Patents by Inventor Dustin McMinn

Dustin McMinn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS OF HYDROXYPROPYL-BETA-CYCLODEXTRIN AND METHODS OF PURIFYING THE SAME
    Publication number: 20240409671
    Abstract: The present disclosure relates to compositions comprising mixtures of hydroxypropyl-?-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-?-cyclodextrins.
    Type: Application
    Filed: August 23, 2024
    Publication date: December 12, 2024
    Inventors: Steven Pfeiffer, Dustin McMinn, Gabor Benkovics
  • COMPOSITIONS OF HYDROXYPROPYL-BETA-CYCLODEXTRIN AND METHODS OF PURIFYING THE SAME
    Publication number: 20240287211
    Abstract: The present disclosure relates to compositions comprising mixtures of hydroxypropyl-?-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-?-cyclodextrins.
    Type: Application
    Filed: April 11, 2024
    Publication date: August 29, 2024
    Inventors: Steven Pfeiffer, Dustin McMinn, Gabor Benkovics
  • COMPOSITIONS OF HYDROXYPROPYL-BETA-CYCLODEXTRIN AND METHODS OF PURIFYING THE SAME
    Publication number: 20240270877
    Abstract: The present disclosure relates to compositions comprising mixtures of hydroxypropyl-?-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-?-cyclodextrins.
    Type: Application
    Filed: April 11, 2024
    Publication date: August 15, 2024
    Inventors: Steven Pfeiffer, Dustin McMinn, Gabor Benkovics
  • Process of preparing a peptide epoxyketone immunoproteasome inhibitor, and precursors thereof
    Patent number: 11976053
    Abstract: Disclosed herein are methods for preparing [(2S,3R)—N—[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound “G”): and precursors thereof.
    Type: Grant
    Filed: October 13, 2022
    Date of Patent: May 7, 2024
    Assignee: KEZAR LIFE SCIENCES, INC.
    Inventors: Henry Johnson, Sean Dalziel, Dustin McMinn
  • Compositions of hydroxypropyl-beta-cyclodextrin and methods of purifying the same
    Patent number: 11958917
    Abstract: Compositions comprising mixtures of hydroxypropyl-?-cyclodextrin, wherein the compositions may be isomerically purified, and methods of isomerically purifying a mixture of hydroxypropyl-?-cyclodextrins.
    Type: Grant
    Filed: February 17, 2023
    Date of Patent: April 16, 2024
    Assignee: BEREN THERAPEUTICS P.B.C.
    Inventors: Steven Pfeiffer, Dustin McMinn, Gabor Benkovics
  • COMPOSITIONS OF HYDROXYPROPYL-BETA-CYCLODEXTRIN AND METHODS OF PURIFYING THE SAME
    Publication number: 20240067760
    Abstract: The present disclosure relates to compositions comprising mixtures of hydroxypropyl-?-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-?-cyclodextrins.
    Type: Application
    Filed: October 27, 2023
    Publication date: February 29, 2024
    Inventors: Steven Pfeiffer, Dustin McMinn, Gabor Benkovics
  • Crystalline salts of peptide epoxyketone immunoproteasome inhibitor
    Patent number: 11891383
    Abstract: Provided herein is a peptide epoxyketone immunoproteasome inhibitor, crystal forms, salts, and processes for making the same, and formulations thereof.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: February 6, 2024
    Assignee: KEZAR LIFE SCIENCES
    Inventors: Henry Johnson, Evan Lewis, Sean Dalziel, Dustin McMinn
  • PROTEIN SECRETION INHIBITORS
    Publication number: 20230286973
    Abstract: Provided herein are secretion inhibitors, such as inhibitors of Sec61 for example of Formula (I), methods for their preparation, related pharmaceutical compositions, and method for using the same.
    Type: Application
    Filed: August 31, 2021
    Publication date: September 14, 2023
    Inventors: Dustin McMinn, Meera Rao
  • COMPOSITIONS OF HYDROXYPROPYL-BETA-CYCLODEXTRIN AND METHODS OF PURIFYING THE SAME
    Publication number: 20230265219
    Abstract: The present disclosure relates to compositions comprising mixtures of hydroxypropyl-?-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-?-cyclodextrins.
    Type: Application
    Filed: February 17, 2023
    Publication date: August 24, 2023
    Inventors: Steven Pfeiffer, Dustin McMinn, Gabor Benkovics
  • PROCESS OF PREPARING A PEPTIDE EPOXYKETONE IMMUNOPROTEASOME INHIBITOR, AND PRECURSORS THEREOF
    Publication number: 20230135100
    Abstract: Disclosed herein are methods for preparing [(2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound “G”): and precursors thereof.
