Abstract: A system for moving a cutting device gantry or similar structure on a material processing machine can include a mounting structure configured to be operably coupled to the gantry and a drive assembly movably coupled to the mounting structure. The drive assembly can be configured to move the mounting structure and the gantry in a first direction relative to a gantry guide shaft of the material processing machine. The drive assembly can also be movable relative to the mounting structure in a second direction, perpendicular to the first direction. In some embodiments, the system includes one or more guide wheels rotatably coupled to the mounting structure. Each of the guide wheels can include an annular outer portion having curvature configured to complimentarily engage the gantry guide shaft. The annular outer portion can be resiliently deformable and configured to conform to the gantry guide shaft during movement of thereon.