Patents by Inventor Dustin J. KREFT
Dustin J. KREFT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12148603Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.Type: GrantFiled: March 2, 2022Date of Patent: November 19, 2024Assignee: Thermo Finnigan LLCInventors: Scott T. Quarmby, Giacinto Zilioli, Charles H. Vogt, Dustin J. Kreft, Nathaniel L. Sanders, George B. Guckenberger, John G. Voss
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Patent number: 11942315Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.Type: GrantFiled: March 3, 2022Date of Patent: March 26, 2024Assignee: Thermo Finnigan LLCInventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
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Patent number: 11754062Abstract: A method comprises: heating a flow of coolant liquid by passing the flow through one or more fluidic tubing lines, channels or conduits that are in thermal contact with a housing of a vacuum pump; apportioning the flow of heated coolant liquid between a bypass fluid tubing line and a channel within a wall of a vacuum chamber; recombining the first and second partial flows of the heated coolant liquid; passing the recombined flow of the coolant liquid through a heat exchanger that cools the coolant liquid; and recirculating the cooled coolant liquid through the one or more fluidic tubing lines, channels or conduits that are in thermal contact with the vacuum pump housing, wherein the apportionment of the flow of the heated coolant liquid is automatically performed under the control of an electronic controller or computer in response to a temperature measurement received by the electronic controller or computer.Type: GrantFiled: March 21, 2022Date of Patent: September 12, 2023Assignee: THERMO FINNIGAN LLCInventors: Jaime A. Carrera, Dustin J. Kreft
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Publication number: 20230005728Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.Type: ApplicationFiled: March 3, 2022Publication date: January 5, 2023Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
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Publication number: 20220270867Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.Type: ApplicationFiled: March 2, 2022Publication date: August 25, 2022Inventors: Scott T. QUARMBY, Giacinto ZILIOLI, Charles H. VOGT, Dustin J. KREFT, Nathaniel L. SANDERS, George B. GUCKENBERGER, John G. VOSS
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Publication number: 20220213880Abstract: A method comprises: heating a flow of coolant liquid by passing the flow through one or more fluidic tubing lines, channels or conduits that are in thermal contact with a housing of a vacuum pump; apportioning the flow of heated coolant liquid between a bypass fluid tubing line and a channel within a wall of a vacuum chamber; recombining the first and second partial flows of the heated coolant liquid; passing the recombined flow of the coolant liquid through a heat exchanger that cools the coolant liquid; and recirculating the cooled coolant liquid through the one or more fluidic tubing lines, channels or conduits that are in thermal contact with the vacuum pump housing, wherein the apportionment of the flow of the heated coolant liquid is automatically performed under the control of an electronic controller or computer in response to a temperature measurement received by the electronic controller or computer.Type: ApplicationFiled: March 21, 2022Publication date: July 7, 2022Applicant: Thermo Finnigan LLCInventors: Jaime A. CARRERA, Dustin J. KREFT
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Patent number: 11336290Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole based on an amplifier RF input signal. An analog-to-digital converter (ADC) can generate a digital representation of the RF signal. A controller circuit can receive the digital representation and adjust an amplitude of the amplifier RF input signal based on differences between an amplitude of a fundamental frequency of the RF signal being different than an expected amplitude.Type: GrantFiled: March 30, 2020Date of Patent: May 17, 2022Assignee: Thermo Finnigan LLCInventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
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Patent number: 11293422Abstract: A system comprises: a vacuum chamber disposed within a housing and having a vacuum port; a vacuum pump within the housing and having a gas inlet port that is fluidically coupled to the vacuum port; and a fluid circuit that comprises: one or more fluidic tubing lines, channels or conduits in thermal contact with a housing of the vacuum pump; a liquid pump fluidically coupled to an inlet of the one or more fluidic tubing lines, channels or conduits; and a heat exchanger having a heat exchanger inlet and a heat exchanger outlet, wherein the heat exchanger inlet is fluidically coupled to an outlet of the one or more fluidic tubing lines, channels or conduits and the heat exchanger outlet is fluidically coupled to the liquid pump. The fluid circuit may also include a portion that is in thermal contact with the vacuum chamber.Type: GrantFiled: August 2, 2019Date of Patent: April 5, 2022Assignee: THERMO FINNIGAN LLCInventors: Jaime A. Carrera, Dustin J. Kreft
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Patent number: 11282685Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.Type: GrantFiled: October 11, 2019Date of Patent: March 22, 2022Assignee: THERMO FINNIGAN LLCInventors: Scott T. Quarmby, Giacinto Zilioli, Charles H. Vogt, Dustin J. Kreft, Nathaniel L. Sanders, George B. Guckenberger, John G. Voss
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Patent number: 11270874Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.Type: GrantFiled: March 30, 2020Date of Patent: March 8, 2022Assignee: Thermo Finnigan LLCInventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
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Publication number: 20210305991Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole based on an amplifier RF input signal. An analog-to-digital converter (ADC) can generate a digital representation of the RF signal. A controller circuit can receive the digital representation and adjust an amplitude of the amplifier RF input signal based on differences between an amplitude of a fundamental frequency of the RF signal being different than an expected amplitude.Type: ApplicationFiled: March 30, 2020Publication date: September 30, 2021Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
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Publication number: 20210305035Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.Type: ApplicationFiled: March 30, 2020Publication date: September 30, 2021Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
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Publication number: 20210111013Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.Type: ApplicationFiled: October 11, 2019Publication date: April 15, 2021Inventors: Scott T. QUARMBY, Giacinto ZILIOLI, Charles H. VOGT, Dustin J. KREFT, Nathaniel L. SANDERS, George B. GUCKENBERGER, John G. VOSS
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Publication number: 20210033086Abstract: A system comprises: a vacuum chamber disposed within a housing and having a vacuum port; a vacuum pump within the housing and having a gas inlet port that is fluidically coupled to the vacuum port; and a fluid circuit that comprises: one or more fluidic tubing lines, channels or conduits in thermal contact with a housing of the vacuum pump; a liquid pump fluidically coupled to an inlet of the one or more fluidic tubing lines, channels or conduits; and a heat exchanger having a heat exchanger inlet and a heat exchanger outlet, wherein the heat exchanger inlet is fluidically coupled to an outlet of the one or more fluidic tubing lines, channels or conduits and the heat exchanger outlet is fluidically coupled to the liquid pump. The fluid circuit may also include a portion that is in thermal contact with the vacuum chamber.Type: ApplicationFiled: August 2, 2019Publication date: February 4, 2021Inventors: Jaime A. CARRERA, Dustin J. KREFT