
    Abstract: Disclosed herein are systems and methods of calibrating a microscope or an imaging system prior to acquiring image data of a sample. In some embodiments, a method is disclosed including the steps of (a) running a power output calibration module to calibrate an imaging apparatus for repeatability; (b) running an image intensity calibration module to calibrate the imaging apparatus for reproducibility and to mitigate differences in detection efficiency between channels; (c) collecting image data from a microscope or imaging system; (d) optionally running an unmixing module to unmix the collected image data into individual image channel images; and (e) optionally running a contrast agent intensity correction module to calibrate for differences in brightness between different contrast agents.
    Type: Application
    Filed: August 4, 2023
    Publication date: November 23, 2023
    Inventors: Karl Garsha, Dustin Harshman
  • Interfacial effects enable droplet actuation, inhibition relief, and early sensing of polymerase chain reaction
    Patent number: 10760119
    Abstract: Disclosed are devices, systems and methods of use utilizing interfacial effects enabling droplet actuation, inhibition and early sensing of molecular reactions, such as of polymerase chain reaction.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: September 1, 2020
    Assignee: Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Jeong-Yeol Yoon, Dustin Harshman
  • SYSTEM LEVEL CALIBRATION
    Publication number: 20200080940
    Abstract: Disclosed herein are systems and methods of calibrating a microscope or an imaging system prior to acquiring image data of a sample. In some embodiments, a method is disclosed including the steps of (a) running a power output calibration module to calibrate an imaging apparatus for repeatability; (b) running an image intensity calibration module to calibrate the imaging apparatus for reproducibility and to mitigate differences in detection efficiency between channels; (c) collecting image data from a microscope or imaging system; (d) optionally running an unmixing module to unmix the collected image data into individual image channel images; and (e) optionally running a contrast agent intensity correction module to calibrate for differences in brightness between different contrast agents.
    Type: Application
    Filed: November 11, 2019
    Publication date: March 12, 2020
    Inventors: Karl Garsha, Dustin Harshman
  • INTERFACIAL EFFECTS ENABLE DROPLET ACTUATION, INHIBITION RELIEF, AND EARLY SENSING OF POLYMERASE CHAIN REACTION
    Publication number: 20170298416
    Abstract: Disclosed are devices, systems and methods of use utilizing interfacial effects enabling droplet actuation, inhibition and early sensing of molecular reactions, such as of polymerase chain reaction.
    Type: Application
    Filed: October 23, 2015
    Publication date: October 19, 2017
    Applicant: Arizona Board of Regents on behalf of the Universi ty of Arizona
    Inventors: Jeong-Yeol Yoon, Dustin Harshman