Patents by Inventor Duzheng WANG

Duzheng WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing dabigatran etexilate intermediate, and intermediate compound
    Patent number: 10112901
    Abstract: Disclosed are a method for preparing a dabigatran etexilate intermediate, and an intermediate compound. The method for preparing a dabigatran etexilate intermediate 4 comprises: reacting a compound 3 with a C1-C3 alkyl alcohol solution of methylamine in an organic solvent, wherein, X=chlorine, bromine, or iodine. Also disclosed are an intermediate compound 3 and a preparation method thereof. The method for preparing a dabigatran etexilate intermediate of the present invention has the advantages of simple process, easy operation, high yield, and easy purification, thus being suitable for industrial production.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: October 30, 2018
    Assignees: SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, CHINA STATE INSTITUTE OF PHARMACEUTICAL INDUSTRY, CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yajun Guo, Hanbin Shan, Xueyan Zhu, Zhedong Yuan, Xiong Yu, Meng Guo, Mingtong Hu, Duzheng Wang, Yu Huang
  • METHOD FOR PREPARING DABIGATRAN ETEXILATE INTERMEDIATE, AND INTERMEDIATE COMPOUND
    Publication number: 20170190666
    Abstract: Disclosed are a method for preparing a dabigatran etexilate intermediate, and an intermediate compound. The method for preparing a dabigatran etexilate intermediate 4 comprises; reacting a compound 3 with a C1-C3 alkyl alcohol solution of methylamine in an organic solvent, wherein, X=chlorine, bromine, or iodine. Also disclosed are an intermediate compound 3 and a preparation method thereof. The method for preparing a dabigatran etexilate intermediate of the present invention has the advantages of simple process, easy operation, high yield, and easy purification, thus being suitable for industrial production.
    Type: Application
    Filed: July 3, 2014
    Publication date: July 6, 2017
    Inventors: Yajun GUO, Hanbin SHAN, Xueyan ZHU, Zhedong YUAN, Xiong YU, Meng GUO, Mingtong HU, Duzheng WANG