    Type: Application
    Filed: October 13, 2022
    Publication date: May 4, 2023
    Inventors: Henry Johnson, Sean Dalziel, Dustin McMinn
  • CRYSTALLINE SALTS OF PEPTIDE EPOXYKETONE IMMUNOPROTEASOME INHIBITOR
    Publication number: 20230106656
    Abstract: Provided herein is a peptide epoxyketone immunoproteasome inhibitor, crystal forms, salts, and processes for making the same, and formulations thereof.
    Type: Application
    Filed: September 27, 2022
    Publication date: April 6, 2023
    Inventors: Henry Johnson, Evan Lewis, Sean Dalziel, Dustin McMinn
  • Process of preparing a peptide epoxyketone immunoproteasome inhibitor, and precursors thereof
    Patent number: 11498907
    Abstract: Disclosed herein are methods for preparing [(2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound “G”): and precursors thereof.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: November 15, 2022
    Assignee: KEZAR LIFE SCIENCES
    Inventors: Henry Johnson, Sean Dalziel, Dustin McMinn
  • Crystalline salts of peptide epoxyketone immunoproteasome inhibitor
    Patent number: 11479548
    Abstract: Provided herein is a peptide epoxyketone immunoproteasome inhibitor, crystal forms, salts, and processes for making the same, and formulations thereof.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: October 25, 2022
    Assignee: KEZAR LIFE SCIENCES
    Inventors: Henry Johnson, Evan Lewis, Sean Dalziel, Dustin McMinn
  • CDP protein secretion inhibitors
    Patent number: 11339193
    Abstract: Provided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and methods of using these inhibitors. The compounds disclosed herein can be used, e.g., for the treatment of cancer, arthritis, and/or inflammation.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: May 24, 2022
    Assignees: KEZAR LIFE SCIENCES, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Dustin McMinn, John William Taunton, Phillip Patrick Sharp
  • PROTEIN SECRETION INHIBITORS
    Publication number: 20220153732
    Abstract: Provided herein are secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same, wherein the compound has a structure of Formula (I), (II), or (III).
    Type: Application
    Filed: February 28, 2020
    Publication date: May 19, 2022
    Inventors: Dustin McMinn, Meera Rao
  • Tripeptide epoxy ketone protease inhibitors
    Patent number: 11078233
    Abstract: Provided herein are tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X): and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of diseases including inflammation and neurodegenerative disease.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: August 3, 2021
    Assignee: Onyx Therapeutics, Inc.
    Inventors: Dustin McMinn, Henry Johnson, Simeon Bowers, David C. Moebius
  • CRYSTALLINE SALTS OF PEPTIDE EPOXYKETONE IMMUNOPROTEASOME INHIBITOR
    Publication number: 20210032232
    Abstract: Provided herein is a peptide epoxyketone immunoproteasome inhibitor, crystal forms, salts, and processes for making the same, and formulations thereof.
    Type: Application
    Filed: October 9, 2020
    Publication date: February 4, 2021
    Inventors: Henry Johnson, Evan Lewis, Sean Dalziel, Dustin McMinn
  • CDP PROTEIN SECRETION INHIBITORS
    Publication number: 20210017233
    Abstract: Provided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and methods of using these inhibitors. The compounds disclosed herein can be used, e.g., for the treatment of cancer, arthritis, and/or inflammation.
    Type: Application
    Filed: March 29, 2019
    Publication date: January 21, 2021
    Inventors: Dustin McMinn, John William Taunton, Phillip Patrick Sharp
  • PROCESS OF PREPARING A PEPTIDE EPOXYKETONE IMMUNOPROTEASOME INHIBITOR, AND PRECURSORS THEREOF
    Publication number: 20200407334
    Abstract: Disclosed herein are methods for preparing [(2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound “G”): and precursors thereof.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Inventors: Henry Johnson, Sean Dalziel, Dustin McMinn
  • Crystalline salts of peptide epoxyketone immunoproteasome inhibitor
    Patent number: 10836756
    Abstract: Provided herein is a peptide epoxyketone immunoproteasome inhibitor having a structure: Formula (I) wherein X— is a counterion, crystal forms, salts, and processes for making the same, and formulations thereof.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: November 17, 2020
    Assignee: KEZAR LIFE SCIENCES
    Inventors: Henry Johnson, Evan Lewis, Sean Dalziel, Dustin McMinn