Patents by Inventor Dustin J. KREFT

Dustin J. KREFT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12148603
    Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.
    Type: Grant
    Filed: March 2, 2022
    Date of Patent: November 19, 2024
    Assignee: Thermo Finnigan LLC
    Inventors: Scott T. Quarmby, Giacinto Zilioli, Charles H. Vogt, Dustin J. Kreft, Nathaniel L. Sanders, George B. Guckenberger, John G. Voss
  • Patent number: 11942315
    Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.
    Type: Grant
    Filed: March 3, 2022
    Date of Patent: March 26, 2024
    Assignee: Thermo Finnigan LLC
    Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
  • Patent number: 11754062
    Abstract: A method comprises: heating a flow of coolant liquid by passing the flow through one or more fluidic tubing lines, channels or conduits that are in thermal contact with a housing of a vacuum pump; apportioning the flow of heated coolant liquid between a bypass fluid tubing line and a channel within a wall of a vacuum chamber; recombining the first and second partial flows of the heated coolant liquid; passing the recombined flow of the coolant liquid through a heat exchanger that cools the coolant liquid; and recirculating the cooled coolant liquid through the one or more fluidic tubing lines, channels or conduits that are in thermal contact with the vacuum pump housing, wherein the apportionment of the flow of the heated coolant liquid is automatically performed under the control of an electronic controller or computer in response to a temperature measurement received by the electronic controller or computer.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: September 12, 2023
    Assignee: THERMO FINNIGAN LLC
    Inventors: Jaime A. Carrera, Dustin J. Kreft
  • Publication number: 20230005728
    Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.
    Type: Application
    Filed: March 3, 2022
    Publication date: January 5, 2023
    Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
  • Publication number: 20220270867
    Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.
    Type: Application
    Filed: March 2, 2022
    Publication date: August 25, 2022
    Inventors: Scott T. QUARMBY, Giacinto ZILIOLI, Charles H. VOGT, Dustin J. KREFT, Nathaniel L. SANDERS, George B. GUCKENBERGER, John G. VOSS
  • Publication number: 20220213880
    Abstract: A method comprises: heating a flow of coolant liquid by passing the flow through one or more fluidic tubing lines, channels or conduits that are in thermal contact with a housing of a vacuum pump; apportioning the flow of heated coolant liquid between a bypass fluid tubing line and a channel within a wall of a vacuum chamber; recombining the first and second partial flows of the heated coolant liquid; passing the recombined flow of the coolant liquid through a heat exchanger that cools the coolant liquid; and recirculating the cooled coolant liquid through the one or more fluidic tubing lines, channels or conduits that are in thermal contact with the vacuum pump housing, wherein the apportionment of the flow of the heated coolant liquid is automatically performed under the control of an electronic controller or computer in response to a temperature measurement received by the electronic controller or computer.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Applicant: Thermo Finnigan LLC
    Inventors: Jaime A. CARRERA, Dustin J. KREFT
  • Patent number: 11336290
    Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole based on an amplifier RF input signal. An analog-to-digital converter (ADC) can generate a digital representation of the RF signal. A controller circuit can receive the digital representation and adjust an amplitude of the amplifier RF input signal based on differences between an amplitude of a fundamental frequency of the RF signal being different than an expected amplitude.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: May 17, 2022
    Assignee: Thermo Finnigan LLC
    Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
  • Patent number: 11293422
    Abstract: A system comprises: a vacuum chamber disposed within a housing and having a vacuum port; a vacuum pump within the housing and having a gas inlet port that is fluidically coupled to the vacuum port; and a fluid circuit that comprises: one or more fluidic tubing lines, channels or conduits in thermal contact with a housing of the vacuum pump; a liquid pump fluidically coupled to an inlet of the one or more fluidic tubing lines, channels or conduits; and a heat exchanger having a heat exchanger inlet and a heat exchanger outlet, wherein the heat exchanger inlet is fluidically coupled to an outlet of the one or more fluidic tubing lines, channels or conduits and the heat exchanger outlet is fluidically coupled to the liquid pump. The fluid circuit may also include a portion that is in thermal contact with the vacuum chamber.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: April 5, 2022
    Assignee: THERMO FINNIGAN LLC
    Inventors: Jaime A. Carrera, Dustin J. Kreft
  • Patent number: 11282685
    Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: March 22, 2022
    Assignee: THERMO FINNIGAN LLC
    Inventors: Scott T. Quarmby, Giacinto Zilioli, Charles H. Vogt, Dustin J. Kreft, Nathaniel L. Sanders, George B. Guckenberger, John G. Voss
  • Patent number: 11270874
    Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: March 8, 2022
    Assignee: Thermo Finnigan LLC
    Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
  • Publication number: 20210305991
    Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole based on an amplifier RF input signal. An analog-to-digital converter (ADC) can generate a digital representation of the RF signal. A controller circuit can receive the digital representation and adjust an amplitude of the amplifier RF input signal based on differences between an amplitude of a fundamental frequency of the RF signal being different than an expected amplitude.
    Type: Application
    Filed: March 30, 2020
    Publication date: September 30, 2021
    Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
  • Publication number: 20210305035
    Abstract: Control of an amplitude of a signal applied to rods of a quadrupole is described. In one aspect, a mass spectrometer includes an amplifier circuit that causes a radio frequency (RF) signal to be applied to the rods of the quadrupole. A controller circuit can determine that the actual amplitude of the RF signal differs than the expected amplitude and, in response, identify current and past environmental and performance parameters to adjust the amplitude.
    Type: Application
    Filed: March 30, 2020
    Publication date: September 30, 2021
    Inventors: Johnathan W. Smith, Scott T. Quarmby, Dustin J. Kreft, Michael W. Senko
  • Publication number: 20210111013
    Abstract: A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer. The tuning system may determine, based on the tune data, a value of an operating parameter configured to adjust the operating characteristic of the mass spectrometer and set the operating parameter to the determined value.
    Type: Application
    Filed: October 11, 2019
    Publication date: April 15, 2021
    Inventors: Scott T. QUARMBY, Giacinto ZILIOLI, Charles H. VOGT, Dustin J. KREFT, Nathaniel L. SANDERS, George B. GUCKENBERGER, John G. VOSS
  • Publication number: 20210033086
    Abstract: A system comprises: a vacuum chamber disposed within a housing and having a vacuum port; a vacuum pump within the housing and having a gas inlet port that is fluidically coupled to the vacuum port; and a fluid circuit that comprises: one or more fluidic tubing lines, channels or conduits in thermal contact with a housing of the vacuum pump; a liquid pump fluidically coupled to an inlet of the one or more fluidic tubing lines, channels or conduits; and a heat exchanger having a heat exchanger inlet and a heat exchanger outlet, wherein the heat exchanger inlet is fluidically coupled to an outlet of the one or more fluidic tubing lines, channels or conduits and the heat exchanger outlet is fluidically coupled to the liquid pump. The fluid circuit may also include a portion that is in thermal contact with the vacuum chamber.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 4, 2021
    Inventors: Jaime A. CARRERA, Dustin J. KREFT